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Psychiatric comorbidity and functioning in a clinically referred population of adults with autism spectrum disorders: a comparative study.

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TLDR
Adults with ASD have high levels of psychiatric comorbidity and dysfunction comparable to a clinically referred population of adults without ASD, and were functionally more impaired with a significant proportion having received both counseling and pharmacotherapy.
Abstract
To systematically examine the patterns of psychiatric comorbidity and functioning in clinically referred adults with autism spectrum disorders (ASD). Psychiatrically referred adults with and without ASD were compared on measures assessing for psychiatric comorbidity and psychosocial functioning. Sixty-three adults with ASD participated in the study (mean age: 29 ± 11 years). Adults with ASD in their lifetime suffered from a higher burden of psychiatric disorders (6 ± 3.4 vs. 3.5 ± 2.7; p < 0.001) including major depressive disorder and multiple anxiety disorders, and were functionally more impaired with a significant proportion having received both counseling and pharmacotherapy. Adults with ASD have high levels of psychiatric comorbidity and dysfunction comparable to a clinically referred population of adults without ASD.

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Citations
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Journal ArticleDOI

The health status of adults on the autism spectrum

TL;DR: Nearly all medical conditions were significantly more common in adults with autism, including immune conditions, gastrointestinal and sleep disorders, seizure, obesity, dyslipidemia, hypertension, and diabetes.
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Prevalence of co-occurring mental health diagnoses in the autism population: a systematic review and meta-analysis.

TL;DR: This systematic review and meta-analysis searched for publications between Jan 1, 1993, and Feb 1, 2019 in English or French that reported original research using an observational design on the prevalence of co-occurring mental health conditions in people with autism and reported confirmed clinical diagnoses of the co- Occurring conditions and autism using DSM or ICD criteria.
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College Students: Mental Health Problems and Treatment Considerations

TL;DR: By becoming familiar with the unique problems characteristic of the developmental stage and environment college students are in, practitioners will be able to better serve them.
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Identifying the lost generation of adults with autism spectrum conditions

TL;DR: In delineating differential diagnoses, true comorbidities, and overlapping behaviour with other psychiatric diagnoses, particular attention should be paid to anxiety, depression, obsessive-compulsive disorder, psychosis, personality disorders, and other neurodevelopmental disorders.
References
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Journal ArticleDOI

The Global Assessment Scale: A procedure for measuring overall severity of psychiatric disturbance.

TL;DR: The relative simplicity, reliability, and validity of the GAS suggests that it would be useful in a wide variety of clinical and research settings.
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Psychiatric disorders in children with autism spectrum disorders: Prevalence, comorbidity, and associated factors in a population-derived sample

TL;DR: Psychiatric disorders are common and frequently multiple in children with autism spectrum disorders and should be routinely evaluated in the clinical assessment of this group.
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Comorbid Psychiatric Disorders in Children with Autism: Interview Development and Rates of Disorders

TL;DR: The Kiddie Schedule for Affective Disorders and Schizophrenia was modified for use in children and adolescents with autism by developing additional screening questions and coding options that reflect the presentation of psychiatric disorders in autism spectrum disorders.
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Best estimate of lifetime psychiatric diagnosis: a methodological study.

TL;DR: It is shown that it is possible to make lifetime best estimate diagnoses reliably among both interviewed and noninterviewed individuals for most diagnostic categories and that diagnoses based on interview data alone are an adequate substitute for best estimate prescriptions based on all available information in a limited number of diagnostic categories.
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