Journal ArticleDOI
Recent developments in PDMS surface modification for microfluidic devices
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TLDR
This review will present recent research on surface modifications of PDMS using techniques ranging from metal layer coatings and layer‐by‐layer depositions to dynamic surfactant treatments and the adsorption of amphipathic proteins.Abstract:
PDMS is enjoying continued and ever increasing popularity as the material of choice for microfluidic devices due to its low cost, ease of fabrication, oxygen permeability and optical transparency. However, PDMS's hydrophobicity and fast hydrophobic recovery after surface hydrophilization, attributed to its low glass transition temperature of less than -120 degrees C, negatively impacts on the performance of PDMS-based microfluidic device components. This issue has spawned a flurry of research to devise longer lasting surface modifications of PDMS, with particular emphasis on microfluidic applications. This review will present recent research on surface modifications of PDMS using techniques ranging from metal layer coatings and layer-by-layer depositions to dynamic surfactant treatments and the adsorption of amphipathic proteins. We will also discuss significant advances that have been made with a broad palette of gas-phase processing methods including plasma processing, sol-gel coatings and chemical vapor deposition. Finally, we will present examples of applications and future prospects of modified PDMS surfaces in microfluidics, in areas such as molecular separations, cell culture in microchannels and biomolecular detection via immunoassays.read more
Citations
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Journal ArticleDOI
Continuous directional water transport on the peristome surface of Nepenthes alata
Huawei Chen,Pengfei Zhang,Liwen Zhang,Hongliang Liu,Y. Jiang,Deyuan Zhang,Zhiwu Han,Lei Jiang,Lei Jiang +8 more
TL;DR: It is found that continuous, directional water transport occurs on the surface of the ‘peristome’—the rim of the pitcher—because of its multiscale structure, which optimizes and enhances capillary rise in the transport direction, and prevents backflow by pinning in place any water front that is moving in the reverse direction.
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Materials for Microfluidic Chip Fabrication
TL;DR: The evolution of chip materials reflects the two major trends of microfluidic technology: powerful microscale research platforms and low-cost portable analyses.
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Skin-inspired hydrogel-elastomer hybrids with robust interfaces and functional microstructures
TL;DR: Zhao et al. as discussed by the authors proposed a simple yet versatile method to assemble hydrogels and elastomers into hybrids with extremely robust interfaces (interfacial toughness over 1,000 Jm−2) and functional microstructures such as microfluidic channels and electrical circuits.
Journal ArticleDOI
Droplet Microfluidics—A Tool for Single-Cell Analysis
TL;DR: An overview of the current state of single-cell analysis involving droplet microfluidics is given and examples where dropletmicrofluidic can further biological understanding are offered.
Journal ArticleDOI
Oxygen plasma treatment for reducing hydrophobicity of a sealed polydimethylsiloxane microchannel
TL;DR: A simple and easy protocol combining a second extended oxygen plasma treatments and proper storage to produce usable hydrophilic PDMS devices is reported.
References
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Journal ArticleDOI
Surface modification of Sylgard-184 poly(dimethyl siloxane) networks by ultraviolet and ultraviolet/ozone treatment.
TL;DR: The results reveal that when exposed to UV, the PDMS macromolecules in the surface region of Sylgard-184 undergo chain scission, involving both the main chain backbone and the side groups, and form a network whose wetting properties are similar to those of a UV-modified model PDMS.
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Surface modification of poly(dimethylsiloxane) microchannels
TL;DR: This review looks at the efforts that are being made to modify the surface of poly(dimethylsiloxane) (PDMS) microchannels, in order to enhance applicability in the field of microfluidics.
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Hydrophilization and hydrophobic recovery of PDMS by oxygen plasma and chemical treatment—An SEM investigation
TL;DR: In this paper, the mechanism of hydrophilic recovery of polydimethylsiloxane (PDMS) was investigated taking into consideration physical and chemical parameters using SEM characterization. But, the authors did not consider the role of the morphology of the film surface nanostructuring of PDMS.
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Crosslinked polydimethylsiloxane exposed to oxygen plasma studied by neutron reflectometry and other surface specific techniques
TL;DR: In this paper, spin-coated specimens of crosslinked polydimethylsiloxane (PDMS) exposed to radio-frequency (RF) and microwave (MW) oxygen plasma were studied by specular neutron reflectometry, X-ray photoelectron spectroscopy (XPS), Wilhelmy balance, contact angle measurements, scanning electron microscopy and atomic force microscopy.
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Surface modification of poly(dimethylsiloxane) microfluidic devices by ultraviolet polymer grafting.
TL;DR: A one-step procedure to covalently link polymers to the surface of PDMS microchannels by ultraviolet graft polymerization is demonstrated and it is shown that by using the appropriate monomer, it should be possible to use UV grafting to impart a variety of surface properties toPDMS microfluidics devices.