Open Access
Regional Brain Metabolic Changes in Patients With Major Depression Treated With Either Paroxetine or Interpersonal Therapy
Arthur L. Brody,Sanjaya Saxena,Paula Stoessel,Laurie A. Gillies,Lynn A. Fairbanks,Shervin Alborzian,Michael E. Phelps,Sung-Cheng Huang,Hsiao-Ming Wu,Matthew L. Ho,Mai K. Ho,Scott C. Au,Karron M. Maidment +12 more
TLDR
Subjects with MDD had regional brain metabolic abnormalities at baseline that tended to normalize with treatment, and regional metabolic changes appeared similar with the 2 forms of treatment.About:
The article was published on 2017-01-01 and is currently open access. It has received 507 citations till now. The article focuses on the topics: Depression (differential diagnoses).read more
Citations
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Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression
TL;DR: Because the MPFC and related limbic structures provide forebrain modulation over visceral control structures in the hypothalamus and brainstem, their dysfunction can account for the disturbances in autonomic regulation and neuroendocrine responses that are associated with mood disorders.
Journal ArticleDOI
Neurobiology of emotion perception II: Implications for major psychiatric disorders
TL;DR: It is suggested that distinct patterns of structural and functional abnormalities in neural systems important for emotion processing are associated with specific symptoms of schizophrenia and bipolar and major depressive disorder.
Journal ArticleDOI
Prefrontal-subcortical pathways mediating successful emotion regulation.
TL;DR: Evidence is provided that right ventrolateral prefrontal region (vlPFC) is involved in both the generation and regulation of emotion through different subcortical pathways, suggesting a general role for this region in appraisal processes.
Journal ArticleDOI
Efficacy and safety of transcranial magnetic stimulation in the acute treatment of major depression: A multisite randomized controlled trial.
John P. O'Reardon,H. Brent Solvason,Philip G. Janicak,Shirlene Sampson,Keith E. Isenberg,Ziad Nahas,William M. McDonald,David H. Avery,Paul B. Fitzgerald,Colleen Loo,Mark A. Demitrack,Mark S. George,Harold A. Sackeim +12 more
TL;DR: Transcranial magnetic stimulation was effective in treating major depression with minimal side effects reported and offers clinicians a novel alternative for the treatment of this disorder.
Journal ArticleDOI
Neurocircuitry of Mood Disorders
Joseph L. Price,Wayne C. Drevets +1 more
TL;DR: A system has been described that links the medial prefrontal cortex and a few related cortical areas to the amygdala, the ventral striatum and pallidum, the medial thalamus, the hypothalamus, and the periaqueductal gray and other parts of the brainstem, which indicates that this system is centrally involved in mood disorders.
References
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Statistical parametric maps in functional imaging: A general linear approach
Karl J. Friston,Andrew P. Holmes,Keith J. Worsley,J-B. Poline,Chris D. Frith,Richard S. J. Frackowiak +5 more
TL;DR: In this paper, the authors present a general approach that accommodates most forms of experimental layout and ensuing analysis (designed experiments with fixed effects for factors, covariates and interaction of factors).
Book
Co-planar stereotaxic atlas of the human brain : 3-dimensional proportional system : an approach to cerebral imaging
TL;DR: Direct and Indirect Radiologic Localization Reference System: Basal Brain Line CA-CP Cerebral Structures in Three-Dimensional Space Practical Examples for the Use of the Atlas in Neuroradiologic Examinations Three- Dimensional Atlas of a Human Brain Nomenclature-Abbreviations Anatomic Index Conclusions.
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Parallel Organization of Functionally Segregated Circuits Linking Basal Ganglia and Cortex
TL;DR: The basal ganglia serve primarily to integrate diverse inputs from the entire cerebral cortex and to "funnel" these influences, via the ventrolateral thalamus, to the motor cortex.