SARS-CoV-2 B.1.1.7 lineage rapidly spreads and replaces R.1 lineage in Japan: Serial and stationary observation in a community.
Yosuke Hirotsu,Masao Omata +1 more
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TLDR
In this article, the transition of viral lineage in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was investigated by stationary genome analysis in Yamanashi, Japan.About:
This article is published in Infection, Genetics and Evolution.The article was published on 2021-09-21 and is currently open access. It has received 16 citations till now. The article focuses on the topics: Lineage (genetic).read more
Citations
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Journal ArticleDOI
SARS-CoV-2 Omicron sublineage BA.2 replaces BA.1.1: Genomic surveillance in Japan from September 2021 to March 2022
Yosuke Hirotsu,Makoto Maejima,Masahiro Shibusawa,Yume Natori,Yuki Nagakubo,Kazuhiro Hosaka,Hitomi Sueki,Hitoshi Mochizuki,Toshiharu Tsutsui,Yumiko Kakizaki,Yoshihiro Miyashita,Masao Omata +11 more
TL;DR: In this article , the authors reported the impact of vaccination and pre-immunity on the proliferation of Omicron BA.1 and BA.2 across all age groups.
Journal ArticleDOI
Direct comparison of Xpert Xpress, FilmArray Respiratory Panel, Lumipulse antigen test, and RT-qPCR in 165 nasopharyngeal swabs
Yosuke Hirotsu,Makoto Maejima,Masahiro Shibusawa,Yume Natori,Yuki Nagakubo,Kazuhiro Hosaka,Hitomi Sueki,Kenji Amemiya,Miyoko Hayakawa,Hitoshi Mochizuki,Toshiharu Tsutsui,Yumiko Kakizaki,Yoshihiro Miyashita,Masao Omata +13 more
TL;DR: In this article , the authors investigated the assay performance of two nucleic acid amplification tests (Xpert Xpress SARS-CoV-2 and FilmArray Respiratory Panel) and a quantitative antigen test (Lumipulse).
Journal ArticleDOI
Classification of Omicron BA.1, BA.1.1, and BA.2 sublineages by TaqMan assay consistent with whole genome analysis data
Yosuke Hirotsu,Makoto Maejima,Masahiro Shibusawa,Yume Natori,Yuki Nagakubo,Kazuhiro Hosaka,Hitomi Sueki,Hitoshi Mochizuki,Toshiharu Tsutsui,Yumiko Kakizaki,Yoshihiro Miyashita,Masao Omata +11 more
TL;DR: In this paper , a TaqMan assay was constructed for rapid identification and genotyping of Omicron sublineages with 171 SARS-CoV-2 positive samples.
Journal ArticleDOI
Cross-Neutralizing Breadth and Longevity Against SARS-CoV-2 Variants After Infections
Yuki Kurahashi,Silvia Sutandhio,Koichi Furukawa,Lidya Handayani Tjan,Sachiyo Iwata,Shigeru Sano,Yoshiki Tohma,Hiroyuki Ohkita,Sachiko Nakamura,Mitsuhiro Nishimura,Jun Arii,Tatsunori Kiriu,E. Yamamoto,Tatsuya Nagano,Yoshihiro Nishimura,Yasuko Mori +15 more
TL;DR: The results indicate that neutralizing antibodies that recognize the common epitope for several variants may be maintained for a long time, whileneutralizing antibodies having specific epitopes for a variant, produced in large quantities immediately after infection, may decrease quite rapidly.
Posted ContentDOI
Similar viral loads in Omicron infections regardless of vaccination status
Yosuke Hirotsu,Madoka Maejima,Masahiro Shibusawa,Yoichiro Natori,Yuki Nagakubo,Kazuhiro Hosaka,Hitomi Sueki,Hitoshi Mochizuki,Toshiharu Tsutsui,Yumiko Kakizaki,Yuri Miyashita,Masao Omata +11 more
TL;DR: Omicron-infected patients who had received a third vaccine dose had viral loads similar to patients with two doses or who were unvaccinated, and no correlations between age and BA.1.1 andBA.2 viral load were observed.
References
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Journal ArticleDOI
Risk of mortality in patients infected with SARS-CoV-2 variant of concern 202012/1: matched cohort study.
Robert Challen,Ellen Brooks-Pollock,Jonathan M. Read,Louise Dyson,Krasimira Tsaneva-Atanasova,Krasimira Tsaneva-Atanasova,Leon Danon +6 more
TL;DR: In this article, a matched cohort study was conducted to establish whether there is any change in mortality from infection with a new variant of SARS-CoV-2, designated a variant of concern (VOC-202012/1) in December 2020, compared with circulating SARS CoV-19 variants.
Journal ArticleDOI
Identification of SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization.
Zhuoming Liu,Laura A. VanBlargan,Louis Marie Bloyet,Paul W. Rothlauf,Paul W. Rothlauf,Rita E. Chen,Spencer Stumpf,Haiyan Zhao,John M. Errico,Elitza S. Theel,Mariel J. Liebeskind,Brynn Alford,William Buchser,Ali H. Ellebedy,Daved H. Fremont,Michael S. Diamond,Sean P. J. Whelan +16 more
TL;DR: In this article, a VSV-eGFP-SARS-CoV-2-S chimeric virus was exposed to 19 neutralizing monoclonal antibodies (mAbs) against the receptor-binding domain (RBD) and generated 50 different escape mutants.
Journal ArticleDOI
BNT162b2-elicited neutralization of B.1.617 and other SARS-CoV-2 variants.
Jianying Liu,Yang Liu,Hongjie Xia,Jing Zou,Scott C. Weaver,Kena A. Swanson,Hui Cai,Mark Cutler,David A. Cooper,Alexander Muik,Kathrin U. Jansen,Ugur Sahin,Xuping Xie,Philip R. Dormitzer,Pei Yong Shi +14 more
TL;DR: The authors showed that serum samples taken from twenty human volunteers, two or four weeks after their second dose of the BNT162b2 vaccine, neutralize engineered SARS-CoV-2 with a USA-WA1/2020 genetic background (a virus strain isolated in January 2020) and spike glycoproteins from the recently identified B.1.617.
Journal ArticleDOI
Evidence for increased breakthrough rates of SARS-CoV-2 variants of concern in BNT162b2-mRNA-vaccinated individuals.
Talia Kustin,Noam Harel,Uriah Finkel,Shay Perchik,Sheri Harari,Maayan Tahor,Itamar Caspi,Rachel Levy,Michael Leshchinsky,Shifra Ken Dror,Galit Bergerzon,Hala Gadban,Faten Gadban,Eti Eliassian,Orit Shimron,Loulou Saleh,Haim Ben-Zvi,Elena Keren Taraday,Doron Amichay,Doron Amichay,Anat Ben-Dor,Dana Sagas,Merav Strauss,Yonat Shemer Avni,Amit Huppert,Amit Huppert,Eldad Kepten,Ran D. Balicer,Doron Netzer,Shay Ben-Shachar,Shay Ben-Shachar,Adi Stern +31 more
TL;DR: In this paper, a matched cohort study was conducted to examine the distribution of VOCs in infections of BNT162b2 mRNA vaccinees from Clalit Health Services (Israel) using viral genomic sequencing, and hypothesized that if vaccine effectiveness against a VOC is reduced, its proportion among breakthrough cases would be higher than in unvaccinated controls.
Journal ArticleDOI
Novel SARS-CoV-2 variants: the pandemics within the pandemic.
TL;DR: A review of the current knowledge of emerging SARS-CoV-2 variants, particularly those deemed VOC/Is: B.1.351, B.7, and P.1, can be found in the MEDLINE and BioRxiv databases as discussed by the authors.
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