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Edmond Chan

Researcher at University of British Columbia

Publications -  100
Citations -  16668

Edmond Chan is an academic researcher from University of British Columbia. The author has contributed to research in topics: Medicine & Autophagy. The author has an hindex of 33, co-authored 53 publications receiving 13973 citations. Previous affiliations of Edmond Chan include University of Alberta & University of Strathclyde.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes

TL;DR: The mammalian homologue of Atg9p, a multi-spanning transmembrane protein essential in yeast for autophagy, is studied to gain a better understanding of the function of this ubiquitious protein.
Journal ArticleDOI

RasGRP, a Ras Guanyl Nucleotide- Releasing Protein with Calcium- and Diacylglycerol-Binding Motifs

TL;DR: Sustained ligand-induced signaling and membrane partitioning were absent when the DAG-binding domain was deleted and RasGRP is expressed in the nervous system, where it may couple changes in DAG and possibly calcium concentrations to Ras activation.