Journal ArticleDOI
The cellular effects of PM2.5 collected in Chinese Taiyuan and Guangzhou and their associations with polycyclic aromatic hydrocarbons (PAHs), nitro-PAHs and hydroxy-PAHs
TLDR
In this paper, the effects of region and season-dependent differences of PM2.5 on cytotoxicity, and the contributions of PAHs, nitro-PAHs (N-PAHLs) and hydroxy-PAHSs (OH-PAHRs) to PM2., were examined by determining different toxicological indicators in three lung cell lines.About:
This article is published in Ecotoxicology and Environmental Safety.The article was published on 2020-03-15. It has received 31 citations till now.read more
Citations
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Reactive oxygen species production and inflammatory effects of ambient PM2.5 -associated metals on human lung epithelial A549 cells "one year-long study": The Delhi chapter.
TL;DR: In Delhi most toxic seasons for respiratory system are winter and post-monsoon and safest season is monsoon, and the presence of Fe in winter and pre- monsoon seasons catalysed the ROS production.
Journal ArticleDOI
Occurrence and distribution of typical semi-volatile organic chemicals (SVOCs) in paired indoor and outdoor atmospheric fine particle samples from cities in southern China.
TL;DR: Paired indoor and outdoor atmospheric fine particle samples collected from 15 homes representing five typical urban cities in southern China indicated that inhalation exposure to typical SVOCs posed no non-carcinogenic risks to the human body.
Journal ArticleDOI
Sperm mtDNA copy number, telomere length, and seminal spermatogenic cells in relation to ambient air pollution: Results of a cross-sectional study in Jing-Jin-Ji region of China.
Lixiao Zhou,Lipeng Li,Guimin Hao,Binghua Li,Sujuan Yang,Ning Wang,Jiaming Liang,Hongyue Sun,Shitao Ma,Lina Yan,Chunfang Zhao,Yanjing Wei,Yujie Niu,Rong Zhang +13 more
TL;DR: The findings indicate CO and PM might impair semen quality testicularly and post-testicularly while seminal spermatogenic cell, STL and mtDNAcn change indicate necessity for more attention on these mechanisms.
Journal ArticleDOI
Discovery of emerging sulfur-containing PAHs in PM2.5: Contamination profiles and potential health risks
Yanhao Zhang,Yuanyuan Song,Yi-Jie Chen,Yanyan Chen,Yan Lu,Ruijin Li,Chuan Dong,Di Hu,Zongwei Cai,Zongwei Cai +9 more
TL;DR: The results illustrated that PASHs in PM2.5 possibly caused oxidative stress and inhibition of human bronchial epithelial cells in seriously polluted regions such as Taiyuan, suggesting that the pollutant-induced health concerns may need more investigations.
Journal ArticleDOI
The effect of toxic components on metabolomic response of male SD rats exposed to fine particulate matter.
Ningbo Geng,Xiaoyao Song,Rong Cao,Yun Luo,Mila A,Cai Zhengang,Yu Kejie,Yuan Gao,Yuwen Ni,Haijun Zhang,Jiping Chen +10 more
TL;DR: High levels of organic compounds such as PAHs, PCBs and PCDD/Fs in winter PM2.5 bring multiple overlaps on the toxic pathways, resulting in larger pulmonary toxicity and metabolic toxicity in rats than summer, even at environmentally relevant doses.
References
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Lung Cancer, Cardiopulmonary Mortality, and Long-term Exposure to Fine Particulate Air Pollution
C. Arden Pope,Richard T. Burnett,Michael J. Thun,Eugenia E. Calle,Daniel Krewski,Kazuhiko Ito,George D. Thurston +6 more
TL;DR: Fine particulate and sulfur oxide--related pollution were associated with all-cause, lung cancer, and cardiopulmonary mortality and long-term exposure to combustion-related fine particulate air pollution is an important environmental risk factor for cardiopULmonary and lung cancer mortality.
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Air pollution and health.
TL;DR: The evidence for adverse effects on health of selected air pollutants is discussed, and it is unclear whether a threshold concentration exists for particulate matter and ozone below which no effect on health is likely.
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Cancer risk assessment, indicators, and guidelines for polycyclic aromatic hydrocarbons in the ambient air.
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TL;DR: The carcinogenicity of polycyclic aromatic hydrocarbons (PAHs) is associated with the complexity of the molecule, and with metabolic activation to reactive diol epoxide intermediates and their subsequent covalent binding to critical targets in DNA.
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Air pollution and lung cancer incidence in 17 European cohorts : Prospective analyses from the European Study of Cohorts for Air Pollution Effects (ESCAPE)
Ole Raaschou-Nielsen,Zorana Jovanovic Andersen,Rob Beelen,Evangelia Samoli,Massimo Stafoggia,Gudrun Weinmayr,Barbara Hoffmann,Paul Fischer,Mark J. Nieuwenhuijsen,Bert Brunekreef,Wei W. Xun,Klea Katsouyanni,Konstantina Dimakopoulou,Johan Nilsson Sommar,Bertil Forsberg,Lars Modig,Anna Oudin,Bente Oftedal,Per E. Schwarze,Per Nafstad,Per Nafstad,Ulf de Faire,Nancy L. Pedersen,Claes-Göran Östenson,Laura Fratiglioni,Johanna Penell,Michal Korek,Göran Pershagen,Kirsten Thorup Eriksen,Mette Sørensen,Anne Tjønneland,Thomas Ellermann,Marloes Eeftens,Petra H.M. Peeters,Kees Meliefste,Meng Wang,Bas Bueno-de-Mesquita,Timothy J. Key,Kees de Hoogh,Hans Concin,Gabriele Nagel,Alice Vilier,Alice Vilier,Sara Grioni,Vittorio Krogh,Ming-Yi Tsai,Ming-Yi Tsai,Fulvio Ricceri,Carlotta Sacerdote,C Galassi,Enrica Migliore,Andrea Ranzi,Giulia Cesaroni,Chiara Badaloni,Francesco Forastiere,Ibon Tamayo,Pilar Amiano,Miren Dorronsoro,Antonia Trichopoulou,Christina Bamia,Paolo Vineis,Gerard Hoek +61 more
TL;DR: The meta-analyses showed a statistically significant association between risk for lung cancer and PM10 and PM2·5, and no association between lungcancer and nitrogen oxides concentration or traffic intensity on the nearest street.
Journal ArticleDOI
Fine particulate matter (PM 2.5) in China at a city level
Yan-Lin Zhang,Fang Cao +1 more
TL;DR: It is found only 25 out of 190 cities could meet the National Ambient Air Quality Standards of China, and the population-weighted mean of PM2.5 in Chinese cities are 61 μg/m3, ~3 times as high as global population- Weighted mean, highlighting a high health risk.