The epidemiology and impact of pain in osteoarthritis.
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TLDR
More insights are needed into pain mechanisms in OA to enable rational mechanism-based management of pain and to contribute to a substantial socioeconomic burden.About:
This article is published in Osteoarthritis and Cartilage.The article was published on 2013-09-01 and is currently open access. It has received 1096 citations till now. The article focuses on the topics: Chronic pain & Osteoarthritis.read more
Citations
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Animal models of osteoarthritis: classification, update, and measurement of outcomes.
TL;DR: This review summarizes the current understanding of the disease pathogenesis, invasive and non-invasive animal models, imaging modalities, and pain assessment techniques in the animals.
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Osteoarthritis: Pathology, Diagnosis, and Treatment Options.
TL;DR: The pathology, symptoms, diagnosis, and various conservative, surgical, and novel treatments of OA are reviewed.
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Knee extensor muscle weakness is a risk factor for development of knee osteoarthritis. A systematic review and meta-analysis
TL;DR: This systematic review and meta-analysis showed that knee extensor muscle weakness was associated with an increased risk of developing knee osteoarthritis in both men and women.
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Intraarticular injections (corticosteroid, hyaluronic acid, platelet rich plasma) for the knee osteoarthritis
TL;DR: There is no data that any of the IA injections will cause osteophytes to regress or cartilage and meniscus to regenerate in patients with substantial and irreversible bone and cartilage damage, so IA corticosteroid injections are safe and have positive effects for patient satisfaction.
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Curcuminoid treatment for knee osteoarthritis: a randomized double-blind placebo-controlled trial.
Yunes Panahi,Alireza Rahimnia,Mojtaba Sharafi,Gholam Hossein Alishiri,Amin Saburi,Amirhossein Sahebkar +5 more
TL;DR: In patients with mild‐to‐moderate knee OA, curcuminoids represent an effective and safe alternative treatment for OA and there was no considerable adverse effect in both groups.
References
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Journal Article
Social environment moderates the association between catastrophizing and pain among persons with a spinal cord injury. Authors' reply
Kenneth Mchenry,Nicholas D. Giardino,Mark P. Jensen,Judith A. Turner,Dawn M. Ehde,Diana D. Cardenas +5 more
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Symptomatic hand osteoarthritis in the United States: prevalence and functional impairment estimates from the third U.S. National Health and Nutrition Examination Survey, 1991-1994
TL;DR: The NHANES III data provide a population-based assessment of the impact and associated functional impairments of symptomatic hand osteoarthritis, which affects 1 in 12 older United States adults.
Journal ArticleDOI
Weight loss as treatment for knee osteoarthritis symptoms in obese patients: 1-year results from a randomised controlled trial
TL;DR: Continuous reinforcement of a weight loss programme can be successful over a year in obese knee OA patients, and the overall clinical benefits of the intervention on health should lead to a strong recommendation of weight loss in this group of patients.
Journal ArticleDOI
The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis
Ana M. Valdes,Gert De Wilde,Sally Doherty,Rik Lories,Frances L. Vaughn,Laura L Laslett,Rose A. Maciewicz,Anushka Soni,Deborah J. Hart,Weiya Zhang,Kenneth Muir,Elaine M. Dennison,Margaret Wheeler,Paul E. Leaverton,Cyrus Cooper,Cyrus Cooper,Tim D. Spector,Flavia M. Cicuttini,Victoria Chapman,Graeme Jones,Nigel K Arden,Nigel K Arden,Michael Doherty +22 more
TL;DR: A genotype involved in lower peripheral pain sensitivity is significantly associated with a decreased risk of painful knee OA, which indicates a role for the pro-nociceptive gene TRPV1 in genetic susceptibility to symptomatic knee Oa, which may also be influenced by a role by this molecule in cartilage function.
Journal ArticleDOI
Relationship between social desirability and self-report in chronic pain patients.
TL;DR: Correlations showed that patients with greater social desirability response bias reported less depression and anxiety but higher levels of pain severity, suggesting that social desIRability response biases should be considered in both research and clinical assessments of chronic pain patients.
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