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Open AccessJournal ArticleDOI

The epidemiology and impact of pain in osteoarthritis.

Tuhina Neogi
- 01 Sep 2013 - 
- Vol. 21, Iss: 9, pp 1145-1153
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TLDR
More insights are needed into pain mechanisms in OA to enable rational mechanism-based management of pain and to contribute to a substantial socioeconomic burden.
About: 
This article is published in Osteoarthritis and Cartilage.The article was published on 2013-09-01 and is currently open access. It has received 1096 citations till now. The article focuses on the topics: Chronic pain & Osteoarthritis.

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Citations
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Journal ArticleDOI

A mechanism-based pain sensitivity index to characterize knee osteoarthritis patients with different disease stages and pain levels.

Lars Arendt-Nielsen, +6 more
- 01 Nov 2015 - 
TL;DR: In a cohort of well‐characterized patients with different degrees of knee osteoarthritis and pain, mechanism‐based quantitative sensory testing (QST) is utilized to characterize subgroups of patients and analyse the associations between clinical characteristics and QST.
Journal ArticleDOI

Total knee arthroplasty: improving outcomes with a multidisciplinary approach.

James E. Feng, +3 more
- 25 Jan 2018 - 
TL;DR: A review of several systems based programs and specialty care practices that can be adopted into the standard orthopedic practice to enhance TKA outcomes while minimizing unnecessary expenditures is reviewed.
Journal ArticleDOI

Midterm Clinical Outcomes and MR Imaging Changes after Transcatheter Arterial Embolization as a Treatment for Mild to Moderate Radiographic Knee Osteoarthritis Resistant to Conservative Treatment.

Yuji Okuno, +4 more
- 01 Jul 2017 - 
TL;DR: Transcatheter arterial embolization significantly improved pain symptoms and clinical function in patients with mild to moderate knee OA that was resistant to conservative treatment.
Journal ArticleDOI

Enhanced Pain Sensitivity Among Individuals With Symptomatic Knee Osteoarthritis: Potential Sex Differences in Central Sensitization

Emily J. Bartley, +14 more
- 01 Apr 2016 - 
TL;DR: Differences in peripheral and central sensitization in men and women with symptomatic knee OA are examined, as well as to determine whether these differences vary across age (middle age versus older age).
Journal ArticleDOI

Cytokines and Chemokines Involved in Osteoarthritis Pathogenesis

Vilim Molnar, +18 more
- 26 Aug 2021 - 
TL;DR: In this paper, the authors analyzed individual cytokines involved in the immune processes with an emphasis on their function in osteoarthritis and found that the concentration of both proinflammatory and anti-inflammatory cytokines were altered depending on the OA stage and activity.
References
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Journal Article

Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee.

Nicholas Bellamy, +4 more
- 01 Dec 1988 - 
TL;DR: WOMAC is a disease-specific purpose built high performance instrument for evaluative research in osteoarthritis clinical trials and fulfil conventional criteria for face, content and construct validity, reliability, responsiveness and relative efficiency.
Journal ArticleDOI

Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030.

Steven M. Kurtz, +4 more
- 01 Apr 2007 - 
TL;DR: These large projected increases in demand for total hip and knee arthroplasties provide a quantitative basis for future policy decisions related to the numbers of orthopaedic surgeons needed to perform these procedures and the deployment of appropriate resources to serve this need.
Journal ArticleDOI

Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010

Theo Vos, +363 more
- 15 Dec 2012 - 
TL;DR: Prevalence and severity of health loss were weakly correlated and age-specific prevalence of YLDs increased with age in all regions and has decreased slightly from 1990 to 2010, but population growth and ageing have increased YLD numbers and crude rates over the past two decades.
Journal Article

Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010 (vol 380, pg 2197, 2012)

Christopher J L Murray, +4 more
- 01 Jan 2013 - 
TL;DR: In this article, a comprehensive update of disease burden worldwide incorporating a systematic reassessment of disease and injury-specific epidemiology has been done since the 1990 study, and the authors aimed to calculate disease burden globally and for 21 regions for 1990, 2005, and 2010 with methods to enable meaningful comparisons over time.
Journal ArticleDOI

Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010

Christopher J L Murray, +369 more
- 15 Dec 2012 - 
TL;DR: The results for 1990 and 2010 supersede all previously published Global Burden of Disease results and highlight the importance of understanding local burden of disease and setting goals and targets for the post-2015 agenda taking such patterns into account.
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