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The epidemiology of co-occurring addictive and mental disorders: implications for prevention and service utilization.

TLDR
General population data from the National Comorbidity Survey are presented on co-occurring DSM-III-R addictive and mental disorders, with the finding that fewer than half of cases with 12-monthCo-occurrence received any treatment in the year prior to interview suggests the need for greater outreach efforts.
Abstract
General population data from the National Comorbidity Survey are presented on co-occurring DSM-III-R addictive and mental disorders. Co-occurrence is highly prevalent in the general population and usually due to the association of a primary mental disorder with a secondary addictive disorder. It is associated with a significantly increased probability of treatment, although the finding that fewer than half of cases with 12-month co-occurrence received any treatment in the year prior to interview suggests the need for greater outreach efforts.

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Brain volume abnormalities in major depressive disorder: a meta-analysis of magnetic resonance imaging studies

TL;DR: This is the first comprehensive meta‐analysis in major depressive disorder demonstrating structural brain abnormalities, particularly in those brain areas that are involved in emotion processing and stress‐regulation.
Journal ArticleDOI

Neurobiological similarities in depression and drug dependence : A self-medication hypothesis

TL;DR: It is concluded that drug dependence and depression may be associated with alterations in some of the same neurotransmitter systems and, in particular, with alterations of neurotransmitter function in limbic-related brain structures, and may be linked by some shared neurobiology.
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Axis I psychiatric comorbidity and its relationship to historical illness variables in 288 patients with bipolar disorder

TL;DR: Comorbid lifetime and current axis I disorders in 288 patients with bipolar disorder and the relationships of these comorbid disorders to selected demographic and historical illness variables showed associations with earlier age at onset of affective symptoms and syndromal bipolar disorder.
Journal ArticleDOI

The National Comorbidity Survey Replication (NCS-R): background and aims.

TL;DR: The National Comorbidity Survey Replication was designed to investigate time trends and their correlates over the decade of the 1990s and expand the assessment of the prevalence and correlates of mental disorders beyond the assessment in the baseline NCS in order to address a number of important substantive and methodological issues that were raised by the NCS.
Journal ArticleDOI

Prevalence of comorbid substance use, anxiety and mood disorders in epidemiological surveys, 1990-2014: a systematic review and meta-analysis

TL;DR: The strong association between SUDs, mood and anxiety disorders is confirmed worldwide as a factor that affects the profile, course, patterns, severity and outcomes of these disorders.
References
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Journal ArticleDOI

Lifetime and 12-Month Prevalence of DSM-III-R Psychiatric Disorders in the United States: Results From the National Comorbidity Survey

TL;DR: The prevalence of psychiatric disorders is greater than previously thought to be the case, and morbidity is more highly concentrated than previously recognized in roughly one sixth of the population who have a history of three or more comorbid disorders.
Journal ArticleDOI

Posttraumatic stress disorder in the National Comorbidity Survey.

TL;DR: Progress in estimating age-at-onset distributions, cohort effects, and the conditional probabilities of PTSD from different types of trauma will require future epidemiologic studies to assess PTSD for all lifetime traumas rather than for only a small number of retrospectively reported "most serious" traumAs.
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National Institute of Mental Health diagnostic interview schedule: Its history, characteristics, and validity.

TL;DR: In this article, a new interview schedule allows lay interviewers or clinicians to make psychiatric diagnoses according to DSM-III criteria, Feighner criteria, and Research Diagnostic Criteria.
Journal ArticleDOI

Reliability and validity studies of the WHO-Composite International Diagnostic Interview (CIDI): A critical review

TL;DR: The CIDI is a comprehensive and fully standardized diagnostic interview designed for assessing mental disorders according to the definitions of the Diagnostic Criteria for Research of ICD-10 and DSM-III-R and was found to be appropriate for use in different kinds of settings and countries.
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