The human milk microbiome changes over lactation and is shaped by maternal weight and mode of delivery
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TLDR
The results indicate that milk bacteria are not contaminants and suggest that the milk microbiome is influenced by several factors that significantly skew its composition, which emphasize the necessity to understand the biological role that the Milk microbiome could potentially play for human health.About:
This article is published in The American Journal of Clinical Nutrition.The article was published on 2012-09-01 and is currently open access. It has received 687 citations till now. The article focuses on the topics: Breast milk & Colostrum.read more
Citations
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Human milk composition: nutrients and bioactive factors
TL;DR: The composition of human milk is the biological norm for infant nutrition and contains many hundreds to thousands of distinct bioactive molecules that protect against infection and inflammation and contribute to immune maturation, organ development, and healthy microbial colonization.
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The composition of the gut microbiota throughout life, with an emphasis on early life.
Juan M. Rodríguez,Kiera Murphy,Catherine Stanton,R. Paul Ross,Olivia I. Kober,Nathalie Juge,Ekaterina Avershina,Knut Rudi,Arjan Narbad,Maria C. Jenmalm,Julian Marchesi,Maria Carmen Collado +11 more
TL;DR: A review discusses recent studies on the early colonization and factors influencing this process which impact on health and an adequate establishment of microbiota and its maintenance throughout life would reduce the risk of disease in early and late life.
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Human gut colonisation may be initiated in utero by distinct microbial communities in the placenta and amniotic fluid
TL;DR: It is proposed that the stepwise microbial gut colonisation process may be initiated already prenatally by a distinct microbiota in the placenta and amniotic fluid, and the link between the mother and the offspring is continued after birth by microbes present in breast milk.
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The infant microbiome development: mom matters
Noel T. Mueller,Elizabeth Bakacs,Joan Combellick,Zoya Grigoryan,Maria Gloria Dominguez-Bello +4 more
TL;DR: Recent knowledge about the impacts on infant microbiome assembly is reviewed, preventive and restorative strategies to ameliorate the effects of these impacts are discussed, and where research is needed to advance this field and improve the health of future generations are highlighted.
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Mom knows best: the universality of maternal microbial transmission.
TL;DR: Evidence for microbial maternal transmission is increasingly widespread across animals, and collective knowledge compels a paradigm shift—one in which maternal transmission of microbes advances from a taxonomically specialized phenomenon to a universal one in animals.
References
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A core gut microbiome in obese and lean twins
Peter J. Turnbaugh,Micah Hamady,Tanya Yatsunenko,Brandi L. Cantarel,Alexis E. Duncan,Ruth E. Ley,Mitchell L. Sogin,William J. Jones,Bruce A. Roe,Jason P. Affourtit,Michael Egholm,Bernard Henrissat,Andrew C. Heath,Rob Knight,Jeffrey I. Gordon +14 more
TL;DR: The faecal microbial communities of adult female monozygotic and dizygotic twin pairs concordant for leanness or obesity, and their mothers are characterized to address how host genotype, environmental exposure and host adiposity influence the gut microbiome.
Journal ArticleDOI
The Ribosomal Database Project: improved alignments and new tools for rRNA analysis
James R. Cole,Qiong Wang,Erick Cardenas,Jordan A. Fish,Benli Chai,Ryan J. Farris,A. S. Kulam-Syed-Mohideen,Donna M. McGarrell,Terry L. Marsh,George M. Garrity,James M. Tiedje +10 more
TL;DR: An improved alignment strategy uses the Infernal secondary structure aware aligner to provide a more consistent higher quality alignment and faster processing of user sequences, and a new Pyrosequencing Pipeline that provides tools to support analysis of ultra high-throughput rRNA sequencing data.
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Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns
Maria Gloria Dominguez-Bello,Elizabeth K. Costello,Elizabeth K. Costello,Monica Contreras,Magda Magris,Glida Hidalgo,Noah Fierer,Rob Knight +7 more
TL;DR: It is found that in direct contrast to the highly differentiated communities of their mothers, neonates harbored bacterial communities that were undifferentiated across multiple body habitats, regardless of delivery mode.
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UniFrac--an online tool for comparing microbial community diversity in a phylogenetic context.
TL;DR: Analysis of previously published sequences from the Columbia river, its estuary, and the adjacent coastal ocean using the UniFrac interface provided insights that were not apparent from the initial data analysis, which used other commonly employed techniques to compare the communities.
Journal ArticleDOI
Accurate determination of microbial diversity from 454 pyrosequencing data
Christopher Quince,Anders Lanzén,Thomas P. Curtis,Russell J. Davenport,Neil Hall,Ian M. Head,L Fiona Read,William T. Sloan +7 more
TL;DR: An algorithm is presented, PyroNoise, that clusters the flowgrams of 454 pyrosequencing reads using a distance measure that models sequencing noise and infers the true sequences in a collection of amplicons.
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