Journal ArticleDOI
The neuroendocrinology of obesity
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TLDR
As the nosology of obesity improves, diagnostic efficiency and therapeutic success should increase, leading to a decrease in associated morbidity, mortality, and socioeconomic ramifications.About:
This article is published in Endocrinology and Metabolism Clinics of North America.The article was published on 2001-09-01. It has received 59 citations till now. The article focuses on the topics: Birth weight & Weight loss.read more
Citations
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Psychotropic Drugs in the Treatment of Obesity Promise
TL;DR: Based on the available data for the efficacy of psychotropic agents in obesity and other related conditions, SSRIs may be considered for the management of certain subgroups of obese individuals with comorbid conditions such as depression, binge eating disorder and type 2 diabetes mellitus.
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Contextual Trend in Preventing Obesity Epidemic in Developing Countries: Role of the Key Players
TL;DR: The need for a less cost effective, multi-sectional, far reaching population based intervention plan by the key players of the health sector in developing countries which should incorporate the need for regular exercising, good nutritional habits, body weight image assessment and reduced stigmatization of affected individuals is highlighted.
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Sex-specific effects of prepubertal stress and high-fat diet on leptin signaling in rats
Ana Paula Toniazzo,Danusa Mar Arcego,Camilla Lazzaretti,Carine Lampert,Simone Nardin Weis,Rodrigo Proto-Siqueira,Rachel Krolow,Carla Dalmaz +7 more
TL;DR: Both stress during the prepubertal period and chronic consumption of HFD had long-term sex-specific effects on hormonal signaling related to energy balance, however, the effects of H FD were more pronounced in males, whereas prepuberal stress had greater effects on leptin signaling in females.
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Physical Activity Level of Preschool Children and Their Mothers' Behaviors Promoting Children's Physical Activity
Jin Suk Ra,Chae， SunMi +1 more
TL;DR: Family focused physical activity program for preschool children could be necessary including parental education for improving parental support to increase physical activity level of preschool children.
References
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Positional cloning of the mouse obese gene and its human homologue
Yiying Zhang,Ricardo Proenca,Ricardo Proenca,Margherita Maffei,Marisa Barone,Marisa Barone,Lori Leopold,Lori Leopold,Jeffrey M. Friedman,Jeffrey M. Friedman +9 more
TL;DR: The ob gene product may function as part of a signalling pathway from adipose tissue that acts to regulate the size of the body fat depot.
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Ghrelin is a growth-hormone-releasing acylated peptide from stomach.
TL;DR: The occurrence of ghrelin in both rat and human indicates that GH release from the pituitary may be regulated not only by hypothalamic GHRH, but also by ghrelIn, a peptide specifically releases GH both in vivo and in vitro.
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Central nervous system control of food intake
TL;DR: A model is described that delineates the roles of individual hormonal and neuropeptide signalling pathways in the control of food intake and the means by which obesity can arise from inherited or acquired defects in their function.
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Leptin and the regulation of body weight in mammals
TL;DR: The role of leptin in the control of body weight and its relevance to the pathogenesis of obesity are reviewed.
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Ghrelin induces adiposity in rodents.
TL;DR: It is proposed that ghrelin, in addition to its role in regulating GH secretion, signals the hypothalamus when an increase in metabolic efficiency is necessary, suggesting an involvement in regulation of energy balance.