Journal ArticleDOI
Toxicology of engineered nanomaterials: focus on biocompatibility, biodistribution and biodegradation.
Andrea Kunzmann,Britta Andersson,Tina Thurnherr,Harald F. Krug,Annika Scheynius,Bengt Fadeel +5 more
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TLDR
Understanding the unique characteristics of engineered nanomaterials and their interactions with biological systems is key to the safe implementation of these materials in novel biomedical diagnostics and therapeutics.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 2011-03-01. It has received 460 citations till now. The article focuses on the topics: Nanotoxicology.read more
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Controlling the synthesis and assembly of silver nanostructures for plasmonic applications
Matthew Rycenga,Claire M. Cobley,Jie Zeng,Weiyang Li,Christine H. Moran,Qiang Zhang,Dong Qin,Younan Xia +7 more
TL;DR: In plasmonics, the metal nanostructures can serve as antennas to convert light into localized electric fields (E-fields) or as waveguides to route light to desired locations with nanometer precision through a strong interaction between incident light and free electrons in the nanostructure.
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Engineered Nanoparticles for Drug Delivery in Cancer Therapy
TL;DR: It is anticipated that precisely engineered nanoparticles will emerge as the next-generation platform for cancer therapy and many other biomedical applications.
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Nanotechnological strategies for engineering complex tissues.
TL;DR: The nanocomposite nature of the extracellular matrix is reviewed, the design considerations for different tissues are described, and the impact of nanostructures on the properties of scaffolds and their uses in monitoring the behaviour of engineered tissues are discussed.
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Nanoparticles: a boon to drug delivery, therapeutics, diagnostics and imaging
TL;DR: A comprehensive review on the potential of nanotechnology in medicine focuses on different nanoparticulate drug-delivery systems including polymeric NPs, ceramic Nps, magnetic NPS, polymeric micelles and dendrimers as well as their applications in therapeutics, diagnostics and imaging.
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Understanding biophysicochemical interactions at the nano–bio interface
Andre E. Nel,Lutz Mädler,Darrell Velegol,Tian Xia,Eric M.V. Hoek,Ponisseril Somasundaran,Fred Klaessig,Vince Castranova,Mike Thompson +8 more
TL;DR: Probing the various interfaces of nanoparticle/biological interfaces allows the development of predictive relationships between structure and activity that are determined by nanomaterial properties such as size, shape, surface chemistry, roughness and surface coatings.
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Magnetic nanoparticles: Synthesis, protection, functionalization, and application
TL;DR: This review focuses on the synthesis, protection, functionalization, and application of magnetic nanoparticles, as well as the magnetic properties of nanostructured systems.
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A new class of polymers: Starburst-dendritic macromolecules
Donald A. Tomalia,H. Baker,James R Dewald,Michael B. Hall,G. Kallos,Steven J. Martin,J. Roeck,J. Ryder,Patrick B. Smith +8 more
TL;DR: Starburst polymers as mentioned in this paper are a class of topological macromolecules which are derived from classical monomers/oligomers by their extraordinary symmetry, high branching and maximized terminal functionality density.
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Impact of Nanotechnology on Drug Delivery
TL;DR: This work focuses on the application of nanotechnology to drug delivery and highlights several areas of opportunity where current and emerging nanotechnologies could enable entirely novel classes of therapeutics.
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Understanding the nanoparticle-protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles.
Tommy Cedervall,Iseult Lynch,Stina Lindman,Tord Berggård,Eva Thulin,Hanna Nilsson,Kenneth A. Dawson,Sara Linse +7 more
TL;DR: The rates of protein association and dissociation are determined using surface plasmon resonance technology with nanoparticles that are thiol-linked to gold, and through size exclusion chromatography of protein–nanoparticle mixtures, and this method is developed into a systematic methodology to isolate nanoparticle-associated proteins.