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Journal ArticleDOI

Weighted linear least squares estimation of diffusion MRI parameters: Strengths, limitations, and pitfalls

TLDR
If proper weighting strategies are applied, the weighted linear least squares approach shows high performance characteristics in terms of accuracy/precision and may even be preferred over nonlinear estimation methods.
About
This article is published in NeuroImage.The article was published on 2013-11-01. It has received 403 citations till now. The article focuses on the topics: Generalized least squares & Non-linear least squares.

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Citations
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Journal ArticleDOI

Denoising of diffusion MRI using random matrix theory

TL;DR: A post-processing technique for fast denoising of diffusion-weighted MR images is introduced and it is demonstrated that the technique suppresses local signal fluctuations that solely originate from thermal noise rather than from other sources such as anatomical detail.
Journal ArticleDOI

The challenge of mapping the human connectome based on diffusion tractography

Klaus H. Maier-Hein, +76 more
TL;DR: The encouraging finding that most state-of-the-art algorithms produce tractograms containing 90% of the ground truth bundles (to at least some extent) is reported, however, the same tractograms contain many more invalid than valid bundles, and half of these invalid bundles occur systematically across research groups.
Journal ArticleDOI

Diffusion MRI noise mapping using random matrix theory.

TL;DR: To estimate the spatially varying noise map using a redundant series of magnitude MR images, a random number generator is used to estimate the signal-to- Noise ratio.
References
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Journal ArticleDOI

MR diffusion tensor spectroscopy and imaging.

TL;DR: Once Deff is estimated from a series of NMR pulsed-gradient, spin-echo experiments, a tissue's three orthotropic axes can be determined and the effective diffusivities along these orthotropic directions are the eigenvalues of Deff.
Journal ArticleDOI

Generalized autocalibrating partially parallel acquisitions (GRAPPA).

TL;DR: This technique, GeneRalized Autocalibrating Partially Parallel Acquisitions (GRAPPA) is an extension of both the PILS and VD‐AUTO‐SMASH reconstruction techniques and provides unaliased images from each component coil prior to image combination.
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Estimation of the Effective Self-Diffusion Tensor from the NMR Spin Echo

TL;DR: The diagonal and off-diagonal elements of the effective self-diffusion tensor, Deff, are related to the echo intensity in an NMR spin-echo experiment.
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Toward a quantitative assessment of diffusion anisotropy

TL;DR: New indices calculated from the entire diffusion tensor are rotationally invariant (RI) and show that anisotropy is highly variable in different white matter regions depending on the degree of coherence of fiber tract directions.
Journal ArticleDOI

Diffusional kurtosis imaging: The quantification of non-gaussian water diffusion by means of magnetic resonance imaging

TL;DR: From the study of six healthy adult subjects, the excess diffusional kurtosis is found to be significantly higher in white matter than in gray matter, reflecting the structural differences between these two types of cerebral tissues.
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