Wireless, battery-free optoelectronic systems as subdermal implants for local tissue oximetry.
Hao Zhang,Philipp Gutruf,Philipp Gutruf,Kathleen Meacham,Michael C. Montana,Xingyue Zhao,Xingyue Zhao,Antonio Maria Chiarelli,Abraham Vázquez-Guardado,Aaron J. Norris,Luyao Lu,Qinglei Guo,Qinglei Guo,Chenkai Xu,Yixin Wu,Hangbo Zhao,Xin Ning,Wubin Bai,Irawati Kandela,Chad R. Haney,Debashis Chanda,Robert W. Gereau,John A. Rogers +22 more
TLDR
An entirely wireless and fully implantable platform incorporating microscale optoelectronics for continuous sensing of local hemoglobin dynamics and advanced designs in continuous, wireless power delivery and data output for tether-free operation is introduced.Abstract:
Monitoring regional tissue oxygenation in animal models and potentially in human subjects can yield insights into the underlying mechanisms of local O2-mediated physiological processes and provide diagnostic and therapeutic guidance for relevant disease states. Existing technologies for tissue oxygenation assessments involve some combination of disadvantages in requirements for physical tethers, anesthetics, and special apparatus, often with confounding effects on the natural behaviors of test subjects. This work introduces an entirely wireless and fully implantable platform incorporating (i) microscale optoelectronics for continuous sensing of local hemoglobin dynamics and (ii) advanced designs in continuous, wireless power delivery and data output for tether-free operation. These features support in vivo, highly localized tissue oximetry at sites of interest, including deep brain regions of mice, on untethered, awake animal models. The results create many opportunities for studying various O2-mediated processes in naturally behaving subjects, with implications in biomedical research and clinical practice.read more
Citations
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Multifunctional materials for implantable and wearable photonic healthcare devices.
Geon-Hui Lee,Geon-Hui Lee,Hanul Moon,Hanul Moon,Hyemin Kim,Gae Hwang Lee,Gae Hwang Lee,Woosung Kwon,Seunghyup Yoo,David Myung,Seok Hyun Yun,Zhenan Bao,Sei Kwang Hahn,Sei Kwang Hahn +13 more
TL;DR: This Review describes emerging multifunctional materials critical to the advent of next-generation implantable and wearable photonic healthcare devices and discusses the path for their clinical translation, along with the future research directions for the field, particularly regarding mobile healthcare and personalized medicine.
Journal ArticleDOI
Mechanically-Guided Structural Designs in Stretchable Inorganic Electronics.
TL;DR: The diverse structural geometries developed for stretchable inorganic electronics are summarized, covering the designs of functional devices and soft substrates, with a focus on fundamental principles, design approaches, and system demonstrations.
Journal ArticleDOI
Wireless battery-free body sensor networks using near-field-enabled clothing
Rongzhou Lin,Han-Joon Kim,Sippanat Achavananthadith,Selman A. Kurt,Shawn Tan,Haicheng Yao,Benjamin C. K. Tee,Jason Kai Wei Lee,John S. Ho +8 more
TL;DR: Near-field-enabled clothing capable of establishing wireless power and data connectivity between multiple distant points around the body to create a network of battery-free sensors interconnected by proximity to functional textile patterns is reported.
Journal ArticleDOI
Tissue-like skin-device interface for wearable bioelectronics by using ultrasoft, mass-permeable, and low-impedance hydrogels.
Chanhyuk Lim,Yongseok Joseph Hong,Jaebong Jung,Yoonsoo Shin,Sung-Hyuk Sunwoo,Seungmin Baik,Ok Kyu Park,Ok Kyu Park,Sueng Hong Choi,Sueng Hong Choi,Taeghwan Hyeon,Ji-Hoon Kim,Sang-Kyu Lee,Dae-Hyeong Kim +13 more
TL;DR: In this paper, an ultrathin type of functionalized hydrogel was used as a liquid electrolyte on the skin and formed an extremely conformal and low-impedance interface for wearable electrochemical biosensors and electrical stimulators.
Journal ArticleDOI
Recent Progress in Wireless Sensors for Wearable Electronics.
TL;DR: This review article discusses recent progress in wireless technologies and various types of wearable sensors, including electronic skin, smart contact lenses, neural interfaces, and retinal prostheses.
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