Within-subject variation of seminal parameters in men with infertile marriages.
Felice Francavilla,Arcangelo Barbonetti,Stefano Necozione,R. Santucci,Giuliana Cordeschi,B. Macerola,Sandro Francavilla +6 more
TLDR
In 253 cycles of double IUI, performed in two consecutive days, semen volume and parameters including volume decreased in the second sample, but semen quality improved in most cases of oligo- and/or asthenozoospermia.Abstract:
As little information exists on the semen variability in infertile men, this study aimed at analysing the within-subject variability of semen from men with infertile marriages included in an intrauterine insemination (IUI) programme. Five ejaculates from each of 436 men (2180 specimens) were analysed. The within-subject coefficients of variation (CV(w)) were high for all parameters (semen volume, sperm concentration, forward motility and combined parameters), ranging from 0.73 for the total motile sperm count to 0.27 for the semen volume. Nevertheless, within-subject fluctuations were smaller than the between-subject variability, as indicated by high Intraclass Correlation Coefficient (ICC) values, which, however, significantly lowered when <or=3 samples were analysed against five samples. Neither seasonality nor the length of abstinence between 3 and 7 days significantly affected within-subject semen variability, whereas total motile sperm count was significantly and negatively affected at 2 days of abstinence. In 253 cycles of double IUI, performed in two consecutive days, semen volume and parameters including volume decreased in the second sample, but semen quality improved in most cases of oligo- and/or asthenozoospermia. Useful information for clinical purposes is provided.read more
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Semen quality and sperm DNA damage in relation to urinary bisphenol A among men from an infertility clinic.
John D. Meeker,Shelley Ehrlich,Thomas L. Toth,Diane L. Wright,Antonia M. Calafat,Ana T. Trisini,Xiaoyun Ye,Russ Hauser +7 more
TL;DR: Urinary BPA may be associated with declined semen quality and increased sperm DNA damage, but confirmatory studies are needed.
Journal ArticleDOI
The diagnosis of male infertility: an analysis of the evidence to support the development of global WHO guidance—challenges and future research opportunities
Christopher L.R. Barratt,Lars Björndahl,Christopher J. De Jonge,Dolores J. Lamb,Francisco Osorio Martini,Robert I McLachlan,Robert D. Oates,Sheryl van der Poel,Sheryl van der Poel,Bianca St John,Mark Sigman,Rebecca Z. Sokol,Herman Tournaye +12 more
TL;DR: The consensus guideline methodology is described, the evidence-based recommendations provided to the World Health Organization for their consideration in the development of global guidance are summarized and a narrative review of the diagnosis of male infertility as related to the eight prioritized PICO questions is presented.
Journal ArticleDOI
Cadmium, lead, and other metals in relation to semen quality: human evidence for molybdenum as a male reproductive toxicant.
John D. Meeker,M.G. Rossano,Bridget Protas,Michael P. Diamond,Elizabeth E. Puscheck,Douglas C. Daly,Nigel Paneth,Julia J. Wirth +7 more
TL;DR: These findings represent the first human evidence for an inverse association between Mo and semen quality and are consistent with animal data, but additional human and mechanistic studies are needed.
Journal ArticleDOI
European Academy of Andrology guideline Management of oligo-astheno-teratozoospermia.
Giovanni M. Colpi,Sandro Francavilla,Gerhard Haidl,Katarina Link,Hermann M. Behre,Dimitrios G. Goulis,Csilla Krausz,Aleksander Giwercman +7 more
TL;DR: The aim of this European Academy of Andrology guideline was to provide an overview of factors contributing toligo‐astheno‐teratozoospermia and to discuss available management options.
Journal ArticleDOI
Semen quality of young adult ICSI offspring: the first results.
F Belva,Mary-Louise Bonduelle,Mathieu Roelants,Dirk Michielsen,A. Van Steirteghem,G. Verheyen,H. Tournaye +6 more
TL;DR: A large follow-up project focussing on reproductive and metabolic health of young adults, between 18 and 22 years and conceived after ICSI with ejaculated sperm, finds that median sperm concentration, total sperm count and total motile sperm count were significantly lower than in spontaneously conceived peers.
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Journal ArticleDOI
Relationship between the duration of sexual abstinence and semen quality: analysis of 9,489 semen samples
Eliahu Levitas,Eitan Lunenfeld,Noemi Weiss,Michael Friger,Iris Har-Vardi,Arie Koifman,Gad Potashnik +6 more
TL;DR: It is suggested that to present the best possible semen samples, patients with male factor infertility should collect the semen after just 1 day of sexual abstinence and patients presenting normal sperm analysis or sperm donors for cryopreservation purposes should be advised not to exceed 10 days ofSexual abstinence.
Journal ArticleDOI
Within-subject variability of human semen in regard to sperm count, volume, total number of spermatozoa and length of abstinence
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