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Andreas Strasser
Researcher at Walter and Eliza Hall Institute of Medical Research
Publications - 537
Citations - 75592
Andreas Strasser is an academic researcher from Walter and Eliza Hall Institute of Medical Research. The author has contributed to research in topics: Apoptosis & Programmed cell death. The author has an hindex of 128, co-authored 509 publications receiving 66903 citations. Previous affiliations of Andreas Strasser include University of Alabama at Birmingham & Basel Institute for Immunology.
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Bim must be able to engage all pro-survival Bcl-2 family members for efficient tumor suppression
TL;DR: It is demonstrated that for optimal tumor suppressive activity, Bim must be able to interact with all and not just select pro-survival Bcl-2 family members.
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Caspase-8 Inactivation in T Cells Increases Necroptosis and Suppresses Autoimmunity in \(Bim^{−/−}\) Mice
Toshiyuki Bohgaki,Julien Mozo,Leonardo Salmena,Elzbieta Matysiak-Zablocki,Miyuki Bohgaki,Otto Sanchez,Andreas Strasser,Anne Hakem,Razqallah Hakem +8 more
TL;DR: In the absence of the pro-apoptotic factor Bim, caspase-8 plays an important role in restraining autoimmunity by inducing cell death in T cells.
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Dr. Josef Steiner Cancer Research Prize Lecture: the role of physiological cell death in neoplastic transformation and in anti-cancer therapy.
TL;DR: Findings from cell death research should provide clues for designing therapies for a variety of diseases, including degenerative disorders, auto‐immunity and cancer.
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Dynein light chain regulates adaptive and innate B cell development by distinctive genetic mechanisms.
Ashleigh King,Ashleigh King,Lingli Li,Lingli Li,David M. Wong,Rui Liu,Rebecca Bamford,Andreas Strasser,Andreas Strasser,David M. Tarlinton,Jörg Heierhorst,Jörg Heierhorst +11 more
TL;DR: These results identify ASCIZ and DYNLL1 as the core of a transcriptional circuit that differentially regulates the development of the B-1a and B-2 B lymphoid cell lineages and plays a critical role in lymphomagenesis.
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A decade of molecular cell biology: achievements and challenges
Asifa Akhtar,Elaine Fuchs,Timothy J. Mitchison,Reuben J. Shaw,Daniel St Johnston,Andreas Strasser,Susan S. Taylor,Claire E. Walczak,Marino Zerial +8 more
TL;DR: Researchers from across the field have been asked for their insights into how molecular cell biology research has evolved during this past decade, the key concepts that have emerged and the most promising interfaces that have developed.