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Bart De Strooper
Researcher at Katholieke Universiteit Leuven
Publications - 433
Citations - 56592
Bart De Strooper is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Amyloid precursor protein & Presenilin. The author has an hindex of 117, co-authored 397 publications receiving 48516 citations. Previous affiliations of Bart De Strooper include Ghent University & Allen Institute for Brain Science.
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The A-beta 42/40 ratio is a driver of acute synaptotoxicity and LTP impairment
Iryna Benilova,Seon-Ah Chong,Inna Kuperstein,Kerensa Broersen,Joost Schymkowitz,Frederic Rousseau,Carmen Bartic,Geert Callewaert,Bart De Strooper +8 more
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Mir-132: promoting adult neurogenesis in alzheimer’s disease
TL;DR: This study proposes to explore and validate miRNAs that have directly or indirectly relations to the AD pathophysiology and ADAM10 gene expression, and finds that Mir-144-5p, miR-374 and mi R-221 are downregulated in AD subjects compared to healthy controls, with moderate accuracy diagnosis.
Posted ContentDOI
The Amyloid Precursor Protein is a conserved Wnt receptor
Tengyuan Liu,Maya Nicolas,Tingting Zhang,Heather C. Rice,Alessia Soldano,Annelies Claeys,Iveta M. Petrova,Lee G. Fradkin,Bart De Strooper,Bassem A. Hassan +9 more
TL;DR: In this paper, it was shown that APP binds the Wnt ligands Wnt3a and Wnt5a and that this binding regulates APP protein levels and promotes full-length APP (flAPP) recycling and stability.
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P1-457: Neuronal differentiation of APP/APLP1/APLP2 triple knockout (tKO) embryonic stem (ES) cells
Bruno Bergmans,Ron L. P. Habets,Patrik Verstreken,Carlos G. Dotti,Ulrike Müller,Bart De Strooper +5 more