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Chen-Yang Shen
Researcher at Academia Sinica
Publications - 168
Citations - 19120
Chen-Yang Shen is an academic researcher from Academia Sinica. The author has contributed to research in topics: Breast cancer & Single-nucleotide polymorphism. The author has an hindex of 57, co-authored 166 publications receiving 17287 citations. Previous affiliations of Chen-Yang Shen include University of Hamburg & China Medical University (PRC).
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Journal ArticleDOI
Hantavirus infection in Taiwan.
Journal ArticleDOI
7q21-rs6964587 and breast cancer risk: An extended case-control study by the Breast Cancer Association Consortium
Roger L. Milne,Justo Lorenzo-Bermejo,Justo Lorenzo-Bermejo,Barbara Burwinkel,Barbara Burwinkel,Núria Malats,José Ignacio Arias,M. Pilar Zamora,Javier Benitez,Manjeet K. Humphreys,Montserrat Garcia-Closas,Stephen J. Chanock,Jolanta Lissowska,Mark E. Sherman,Arto Mannermaa,Vesa Kataja,Veli-Matti Kosma,Heli Nevanlinna,Tuomas Heikkinen,Kristiina Aittomäki,Carl Blomqvist,Hoda Anton-Culver,Argyrios Ziogas,Peter Devilee,Christie J. van Asperen,Rob A. E. M. Tollenaar,Caroline Seynaeve,Per Hall,Kamila Czene,Jianjun Liu,Astrid K. Irwanto,Daehee Kang,Keun-Young Yoo,Dong Young Noh,Fergus J. Couch,Janet E. Olson,Xianshu Wang,Zachary S. Fredericksen,Børge G. Nordestgaard,Stig E. Bojesen,Henrik Flyger,Sara Margolin,Annika Lindblom,Peter A. Fasching,Peter A. Fasching,Ruediger Schulz-Wendtland,Arif B. Ekici,Matthias W. Beckmann,Shan Wang-Gohrke,Chen-Yang Shen,Jyh Cherng Yu,Huan Ming Hsu,Pei Ei Wu,Graham G. Giles,Gianluca Severi,Laura Baglietto,Dallas R. English,Angela Cox,Ian W. Brock,Graeme Elliott,Malcolm W.R. Reed,Jonathan Beesley,Xiaoqing Chen,Olivia Fletcher,Lorna Gibson,Isabel dos Santos Silva,Julian Peto,Bernd Frank,Joerg Heil,Alfons Meindl,Jenny Chang-Claude,Rebecca Hein,Alina Vrieling,Dieter Flesch-Janys,Melissa C. Southey,Letitia D. Smith,Carmel Apicella,John L. Hopper,Alison M. Dunning,Karen A. Pooley,Paul D.P. Pharoah,Ute Hamann,Beate Pesch,Yon Ko,Douglas F. Easton,Georgia Chenevix-Trench +85 more
TL;DR: This may be the first common susceptibility allele for breast cancer to be identified with a recessive mode of inheritance.
Journal ArticleDOI
New Breast Cancer Risk Variant Discovered at 10q25 in East Asian Women
Jiajun Shi,Hyuna Sung,Ben Zhang,Wei Lu,Ji-Yeob Choi,Yong-Bing Xiang,Mi Kyung Kim,Motoki Iwasaki,Jirong Long,Bu Tian Ji,Sue K. Park,Ying Zheng,Shoichiro Tsugane,Keun-Young Yoo,Wenjing Wang,Dong Young Noh,Wonshik Han,Sung Won Kim,Min Hyuk Lee,Jong Won Lee,Jong-Young Lee,Chen-Yang Shen,Keitaro Matsuo,Sei Hyun Ahn,Yu-Tang Gao,Xiao-Ou Shu,Qiuyin Cai,Daehee Kang,Wei Zheng +28 more
TL;DR: In this article, the authors evaluated nine non-replication loci in East Asians in order to identify new risk variants for breast cancer in these regions and identified a new breast cancer risk variant at 10q25 in East Asian women.
Journal ArticleDOI
SUMOylation of XRCC1 activated by poly (ADP-ribosyl)ation regulates DNA repair
Ling Yueh Hu,Che Chang Chang,Yen Sung Huang,Wen Cheng Chou,Ying Mei Lin,Chun Chen Ho,Wei-Ting Chen,Hsiu Ming Shih,Hsiu Ming Shih,Chia-Ni Hsiung,Pei Ei Wu,Chen-Yang Shen,Chen-Yang Shen +12 more
TL;DR: A pathway in which DNA damage-induced poly(ADP-ribosyl)ation (PARylation) promotes SUMOylation of XRCC1, which leads to more efficient recruitment of POLB to complete BER.