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Ben Zhang
Researcher at Vanderbilt University Medical Center
Publications - 7
Citations - 327
Ben Zhang is an academic researcher from Vanderbilt University Medical Center. The author has contributed to research in topics: Genome-wide association study & Breast cancer. The author has an hindex of 5, co-authored 7 publications receiving 252 citations. Previous affiliations of Ben Zhang include Third Military Medical University.
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Journal ArticleDOI
Genome-wide association study of colorectal cancer identifies six new susceptibility loci
Fredrick R. Schumacher,Stephanie L. Schmit,Shuo Jiao,Christopher K. Edlund,Hansong Wang,Ben Zhang,Li Hsu,Shu Chen Huang,Christopher P. Fischer,John F. Harju,Gregory Idos,Flavio Lejbkowicz,Frank J. Manion,Kevin McDonnell,Caroline McNeil,Marilena Melas,Hedy S. Rennert,Wei Shi,Duncan C. Thomas,David Van Den Berg,Carolyn M. Hutter,Aaron K. Aragaki,Katja Butterbach,Bette J. Caan,Christopher S. Carlson,Stephen J. Chanock,Keith R. Curtis,Charles S. Fuchs,Manish Gala,Edward L. Giocannucci,Stephanie M. Gogarten,Richard B. Hayes,Brian E. Henderson,David J. Hunter,Rebecca D. Jackson,Laurence N. Kolonel,Charles Kooperberg,Sebastian Kury,Andrea Z. LaCroix,Cathy C. Laurie,Cecelia A. Laurie,Mathiew Lemire,David K. Levine,Jing Ma,Karen W. Makar,Conghui Qu,Darin Taverna,Cornelia M. Ulrich,Cornelia M. Ulrich,Cornelia M. Ulrich,Kana Wu,Suminori Kono,Dee W. West,Sonja I. Berndt,Stéphane Bézieau,Hermann Brenner,Peter T. Campbell,Andrew T. Chan,Jenny Chang-Claude,Gerhard A. Coetzee,David V. Conti,David Duggan,Jane C. Figueiredo,Barbara K. Fortini,Steven Gallinger,W. James Gauderman,Graham G. Giles,Roger C. Green,Robert W. Haile,Tabitha A. Harrison,Michael Hoffmeister,John L. Hopper,Thomas J. Hudson,Eric J. Jacobs,Motoki Iwasaki,Sun Ha Jee,Mark A. Jenkins,Wei Hua Jia,Amit Joshi,Li Li,N. M. Lindor,Keitaro Matsuo,Victor Moreno,Bhramar Mukherjee,Polly A. Newcomb,John D. Potter,Leon Raskin,Leon Raskin,Gad Rennert,Stephanie A. Rosse,Gianluca Severi,Robert E. Schoen,Daniela Seminara,Xiao-Ou Shu,Martha L. Slattery,Shoichiro Tsugane,Emily White,Yong-Bing Xiang,Brent W. Zanke,Wei Zheng,Loic Le Marchand,Graham Casey,Stephen B. Gruber,Ulrike Peters +103 more
TL;DR: Six new susceptibility loci reaching a genome-wide threshold of P<5.0E-08 are described, providing additional insight into the underlying biological mechanisms of colorectal cancer and demonstrating the scientific value of large consortia-based genetic epidemiology studies.
Journal ArticleDOI
Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer.
Yingchang Lu,Sun-Seog Kweon,Chizu Tanikawa,Wei Hua Jia,Yong-Bing Xiang,Qiuyin Cai,Chenjie Zeng,Stephanie L. Schmit,Aesun Shin,Keitaro Matsuo,Sun Ha Jee,Dong Hyun Kim,Jeongseon Kim,Wanqing Wen,Jiajun Shi,Xingyi Guo,Bingshan Li,Nan Wang,Ben Zhang,Xinxiang Li,Min-Ho Shin,Hong Lan Li,Zefang Ren,Jae Hwan Oh,Isao Oze,Yoon Ok Ahn,Keum Ji Jung,David V. Conti,Fredrick R. Schumacher,Gad Rennert,Mark A. Jenkins,Peter T. Campbell,Michael Hoffmeister,Graham Casey,Stephen B. Gruber,Jing Gao,Yu-Tang Gao,Zhi Zhong Pan,Yoichiro Kamatani,Yi Xin Zeng,Xiao-Ou Shu,Jirong Long,Koichi Matsuda,Wei Zheng +43 more
TL;DR: A genome-wide association study of East Asians showed that most of the risk loci previously associated with CRC risk in individuals of European descent were also associated with colorectal cancer risk in East Asians.
Journal ArticleDOI
Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium
Roger L. Milne,Roger L. Milne,Barbara Burwinkel,Kyriaki Michailidou,Jose-Ignacio Arias-Perez,M. Pilar Zamora,Primitiva Menendez-Rodriguez,David Hardisson,Marta Mendiola,Anna González-Neira,Guillermo Pita,M. Rosario Alonso,Joe Dennis,Qin Wang,Manjeet K. Bolla,Anthony J. Swerdlow,Anthony J. Swerdlow,Alan Ashworth,Nick Orr,Minouk J. Schoemaker,Yon-Dschun Ko,Hiltrud Brauch,Hiltrud Brauch,Ute Hamann,Irene L. Andrulis,Julia A. Knight,Julia A. Knight,Gord Glendon,Sandrine Tchatchou,kConFab Investigators,Keitaro Matsuo,Hidemi Ito,Hiroji Iwata,Kazuo Tajima,Jingmei Li,Judith S. Brand,Hermann Brenner,Aida Karina Dieffenbach,Volker Arndt,Christa Stegmaier,Diether Lambrechts,Gilian Peuteman,Marie-Rose Christiaens,Ann Smeets,Anna Jakubowska,Jan Lubinski,Katarzyna Jaworska-Bieniek,Katazyna Durda,Mikael Hartman,Miao Hui,Wei-Yen Lim,Ching Wan Chan,Federick Marme,Rongxi Yang,Peter Bugert,Annika Lindblom,Sara Margolin,Montserrat Garcia-Closas,Stephen J. Chanock,Jolanta Lissowska,Jonine D. Figueroa,Stig E. Bojesen,Stig E. Bojesen,Børge G. Nordestgaard,Børge G. Nordestgaard,Henrik Flyger,Maartje J. Hooning,Mieke Kriege,Ans M.W. van den Ouweland,Linetta B. Koppert,Olivia Fletcher,Nichola Johnson,Isabel dos-Santos-Silva,Julian Peto,Wei Zheng,Sandra Deming-Halverson,Martha J. Shrubsole,Jirong Long,Jenny Chang-Claude,Anja Rudolph,Petra Seibold,Dieter Flesch-Janys,Robert Winqvist,Katri Pylkäs,Arja Jukkola-Vuorinen,Mervi Grip,Angela Cox,Simon S. Cross,Malcolm W.R. Reed,Marjanka K. Schmidt,Annegien Broeks,Sten Cornelissen,Linde M. Braaf,Daehee Kang,Ji Yeob Choi,Sue K. Park,Dong-Young Noh,Jacques Simard,Martine Dumont,Mark S. Goldberg,Mark S. Goldberg,Peter A. Fasching,Alexander Hein,Arif B. Ekici,Matthias W. Beckmann,Paolo Radice,Paolo Peterlongo,Jacopo Azzollini,Monica Barile,Elinor J. Sawyer,Ian Tomlinson,Ian Tomlinson,Michael J. Kerin,Nicola Miller,John L. Hopper,Daniel F. Schmidt,Enes Makalic,Melissa C. Southey,Soo Hwang Teo,Cheng Har Yip,Kavitta Sivanandan,Wan Ting Tay,Chen-Yang Shen,Chen-Yang Shen,Chia-Ni Hsiung,Jyh-Cherng Yu,Ming-Feng Hou,Pascal Guénel,Thérèse Truong,Marie Sanchez,Claire Mulot,William Blot,Qiuyin Cai,Heli Nevanlinna,Taru A. Muranen,Kristiina Aittomäki,Carl Blomqvist,Anna H. Wu,Chiu-Chen Tseng,David Van Den Berg,Daniel O. Stram,Natalia Bogdanova,Thilo Dörk,Kenneth Muir,Kenneth Muir,Artitaya Lophatananon,Sarah Stewart-Brown,Pornthep Siriwanarangsan,Arto Mannermaa,Vesa Kataja,Veli-Matti Kosma,Jaana M. Hartikainen,Xiao-Ou Shu,Wei Lu,Yu Tang Gao,Ben Zhang,Fergus J. Couch,Amanda E. Toland,Tnbcc,Drakoulis Yannoukakos,Suleeporn Sangrajrang,James McKay,Xianshu Wang,Janet E. Olson,Celine M. Vachon,Kristen S. Purrington,Gianluca Severi,Gianluca Severi,Laura Baglietto,Laura Baglietto,Christopher A. Haiman,Brian E. Henderson,Fredrick R. Schumacher,Loic Le Marchand,Peter Devilee,Robert A.E.M. Tollenaar,Caroline M. Seynaeve,Kamila Czene,Mikael Eriksson,Keith Humphreys,Hatef Darabi,Shahana Ahmed,Mitul Shah,Paul D.P. Pharoah,Per Hall,Graham G. Giles,Graham G. Giles,Javier Benitez,Alison M. Dunning,Georgia Chenevix-Trench,Douglas F. Easton +190 more
TL;DR: A novel susceptibility locus at 3p21 is identified, and previous suggestive evidence that rs6964587 at 7q21 is associated with risk is confirmed, and further fine-mapping and functional studies are required to identify the underlying risk-modifying variants and the genes through which they act.
Journal ArticleDOI
Association of type 2 diabetes genetic variants with breast cancer survival among Chinese women.
Ping-Ping Bao,Zhiguo Zhao,Yu-Tang Gao,Ying Zheng,Ben Zhang,Hui Cai,Wei Zheng,Xiao-Ou Shu,Wei Lu +8 more
TL;DR: It is suggested that genetic susceptibility of T2D was positively associated with total mortality among women with ER- breast cancer, particularly among subjects with a history of diabetes.
Journal ArticleDOI
New Breast Cancer Risk Variant Discovered at 10q25 in East Asian Women
Jiajun Shi,Hyuna Sung,Ben Zhang,Wei Lu,Ji-Yeob Choi,Yong-Bing Xiang,Mi Kyung Kim,Motoki Iwasaki,Jirong Long,Bu Tian Ji,Sue K. Park,Ying Zheng,Shoichiro Tsugane,Keun-Young Yoo,Wenjing Wang,Dong Young Noh,Wonshik Han,Sung Won Kim,Min Hyuk Lee,Jong Won Lee,Jong-Young Lee,Chen-Yang Shen,Keitaro Matsuo,Sei Hyun Ahn,Yu-Tang Gao,Xiao-Ou Shu,Qiuyin Cai,Daehee Kang,Wei Zheng +28 more
TL;DR: In this article, the authors evaluated nine non-replication loci in East Asians in order to identify new risk variants for breast cancer in these regions and identified a new breast cancer risk variant at 10q25 in East Asian women.