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Cornelius Engelmann
Researcher at University College London
Publications - 65
Citations - 1312
Cornelius Engelmann is an academic researcher from University College London. The author has contributed to research in topics: Cirrhosis & Medicine. The author has an hindex of 11, co-authored 42 publications receiving 577 citations. Previous affiliations of Cornelius Engelmann include Leipzig University & Aarhus University Hospital.
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Journal ArticleDOI
The PREDICT study uncovers three clinical courses of acutely decompensated cirrhosis that have distinct pathophysiology.
Jonel Trebicka,Javier J.M. Fernández,Mária Papp,Paolo Caraceni,Wim Laleman,Carmine Gambino,Ilaria Giovo,Frank Erhard Uschner,Cesar Jimenez,Rajeshwar P. Mookerjee,Thierry Gustot,Agustín Albillos,Rafael Bañares,Martin Janicko,Christian J. Steib,Thomas Reiberger,Juan Acevedo,Pietro Gatti,William Bernal,Stefan Zeuzem,Alexander Zipprich,Salvatore Piano,Thomas Berg,Tony Bruns,Flemming Bendtsen,Minneke J. Coenraad,Manuela Merli,Rudolf E. Stauber,Heinz Zoller,Jose Presa Ramos,Cristina Solé,Germán Soriano,Andrea De Gottardi,Henning Grønbæk,Faouzi Saliba,Christian Trautwein,Osman Ozdogan,Sven Francque,Stephen D. Ryder,Pierre Nahon,Manuel Romero-Gómez,Hans Van Vlierberghe,Claire Francoz,Michael Manns,Elisabet Garcia,Manuel Tufoni,Alex Amoros,Marco Pavesi,Cristina Sanchez,Anna Curto,Carla Pitarch,Antonella Putignano,Esau Moreno,Debbie L. Shawcross,Ferran Aguilar,Joan Clària,Paola Ponzo,Christian Jansen,Zsuzsanna Vitális,Giacomo Zaccherini,Boglarka Balogh,Victor Vargas,Sara Montagnese,Carlo Alessandria,Mauro Bernardi,Pere Ginès,Rajiv Jalan,Richard Moreau,Paolo Angeli,Vicente Arroyo,Miriam Maschmeier,David Semela,Laure Elkrief,Ahmed Elsharkawy,Tamas Tornai,István Tornai,István Altorjay,Agnese Antognoli,Maurizio Baldassarre,Martina Gagliardi,Eleonora Bertoli,Sara Mareso,Alessandra Brocca,Daniela Campion,Giorgio Maria Saracco,Martina Rizzo,Jennifer Lehmann,Alessandra Pohlmann,Michael Praktiknjo,Robert Schierwagen,Robert Schierwagen,Elsa Solà,Nesrine Amari,Miguel Á. Rodríguez,Frederik Nevens,Ana Clemente,Peter Jarcuska,Alexander L. Gerbes,Mattias Mandorfer,Christoph Welsch,Emanuela Ciraci,Vish Patel,Cristina Ripoll,Adam Herber,Paul Horn,Karen Vagner Danielsen,Lise Lotte Gluud,Jelte J Schaapman,Oliviero Riggio,Florian Rainer,Jörg Tobiasch Moritz,Monica Mesquita,Edilmar Alvarado-Tapias,Osagie Akpata,Peter Lykke Eriksen,Didier Samuel,Sylvie Tresson,Pavel Strnad,Roland Amathieu,Macarena Simón-Talero,Francois Smits,Natalie Van den Ende,Javier Martínez,Rita Garcia,Daniel Markwardt,Harald Rupprechter,Cornelius Engelmann +126 more
TL;DR: Acute decompensation without ACLF is a heterogeneous condition with three different clinical courses and two major pathophysiological mechanisms: systemic inflammation and portal hypertension.
Journal ArticleDOI
Antithrombotic treatment with direct-acting oral anticoagulants in patients with splanchnic vein thrombosis and cirrhosis
Andrea De Gottardi,Jonel Trebicka,Christoph Klinger,Aurélie Plessier,Susana Seijo,B. Terziroli,Lorenzo Magenta,David Semela,Elisabetta Buscarini,Philippe Langlet,Jan Görtzen,Angela Puente,Beat Müllhaupt,Carmen A. Navascués,Filipe Nery,Pierre Deltenre,Fanny Turon,Cornelius Engelmann,Rupen Arya,Karel Caca,Markus Peck-Radosavljevic,Frank W.G. Leebeek,D. Valla,Juan Carlos García-Pagán +23 more
TL;DR: The aim was to identify indications and reasons for starting or switching to DOACs and to report adverse effects, complications and short‐term outcome.
Journal ArticleDOI
PREDICT identifies precipitating events associated with the clinical course of acutely decompensated cirrhosis
Jonel Trebicka,Javier Romaní Fernández,Mária Papp,Paolo Caraceni,Wim Laleman,Carmine Gambino,Ilaria Giovo,Frank Erhard Uschner,Christian Jansen,Cesar Jimenez,Rajeshwar P. Mookerjee,Thierry Gustot,Agustín Albillos,Rafael Bañares,Peter Jarcuska,Christian J. Steib,Thomas Reiberger,Juan Acevedo,Pietro Gatti,Debbie L. Shawcross,Stefan Zeuzem,Alexander Zipprich,Salvatore Piano,Thomas Berg,Tony Bruns,Karen Vagner Danielsen,Minneke J. Coenraad,Manuela Merli,Rudolf E. Stauber,Heinz Zoller,Jose Presa Ramos,Cristina Solé,Germán Soriano,Andrea De Gottardi,Henning Grønbæk,Faouzi Saliba,Christian Trautwein,Haluk Tarik Kani,Sven Francque,Stephen D. Ryder,Pierre Nahon,Pierre Nahon,Manuel Romero-Gómez,Hans Van Vlierberghe,Claire Francoz,Michael Manns,Elisabet Garcia-Lopez,Manuel Tufoni,Alex Amoros,Marco Pavesi,Cristina Sanchez,Michael Praktiknjo,Anna Curto,Carla Pitarch,Antonella Putignano,Esau Moreno,William Bernal,Ferran Aguilar,Joan Clària,Paola Ponzo,Zsuzsanna Vitális,Giacomo Zaccherini,Boglarka Balogh,Alexander L. Gerbes,Victor Vargas,Carlo Alessandria,Mauro Bernardi,Pere Ginès,Richard Moreau,Paolo Angeli,Rajiv Jalan,Vicente Arroyo,Miriam Maschmeier,David Semela,Laure Elkrief,Ahmed Elsharkawy,Tamas Tornai,István Tornai,István Altorjay,Agnese Antognoli,Maurizio Baldassarre,Martina Gagliardi,Eleonora Bertoli,Sara Mareso,Alessandra Brocca,Daniela Campion,Giorgio Maria Saracco,Martina Rizzo,Jennifer Lehmann,Alessandra Pohlmann,Maximilian J. Brol,Johannes Chang,Robert Schierwagen,Elsa Solà,Nesrine Amari,Miguel Á. Rodríguez,Frederik Nevens,Ana Clemente,Martin Janicko,Daniel Markwardt,Mattias Mandorfer,Christoph Welsch,T.M. Welzel,Emanuela Ciraci,Vish Patel,Cristina Ripoll,Adam Herber,Paul Horn,Flemming Bendtsen,Lise Lotte Gluud,Jelte J Schaapman,Oliviero Riggio,Florian Rainer,Joerg Tobiasch Moritz,Monica Mesquita,Edilmar Alvarado-Tapias,Osagie Akpata,Luise Aamann,Didier Samuel,Sylvie Tresson,Pavel Strnad,Roland Amathieu,Roland Amathieu,Macarena Simón-Talero,Francois Smits,Natalie Van den Ende,Javier Martínez,Rita Garcia,Harald Rupprechter,Cornelius Engelmann,Osman Ozdogan +130 more
TL;DR: This study identified precipitants that are significantly associated with a distinct clinical course and prognosis of patients with AD and specific preventive and therapeutic strategies targeting these events may improve outcome in decompensated cirrhosis.
Journal ArticleDOI
Validation of CLIF-C ACLF score to define a threshold for futility of intensive care support for patients with acute-on-chronic liver failure
Cornelius Engelmann,Karen Louise Thomsen,Karen Louise Thomsen,Nekisa Zakeri,Mohammed Sheikh,Banwari Agarwal,Banwari Agarwal,Rajiv Jalan,Rajeshwar P. Mookerjee +8 more
TL;DR: Patients with ACLF and high CLIF-C ACLF score after 48 hours of intensive care may reach a threshold of futility for further ongoing intensive support, and the best treatment options in this scenario remain to be determined but may include palliative care.
Journal ArticleDOI
Effect of sarcopenia on survival in patients with cirrhosis: A systematic review and meta-analysis.
Xinxing Tantai,Fanpu Ji,Yi Liu,Yee Hui Yeo,Michael Praktiknjo,Ezequiel Mauro,Yuhei Hamaguchi,Cornelius Engelmann,Cornelius Engelmann,Cornelius Engelmann,Peng Zhang,Jae Yoon Jeong,Jeroen L.A. van Vugt,Huijuan Xiao,Huan Deng,Xu Gao,Qing Ye,Jiayuan Zhang,Longbao Yang,Ya-Qin Cai,Yi-Xin Liu,Na Liu,Zongfang Li,Tao Han,Toshimi Kaido,Joo Hyun Sohn,Christian P. Strassburg,Thomas Berg,Jonel Trebicka,Yao-Chun Hsu,Yao-Chun Hsu,Jan N. M. IJzermans,Jinhai Wang,Grace L. Su,Fanpu Ji,Mindie H. Nguyen +35 more
TL;DR: In this paper, sarcopenia was associated with an increased risk of mortality in patients with cirrhosis, by sex, underlying liver disease etiology, and severity of hepatic dysfunction.