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David M. Brazel
Researcher at University of Oxford
Publications - 24
Citations - 1699
David M. Brazel is an academic researcher from University of Oxford. The author has contributed to research in topics: Pathogen & Infertility. The author has an hindex of 12, co-authored 23 publications receiving 1137 citations. Previous affiliations of David M. Brazel include University of Colorado Boulder & Bigelow Laboratory For Ocean Sciences.
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Journal ArticleDOI
Demographic science aids in understanding the spread and fatality rates of COVID-19.
Jennifer Beam Dowd,Liliana Andriano,David M. Brazel,Valentina Rotondi,Per Block,Xuejie Ding,Yan Liu,Melinda Mills +7 more
TL;DR: The role of age structure in deaths thus far in Italy and South Korea and how the pandemic could unfold in populations with similar population sizes but different age structures are examined, showing a dramatically higher burden of mortality in countries with older versus younger populations.
Journal ArticleDOI
Capturing single cell genomes of active polysaccharide degraders: an unexpected contribution of Verrucomicrobia
Manuel Martinez-Garcia,David M. Brazel,David M. Brazel,Brandon K. Swan,Carol Arnosti,Patrick S. G. Chain,Patrick S. G. Chain,Krista G. Reitenga,Krista G. Reitenga,Gary Xie,Gary Xie,Nicole J. Poulton,Monica Lluesma Gomez,Dashiell Masland,Brian P. Thompson,Wendy K. Bellows,Kai Ziervogel,Chien Chi Lo,Chien Chi Lo,Sanaa Ahmed,Sanaa Ahmed,Cheryl D. Gleasner,Cheryl D. Gleasner,Chris Detter,Chris Detter,Ramunas Stepanauskas +25 more
TL;DR: The employed method offers a powerful tool to rapidly identify and recover discrete genomes of active players in polysaccharide degradation, without the need for cultivation, and shed light on the ecological roles of uncultured Verrucomicrobia and suggest specific taxa as promising bioprospecting targets.
Posted ContentDOI
Demographic science aids in understanding the spread and fatality rates of COVID-19
Jennifer Beam Dowd,Liliana Andriano,Valentina Rotondi,David M. Brazel,Per Block,Xuejie Ding,Yan Liu,Melinda Mills +7 more
TL;DR: The role of age structure in deaths thus far in Italy and South Korea is examined and how the pandemic could unfold in populations with similar population sizes but different age structures is illustrated, showing a dramatically higher burden of mortality in countries with older versus younger populations.
Journal ArticleDOI
Unveiling in situ interactions between marine protists and bacteria through single cell sequencing
Manuel Martinez-Garcia,David M. Brazel,David M. Brazel,Nicole J. Poulton,Brandon K. Swan,Monica Lluesma Gomez,Dashiell Masland,Michael E. Sieracki,Ramunas Stepanauskas +8 more
TL;DR: The power of single cell sequencing to untangle ecological interactions between uncultured protists and prokaryotes is demonstrated and suggests a discovery of novel symbionts associated with Cercozoa and Chrysophyta cells.
Journal ArticleDOI
Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci.
A. Mesut Erzurumluoglu,Mengzhen Liu,Victoria E. Jackson,Victoria E. Jackson,Victoria E. Jackson,Daniel R. Barnes,Gargi Datta,Gargi Datta,Carl A. Melbourne,Robin Young,Chiara Batini,Praveen Surendran,Tao Jiang,Sheikh Daud Adnan,Saima Afaq,Arpana Agrawal,Elisabeth Altmaier,Antonis C. Antoniou,Folkert W. Asselbergs,Clemens Baumbach,Laura J. Bierut,Sarah Bertelsen,Michael Boehnke,Michiel L. Bots,David M. Brazel,John C. Chambers,Jenny Chang-Claude,Jenny Chang-Claude,Chu Chen,Chu Chen,Janie Corley,Yi-Ling Chou,Sean P. David,Rudolf A. de Boer,Christiaan de Leeuw,Joe Dennis,Anna F. Dominiczak,Alison M. Dunning,Douglas F. Easton,Charles B. Eaton,Paul Elliott,Evangelos Evangelou,Evangelos Evangelou,Jessica D. Faul,Tatiana Foroud,Alison Goate,Jian Gong,Hans J. Grabe,Jeffrey Haessler,Christopher A. Haiman,Göran Hallmans,Anke R. Hammerschlag,Sarah E. Harris,Andrew T. Hattersley,Andrew C. Heath,Chris Hsu,William G. Iacono,Stavroula Kanoni,Manav Kapoor,Jaakko Kaprio,Sharon L.R. Kardia,Fredrik Karpe,Fredrik Karpe,Jukka Kontto,Jaspal S. Kooner,Charles Kooperberg,Charles Kooperberg,Kari Kuulasmaa,Markku Laakso,Dongbing Lai,Claudia Langenberg,Nhung Le,Guillaume Lettre,Guillaume Lettre,Anu Loukola,Jian'an Luan,Pamela A. F. Madden,Massimo Mangino,Massimo Mangino,Riccardo E. Marioni,Eirini Marouli,Jonathan Marten,Nicholas G. Martin,Matt McGue,Kyriaki Michailidou,Kyriaki Michailidou,Evelin Mihailov,Alireza Moayyeri,Marie Moitry,Martina Müller-Nurasyid,Aliya Naheed,Matthias Nauck,Matt Neville,Matt Neville,Sune F. Nielsen,Kari E. North,Markus Perola,Markus Perola,Paul D.P. Pharoah,Giorgio Pistis,Tinca J. C. Polderman,Danielle Posthuma,Neil Poulter,Beenish Qaiser,Asif Rasheed,Alex P. Reiner,Alex P. Reiner,Frida Renström,Frida Renström,John P. Rice,Rebecca Rohde,Olov Rolandsson,Nilesh J. Samani,Maria Samuel,David Schlessinger,Steven Scholte,Robert A. Scott,Peter S. Sever,Peter S. Sever,Yaming Shao,Nick Shrine,Jennifer A. Smith,John M. Starr,Kathleen Stirrups,Kathleen Stirrups,Danielle Stram,Heather M. Stringham,Ioanna Tachmazidou,Jean-Claude Tardif,Jean-Claude Tardif,Deborah J. Thompson,Hilary A. Tindle,Vinicius Tragante,Stella Trompet,Valérie Turcot,Jessica Tyrrell,Ilonca Vaartjes,Andries R. van der Leij,Peter van der Meer,Tibor V. Varga,Niek Verweij,Niek Verweij,Henry Völzke,Nicholas J. Wareham,Helen R. Warren,David R. Weir,Stefan Weiss,Stefan Weiss,Leah Wetherill,Hanieh Yaghootkar,Ersin Yavas,Ersin Yavas,Yu Jiang,Fang Chen,Xiaowei Zhan,Weihua Zhang,Weihua Zhang,Wei Zhao,Kaixin Zhou,Philippe Amouyel,Stefan Blankenberg,Mark J. Caulfield,Rajiv Chowdhury,Francesco Cucca,Ian J. Deary,Panos Deloukas,Panos Deloukas,Panos Deloukas,Emanuele Di Angelantonio,Emanuele Di Angelantonio,Marco M Ferrario,Jean Ferrières,Paul W. Franks,Paul W. Franks,Timothy M. Frayling,Philippe M. Frossard,Ian P. Hall,Caroline Hayward,Jan-Håkan Jansson,J. Wouter Jukema,Frank Kee,Satu Männistö,Andres Metspalu,Patricia B. Munroe,Børge G. Nordestgaard,Colin N. A. Palmer,Veikko Salomaa,Naveed Sattar,Tim D. Spector,David P. Strachan,Pim van der Harst,Eleftheria Zeggini,Danish Saleheen,Danish Saleheen,Adam S. Butterworth,Adam S. Butterworth,Louise V. Wain,Louise V. Wain,Gonçalo R. Abecasis,John Danesh,John Danesh,John Danesh,Martin D. Tobin,Martin D. Tobin,Scott I. Vrieze,Dajiang J. Liu,Joanna M. M. Howson +206 more
TL;DR: The novel loci will facilitate understanding the genetic aetiology of smoking behaviour and may lead to the identification of potential drug targets for smoking prevention and/or cessation.