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Anke H. Maitland-van der Zee
Researcher at Utrecht University
Publications - 31
Citations - 3075
Anke H. Maitland-van der Zee is an academic researcher from Utrecht University. The author has contributed to research in topics: Odds ratio & Acenocoumarol. The author has an hindex of 16, co-authored 31 publications receiving 2670 citations. Previous affiliations of Anke H. Maitland-van der Zee include University of Pennsylvania.
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Journal ArticleDOI
A Randomized Trial of Genotype-Guided Dosing of Warfarin
Munir Pirmohamed,Girvan Burnside,Niclas Eriksson,Andrea L. Jorgensen,Cheng Hock Toh,Toby Nicholson,Patrick Kesteven,Christina Christersson,Bengt Wahlström,Christina Stafberg,J. Eunice Zhang,Julian B. S. Leathart,Hugo Kohnke,Anke H. Maitland-van der Zee,Paula R Williamson,Ann K. Daly,Peter Avery,Farhad Kamali,Mia Wadelius,Abstr Act +19 more
TL;DR: Pharmacogenetic-based dosing was associated with a higher percentage of time in the therapeutic INR range than was standard dosing during the initiation of warfarin therapy.
Journal ArticleDOI
Association between alcohol and cardiovascular disease:Mendelian randomisation analysis based on individual participant data
Michael V. Holmes,Michael V. Holmes,Caroline Dale,Luisa Zuccolo,Richard J. Silverwood,Yiran Guo,Zheng Ye,David Prieto-Merino,Abbas Dehghan,Stella Trompet,Andrew Wong,Alana Cavadino,Dagmar Drogan,Sandosh Padmanabhan,Shanshan Li,Ajay Yesupriya,Maarten Leusink,Johan Sundström,Jaroslav A. Hubacek,Hynek Pikhart,Daniel I. Swerdlow,Andrie G. Panayiotou,S. A. Borinskaya,Chris Finan,Sonia Shah,Karoline Kuchenbaecker,Tina Shah,Jorgen Engmann,Lasse Folkersen,Per Eriksson,Fulvio Ricceri,Olle Melander,Carlotta Sacerdote,Dale M Gamble,Sruti Rayaprolu,Owen A. Ross,Stela McLachlan,OV Vikhireva,Ivonne Sluijs,Robert A. Scott,Vera Adamkova,Leon Flicker,Frank M. van Bockxmeer,Christine Power,Pedro Marques-Vidal,Tom W. Meade,Michael Marmot,José M. Ferro,Sofia Paulos-Pinheiro,Steve E. Humphries,Philippa J. Talmud,Irene Mateo Leach,Niek Verweij,Allan Linneberg,Tea Skaaby,Pieter A. Doevendans,Maarten J Cramer,Pim van der Harst,Olaf H. Klungel,Nicole F. Dowling,Anna F. Dominiczak,Meena Kumari,Andrew N. Nicolaides,Cornelia Weikert,Heiner Boeing,Shah Ebrahim,Tom R. Gaunt,Jackie F. Price,Lars Lannfelt,Anne Peasey,Ruzena Kubinova,Andrzej Pajak,Sofia Malyutina,Mikhail Voevoda,Mikhail Voevoda,Abdonas Tamosiunas,Anke H. Maitland-van der Zee,Paul Norman,Graeme J. Hankey,Graeme J. Hankey,Manuela M. Bergmann,Albert Hofman,Oscar H. Franco,Jackie A. Cooper,Jutta Palmen,Wilko Spiering,Pim A. de Jong,Diana Kuh,Rebecca Hardy,André G. Uitterlinden,M. Arfan Ikram,Ian Ford,Elina Hyppönen,Elina Hyppönen,Osvaldo P. Almeida,Osvaldo P. Almeida,Nicholas J. Wareham,Kay-Tee Khaw,Anders Hamsten,Anders Hamsten,Lise Lotte N. Husemoen,Anne Tjønneland,Janne Schurmann Tolstrup,Eric B. Rimm,Eric B. Rimm,Joline W.J. Beulens,W. M. Monique Verschuren,N. Charlotte Onland-Moret,Marten H. Hofker,S. Goya Wannamethee,Peter H. Whincup,Richard W Morris,Astrid M. Vicente,Hugh Watkins,Hugh Watkins,Martin Farrall,Martin Farrall,J. Wouter Jukema,James F. Meschia,L. Adrienne Cupples,Stephen J. Sharp,Myriam Fornage,Charles Kooperberg,Andrea Z. LaCroix,James Y. Dai,Matthew B. Lanktree,David S. Siscovick,Eric Jorgenson,Bonnie Spring,Josef Coresh,Yun Li,Sarah G. Buxbaum,Pamela J. Schreiner,R. Curtis Ellison,Michael Y. Tsai,Sanjay R. Patel,Sanjay R. Patel,Susan Redline,Andrew D. Johnson,Ron C. Hoogeveen,Hakon Hakonarson,Jerome I. Rotter,Eric Boerwinkle,Paul I.W. de Bakker,Mika Kivimäki,Folkert W. Asselbergs,Folkert W. Asselbergs,Naveed Sattar,Debbie A Lawlor,John C. Whittaker,John C. Whittaker,George Davey Smith,Kenneth J. Mukamal,Bruce M. Psaty,Bruce M. Psaty,James G. Wilson,Leslie A. Lange,Ajna Hamidovic,Aroon D. Hingorani,Børge G. Nordestgaard,Børge G. Nordestgaard,Martin Bobak,David A. Leon,Claudia Langenberg,Tom Palmer,Alexander P. Reiner,Brendan J. Keating,Brendan J. Keating,Frank Dudbridge,Juan P. Casas,Juan P. Casas +170 more
TL;DR: In this article, the causal role of alcohol consumption in cardiovascular disease was investigated using a Mendelian randomisation meta-analysis of 56 epidemiological studies, including 20 259 coronary heart disease cases and 10 164 stroke events.
Journal ArticleDOI
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.
Daniel I. Swerdlow,David Preiss,Karoline Kuchenbaecker,Michael V. Holmes,Jorgen Engmann,Tina Shah,Reecha Sofat,Stefan Stender,Paul C. D. Johnson,Robert A. Scott,Maarten Leusink,Niek Verweij,Stephen J. Sharp,Yiran Guo,Claudia Giambartolomei,Christina Chung,Anne Peasey,Antoinette Amuzu,KaWah Li,Jutta Palmen,Philip N. Howard,Jackie A. Cooper,Fotios Drenos,Yun Li,Gordon D.O. Lowe,John Gallacher,Marlene C. W. Stewart,Ioanna Tzoulaki,Sarah G. Buxbaum,Daphne L. van der A,Nita G. Forouhi,N. Charlotte Onland-Moret,Yvonne T. van der Schouw,Renate B. Schnabel,Jaroslav A. Hubacek,Ruzena Kubinova,Migle Baceviciene,Abdonas Tamosiunas,Andrzej Pajak,Romanvan Topor-Madry,Urszula Stepaniak,Sofia Malyutina,Damiano Baldassarre,Bengt Sennblad,Elena Tremoli,Ulf de Faire,Fabrizio Veglia,Ian Ford,J. Wouter Jukema,Rudi G. J. Westendorp,Gert J. de Borst,Pim A. de Jong,Ale Algra,Wilko Spiering,Anke H. Maitland-van der Zee,Olaf H. Klungel,Anthonius de Boer,Pieter A. Doevendans,Charles B. Eaton,Jennifer G. Robinson,David Duggan,John Kjekshus,John R. Downs,Antonio M. Gotto,Anthony C Keech,Roberto Marchioli,Gianni Tognoni,Peter S. Sever,Neil R Poulter,David D. Waters,Terje R. Pedersen,Pierre Amarenco,Haruo Nakamura,John J.V. McMurray,James Lewsey,Daniel I. Chasman,Paul M. Ridker,Aldo P. Maggioni,Luigi Tavazzi,Kausik K. Ray,Sreenivasa Rao Kondapally Seshasai,JoAnn E. Manson,Jackie F. Price,Peter H. Whincup,Richard W Morris,Debbie A Lawlor,George Davey Smith,Yoav Ben-Shlomo,Pamela J. Schreiner,Myriam Fornage,David S. Siscovick,Mary Cushman,Meena Kumari,Nicholas J. Wareham,W M Monique Verschuren,Susan Redline,Sanjay R. Patel,John C. Whittaker,Anders Hamsten,Joseph A.C. Delaney,Caroline Dale,Tom R. Gaunt,Andrew Wong,Diana Kuh,Rebecca Hardy,Sekar Kathiresan,Berta Almoguera Castillo,Pim van der Harst,Eric J. Brunner,Anne Tybjærg-Hansen,Michael Marmot,Ronald M. Krauss,Michael Y. Tsai,Josef Coresh,Ron C. Hoogeveen,Bruce M. Psaty,Leslie A. Lange,Hakon Hakonarson,Frank Dudbridge,Steve E. Humphries,Philippa J. Talmud,Mika Kivimäki,Nicholas J. Timpson,Claudia Langenberg,Folkert W. Asselbergs,Mikhail Voevoda,Martin Bobak,Hynek Pikhart,James G. Wilson,Alexander P. Reiner,Brendan J. Keating,Aroon D. Hingorani,Naveed Sattar +132 more
TL;DR: The increased risk of type 2 diabetes noted with statins is at least partially explained by HMGCR inhibition.
Journal ArticleDOI
PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study
Amand F. Schmidt,Daniel I. Swerdlow,Daniel I. Swerdlow,Michael V. Holmes,Michael V. Holmes,Riyaz S. Patel,Riyaz S. Patel,Zammy Fairhurst-Hunter,Donald M. Lyall,Fernando Pires Hartwig,Bernardo L. Horta,Elina Hyppönen,Elina Hyppönen,Christine Power,Max Moldovan,Max Moldovan,Erik P A Van Iperen,G. Kees Hovingh,Ilja Demuth,Kristina Norman,Elisabeth Steinhagen-Thiessen,Juri Demuth,Lars Bertram,Lars Bertram,Tian Liu,Stefan Coassin,Johann Willeit,Stefan Kiechl,Karin Willeit,Dan Mason,John Wright,Richard W Morris,Goya Wanamethee,Peter H. Whincup,Yoav Ben-Shlomo,Stela McLachlan,Jackie F. Price,Mika Kivimäki,Catherine Welch,Adelaida Sanchez-Galvez,Pedro Marques-Vidal,Andrew N. Nicolaides,Andrew N. Nicolaides,Andrie G. Panayiotou,N. Charlotte Onland-Moret,Yvonne T. van der Schouw,Giuseppe Matullo,Giovanni Fiorito,Simonetta Guarrera,Carlotta Sacerdote,Nicholas J. Wareham,Claudia Langenberg,Robert A. Scott,Jian'an Luan,Martin Bobak,Sofia Malyutina,Andrzej Pająk,Ruzena Kubinova,Abdonas Tamosiunas,Hynek Pikhart,Lise Lotte N. Husemoen,Niels Grarup,Oluf Pedersen,Torben Hansen,Allan Linneberg,Kenneth Starup Simonsen,Jackie A. Cooper,Steve E. Humphries,Murray H. Brilliant,Terrie Kitchner,Hakon Hakonarson,David Carrell,Catherine A. McCarty,H. Lester Kirchner,Eric B. Larson,David R. Crosslin,Mariza de Andrade,Dan M. Roden,Joshua C. Denny,Cara L. Carty,Stephen Hancock,John Attia,Elizabeth G. Holliday,Martin O'Donnell,Salim Yusuf,Michael Chong,Guillaume Paré,Pim van der Harst,M. Abdullah Said,Ruben N. Eppinga,Niek Verweij,Harold Snieder,Tim Christen,Dennis O. Mook-Kanamori,Stefan Gustafsson,Lars Lind,Erik Ingelsson,Erik Ingelsson,Erik Ingelsson,Raha Pazoki,Oscar H. Franco,Albert Hofman,André G. Uitterlinden,Abbas Dehghan,Abbas Dehghan,Alexander Teumer,Sebastian E. Baumeister,Sebastian E. Baumeister,Marcus Dörr,Markus M. Lerch,Uwe Völker,Henry Völzke,Joey Ward,Jill P. Pell,Daniel J. Smith,Tom W. Meade,Anke H. Maitland-van der Zee,Ekaterina V Baranova,Robin Young,Ian Ford,Archie Campbell,Sandosh Padmanabhan,Michiel L. Bots,Diederick E. Grobbee,Philippe Froguel,Philippe Froguel,Dorothée Thuillier,Beverley Balkau,Amélie Bonnefond,Amélie Bonnefond,Bertrand Cariou,Melissa C. Smart,Yanchun Bao,Meena Kumari,Anubha Mahajan,Paul M. Ridker,Daniel I. Chasman,Alexander P. Reiner,Leslie A. Lange,Marylyn D. Ritchie,Marylyn D. Ritchie,Folkert W. Asselbergs,Juan-Pablo Casas,Brendan J. Keating,David Preiss,David Preiss,Aroon D. Hingorani,Naveed Sattar +147 more
TL;DR: PCSK9 variants associated with lower LDL cholesterol were also associated with circulating higher fasting glucose concentration, bodyweight, and waist-to-hip ratio, and an increased risk of type 2 diabetes.
Journal ArticleDOI
A randomized trial of genotype-guided dosing of acenocoumarol and phenprocoumon
Talitha I. Verhoef,Georgia Ragia,Anthonius de Boer,Rita Barallon,Genovefa Kolovou,Vana Kolovou,Stavros Konstantinides,Saskia le Cessie,Efstratios Maltezos,Felix J. M. van der Meer,William K. Redekop,Mary Remkes,Frits R. Rosendaal,Rianne M F van Schie,Anna Tavridou,Dimitrios Tziakas,Mia Wadelius,Vangelis G. Manolopoulos,Anke H. Maitland-van der Zee +18 more
TL;DR: Genotype-guided dosing of acenocoumarol or phenprocoumon did not improve the percentage of time in the therapeutic INR range during the 12 weeks after the initiation of therapy.