D
Domenico Cozzetto
Researcher at University College London
Publications - 61
Citations - 5052
Domenico Cozzetto is an academic researcher from University College London. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 24, co-authored 37 publications receiving 4233 citations. Previous affiliations of Domenico Cozzetto include Francis Crick Institute & Guy's and St Thomas' NHS Foundation Trust.
Papers
More filters
Journal ArticleDOI
A large-scale evaluation of computational protein function prediction
Predrag Radivojac,Wyatt T. Clark,Tal Ronnen Oron,Alexandra M. Schnoes,Tobias Wittkop,Artem Sokolov,Artem Sokolov,Kiley Graim,Christopher S. Funk,Karin Verspoor,Asa Ben-Hur,Gaurav Pandey,Gaurav Pandey,Jeffrey M. Yunes,Ameet Talwalkar,Susanna Repo,Susanna Repo,Michael L Souza,Damiano Piovesan,Rita Casadio,Zheng Wang,Jianlin Cheng,Hai Fang,Julian Gough,Patrik Koskinen,Petri Törönen,Jussi Nokso-Koivisto,Liisa Holm,Domenico Cozzetto,Daniel W. A. Buchan,Kevin Bryson,David T. Jones,Bhakti Limaye,Harshal Inamdar,Avik Datta,Sunitha K Manjari,Rajendra Joshi,Meghana Chitale,Daisuke Kihara,Andreas Martin Lisewski,Serkan Erdin,Eric Venner,Olivier Lichtarge,Robert Rentzsch,Haixuan Yang,Alfonso E. Romero,Prajwal Bhat,Alberto Paccanaro,Tobias Hamp,Rebecca Kaßner,Stefan Seemayer,Esmeralda Vicedo,Christian Schaefer,Dominik Achten,Florian Auer,Ariane Boehm,Tatjana Braun,Maximilian Hecht,Mark Heron,Peter Hönigschmid,Thomas A. Hopf,Stefanie Kaufmann,Michael Kiening,Denis Krompass,Cedric Landerer,Yannick Mahlich,Manfred Roos,Jari Björne,Tapio Salakoski,Andrew Wong,Hagit Shatkay,Hagit Shatkay,Fanny Gatzmann,Ingolf Sommer,Mark N. Wass,Michael J.E. Sternberg,Nives Škunca,Fran Supek,Matko Bošnjak,Panče Panov,Sašo Džeroski,Tomislav Šmuc,Yiannis A. I. Kourmpetis,Yiannis A. I. Kourmpetis,Aalt D. J. van Dijk,Cajo J. F. ter Braak,Yuanpeng Zhou,Qingtian Gong,Xinran Dong,Weidong Tian,Marco Falda,Paolo Fontana,Enrico Lavezzo,Barbara Di Camillo,Stefano Toppo,Liang Lan,Nemanja Djuric,Yuhong Guo,Slobodan Vucetic,Amos Marc Bairoch,Amos Marc Bairoch,Michal Linial,Patricia C. Babbitt,Steven E. Brenner,Christine A. Orengo,Burkhard Rost,Sean D. Mooney,Iddo Friedberg +107 more
TL;DR: Today's best protein function prediction algorithms substantially outperform widely used first-generation methods, with large gains on all types of targets, and there is considerable need for improvement of currently available tools.
Journal ArticleDOI
PSICOV: precise structural contact prediction using sparse inverse covariance estimation on large multiple sequence alignments.
TL;DR: A novel method, PSICOV, is presented, which introduces the use of sparse inverse covariance estimation to the problem of protein contact prediction and displays a mean precision substantially better than the best performing normalized mutual information approach and Bayesian networks.
Journal ArticleDOI
DISOPRED3: precise disordered region predictions with annotated protein-binding activity
David T. Jones,Domenico Cozzetto +1 more
TL;DR: This work describes DISOPRED3, which extends its predecessor with new modules to predict IDRs and protein-binding sites within them and shows that this predictor generates precise assignments of disordered protein binding regions and that it compares well with other publicly available tools.
Journal ArticleDOI
An expanded evaluation of protein function prediction methods shows an improvement in accuracy
Yuxiang Jiang,Tal Ronnen Oron,Wyatt T. Clark,Asma R. Bankapur,Daniel D'Andrea,Rosalba Lepore,Christopher S. Funk,Indika Kahanda,Karin Verspoor,Asa Ben-Hur,Da Chen Emily Koo,Duncan Penfold-Brown,Dennis Shasha,Noah Youngs,Richard Bonneau,Alexandra Lin,Sayed Mohammad Ebrahim Sahraeian,Pier Luigi Martelli,Giuseppe Profiti,Rita Casadio,Renzhi Cao,Zhaolong Zhong,Jianlin Cheng,Adrian M. Altenhoff,Adrian M. Altenhoff,Nives Škunca,Nives Škunca,Christophe Dessimoz,Christophe Dessimoz,Christophe Dessimoz,Tunca Doğan,Kai Hakala,Suwisa Kaewphan,Farrokh Mehryary,Tapio Salakoski,Filip Ginter,Hai Fang,Ben Smithers,Matt E. Oates,Julian Gough,Petri Törönen,Patrik Koskinen,Liisa Holm,Ching-Tai Chen,Wen-Lian Hsu,Kevin Bryson,Domenico Cozzetto,Federico Minneci,David T. Jones,Samuel Chapman,Dukka Bkc,Ishita K. Khan,Daisuke Kihara,Dan Ofer,Nadav Rappoport,Amos Stern,Elena Cibrian-Uhalte,Paul Denny,Rebecca E. Foulger,Reija Hieta,Duncan Legge,Ruth C. Lovering,Michele Magrane,Anna N. Melidoni,Prudence Mutowo-Meullenet,Klemens Pichler,Aleksandra Shypitsyna,Biao Li,Pooya Zakeri,Pooya Zakeri,Sarah ElShal,Sarah ElShal,Léon-Charles Tranchevent,Léon-Charles Tranchevent,Sayoni Das,Natalie L. Dawson,David A. Lee,Jonathan G. Lees,Ian Sillitoe,Prajwal Bhat,Tamás Nepusz,Alfonso E. Romero,Rajkumar Sasidharan,Haixuan Yang,Alberto Paccanaro,Jesse Gillis,Adriana E. Sedeno-Cortes,Paul Pavlidis,Shou Feng,Juan Miguel Cejuela,Tatyana Goldberg,Tobias Hamp,Lothar Richter,Asaf Salamov,Toni Gabaldón,Toni Gabaldón,Marina Marcet-Houben,Fran Supek,Fran Supek,Qingtian Gong,Wei Ning,Yuanpeng Zhou,Weidong Tian,Marco Falda,Paolo Fontana,Enrico Lavezzo,Stefano Toppo,Carlo Ferrari,Manuel Giollo,Damiano Piovesan,Silvio C. E. Tosatto,Angela del Pozo,José M. Fernández,Paolo Maietta,Alfonso Valencia,Michael L. Tress,Alfredo Benso,Stefano Di Carlo,Gianfranco Politano,Alessandro Savino,Hafeez Ur Rehman,Matteo Re,Marco Mesiti,Giorgio Valentini,Joachim W. Bargsten,Aalt D. J. van Dijk,Branislava Gemovic,Sanja Glisic,Vladmir Perovic,Veljko Veljkovic,Nevena Veljkovic,Danillo C Almeida-E-Silva,Ricardo Z. N. Vêncio,Malvika Sharan,Jörg Vogel,Lakesh Kansakar,Shanshan Zhang,Slobodan Vucetic,Zheng Wang,Michael J.E. Sternberg,Mark N. Wass,Rachael P. Huntley,Maria Jesus Martin,Claire O'Donovan,Peter N. Robinson,Yves Moreau,Anna Tramontano,Patricia C. Babbitt,Steven E. Brenner,Michal Linial,Christine A. Orengo,Burkhard Rost,Casey S. Greene,Sean D. Mooney,Iddo Friedberg,Iddo Friedberg,Predrag Radivojac +156 more
TL;DR: The second critical assessment of functional annotation (CAFA), a timed challenge to assess computational methods that automatically assign protein function, was conducted by as mentioned in this paper. But the results of the CAFA2 assessment are limited.
Journal ArticleDOI
The PMDB Protein Model Database.
Tiziana Castrignanò,Paolo D'Onorio De Meo,Domenico Cozzetto,Ivano Giuseppe Talamo,Anna Tramontano +4 more
TL;DR: The Protein Model Database (PMDB) is a public resource aimed at storing manually built 3D models of proteins to provide access to models published in the scientific literature, together with validating experimental data.