D
Donna K. Arnett
Researcher at University of Kentucky
Publications - 36
Citations - 1254
Donna K. Arnett is an academic researcher from University of Kentucky. The author has contributed to research in topics: DNA methylation & Epigenetics. The author has an hindex of 15, co-authored 36 publications receiving 1020 citations. Previous affiliations of Donna K. Arnett include University of Alabama at Birmingham & University of South Florida.
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Journal ArticleDOI
A DNA methylation biomarker of alcohol consumption.
Chunyu Liu,Riccardo E. Marioni,Riccardo E. Marioni,Åsa K. Hedman,Liliane Pfeiffer,P-C Tsai,Lindsay M. Reynolds,Allan C. Just,Qing Duan,Cindy G. Boer,Toshiko Tanaka,Cathy E. Elks,Stella Aslibekyan,Jennifer A. Brody,B. Kuhnel,Christian Herder,Lynn M. Almli,Degui Zhi,Youfa Wang,Tianxiao Huan,Chen Yao,Michael M. Mendelson,Roby Joehanes,Liming Liang,S-A Love,Weihua Guan,Sonia Shah,Allan F. McRae,Axel Kretschmer,Holger Prokisch,Konstantin Strauch,Annette Peters,Peter M. Visscher,Peter M. Visscher,Naomi R. Wray,Xiuqing Guo,Kerri L. Wiggins,A. Smith,Elisabeth B. Binder,Kerry J. Ressler,Marguerite R. Irvin,Devin Absher,Dena G. Hernandez,Luigi Ferrucci,Stefania Bandinelli,Kurt Lohman,Jun Ding,Letizia Trevisi,Stefan Gustafsson,Johanna K. Sandling,Lisette Stolk,André G. Uitterlinden,Idil Yet,Juan E. Castillo-Fernandez,Tim D. Spector,Joel Schwartz,Pantel S. Vokonas,Lars Lind,Yun Li,Myriam Fornage,Donna K. Arnett,Nicholas J. Wareham,Nona Sotoodehnia,Ken K. Ong,J.B. van Meurs,Karen N. Conneely,Andrea A. Baccarelli,Ian J. Deary,Jordana T. Bell,Kari E. North,Yongmei Liu,M. Waldenberger,Stephanie J. London,Erik Ingelsson,Daniel Levy +74 more
TL;DR: An epigenome-wide association study of methylation of cytosine-phosphate-guanine dinucleotide (CpG) sites in relation to alcohol intake identified a robust alcohol-related DNA methylation signature and shown the potential utility ofDNA methylation as a clinically useful diagnostic test to detect current heavy alcohol consumption.
Journal ArticleDOI
Delayed Hospital Arrival for Acute Stroke: The Minnesota Stroke Survey
Maureen A. Smith,Katherine M. Doliszny,Eyal Shahar,Paul G. McGovern,Donna K. Arnett,Russell V. Luepker +5 more
TL;DR: By using medical record review, factors that influence the time from stroke onset to patient arrival at metropolitan Minneapolis-St.
Replication of a Gene-Diet Interaction in 3 Independent Populations
Dolores Corella,Gina M. Peloso,Donna K. Arnett,Serkalem Demissie,L. Adrienne Cupples,Katherine L. Tucker,Chao-Qiang Lai,Laurence D. Parnell,Oscar Coltell,Yu-Chi Lee,Jose M. Ordovas +10 more
TL;DR: In this paper, the authors analyzed gene-diet interactions between the APOA2 �265TC polymorphism and saturated fat intake on BMI and obesity in 3462 individuals from three populations in the United States: the Framingham Offspring Study (1454 whites), the Genetics of Lipid Lowering Drugs and Diet Network Study (1078 whites), and Boston- Puerto Rican Centers on Population Health and Health Disparities Study (930 Hispanics of Caribbean origin).
Journal ArticleDOI
Pharmacogenetics of antihypertensive treatment
TL;DR: To date, more than forty studies have investigated associations between genetic polymorphisms and response to antihypertensive drugs, andRenin-angiotensin-aldosterone system genes have been the most widely studied, with the angiotsin-converting enzyme I/D variant being typed in about one-half of all hypertension pharmacogenetic studies.
Journal ArticleDOI
Sickle cell trait and the risk of ESRD in blacks
Rakhi P. Naik,Marguerite R. Irvin,Suzanne E. Judd,Orlando M. Gutiérrez,Neil A. Zakai,Vimal K. Derebail,Carmen A. Peralta,Michael R. Lewis,Degui Zhi,Donna K. Arnett,William M. McClellan,James G. Wilson,Alexander P. Reiner,Jeffrey B. Kopp,Cheryl A. Winkler,Mary Cushman +15 more
TL;DR: In this cohort, SCT strongly associated with risk of progression to ESRD in blacks, and this degree of risk was similar to that conferred by APOL1 high-risk genotypes.