Jun Ding

TL;DR: It is shown that genotype imputation of common variants using HapMap haplotypes as a reference is very accurate using either genome‐wide SNP data or smaller amounts of data typical in fine‐mapping studies, and it is illustrated how association analyses of unobserved variants will benefit from ongoing advances such as larger Hap map reference panels and whole genome shotgun sequencing technologies.

TL;DR: The results provide strong support for the association of at least seven genetic loci and psoriasis (each with combined P < 5 × 10−8) and suggest priority targets for study in other auto-immune disorders.

TL;DR: In this article, the results of a genome-wide association study (GWAS) for educational attainment were reported, showing that single-nucleotide polymorphisms associated with educational attainment disproportionately occur in genomic regions regulating gene expression in the fetal brain.

TL;DR: A map of unbalanced SVs is constructed based on whole genome DNA sequencing data from 185 human genomes, integrating evidence from complementary SV discovery approaches with extensive experimental validations, and serves as a resource for sequencing-based association studies.