C
Cindy G. Boer
Researcher at Erasmus University Rotterdam
Publications - 51
Citations - 1786
Cindy G. Boer is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Medicine & Genome-wide association study. The author has an hindex of 15, co-authored 34 publications receiving 1036 citations. Previous affiliations of Cindy G. Boer include Erasmus University Medical Center & École normale supérieure de Lyon.
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Journal ArticleDOI
A DNA methylation biomarker of alcohol consumption.
Chunyu Liu,Riccardo E. Marioni,Riccardo E. Marioni,Åsa K. Hedman,Liliane Pfeiffer,P-C Tsai,Lindsay M. Reynolds,Allan C. Just,Qing Duan,Cindy G. Boer,Toshiko Tanaka,Cathy E. Elks,Stella Aslibekyan,Jennifer A. Brody,B. Kuhnel,Christian Herder,Lynn M. Almli,Degui Zhi,Youfa Wang,Tianxiao Huan,Chen Yao,Michael M. Mendelson,Roby Joehanes,Liming Liang,S-A Love,Weihua Guan,Sonia Shah,Allan F. McRae,Axel Kretschmer,Holger Prokisch,Konstantin Strauch,Annette Peters,Peter M. Visscher,Peter M. Visscher,Naomi R. Wray,Xiuqing Guo,Kerri L. Wiggins,A. Smith,Elisabeth B. Binder,Kerry J. Ressler,Marguerite R. Irvin,Devin Absher,Dena G. Hernandez,Luigi Ferrucci,Stefania Bandinelli,Kurt Lohman,Jun Ding,Letizia Trevisi,Stefan Gustafsson,Johanna K. Sandling,Lisette Stolk,André G. Uitterlinden,Idil Yet,Juan E. Castillo-Fernandez,Tim D. Spector,Joel Schwartz,Pantel S. Vokonas,Lars Lind,Yun Li,Myriam Fornage,Donna K. Arnett,Nicholas J. Wareham,Nona Sotoodehnia,Ken K. Ong,J.B. van Meurs,Karen N. Conneely,Andrea A. Baccarelli,Ian J. Deary,Jordana T. Bell,Kari E. North,Yongmei Liu,M. Waldenberger,Stephanie J. London,Erik Ingelsson,Daniel Levy +74 more
TL;DR: An epigenome-wide association study of methylation of cytosine-phosphate-guanine dinucleotide (CpG) sites in relation to alcohol intake identified a robust alcohol-related DNA methylation signature and shown the potential utility ofDNA methylation as a clinically useful diagnostic test to detect current heavy alcohol consumption.
Journal ArticleDOI
Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects
Carolina Medina-Gomez,John P. Kemp,John P. Kemp,Katerina Trajanoska,Jian'an Luan,Alessandra Chesi,Tarunveer S. Ahluwalia,Tarunveer S. Ahluwalia,Dennis O. Mook-Kanamori,Annelies C. Ham,Fernando Pires Hartwig,Daniel S. Evans,Raimo Joro,Ivana Nedeljkovic,Hou-Feng Zheng,Hou-Feng Zheng,Hou-Feng Zheng,Kun Zhu,Kun Zhu,Mustafa Atalay,Ching-Ti Liu,Maria Nethander,Linda Broer,Gudmar Porleifsson,Benjamin H. Mullin,Benjamin H. Mullin,Samuel K. Handelman,Mike A. Nalls,Leon Eyrich Jessen,Denise H. M. Heppe,J. Brent Richards,Carol A. Wang,Bo L. Chawes,Katharina E. Schraut,Najaf Amin,Nicholas J. Wareham,David Karasik,Nathalie van der Velde,Nathalie van der Velde,M. Arfan Ikram,Babette S. Zemel,Yanhua Zhou,Christian J. Carlsson,Yongmei Liu,Fiona E. McGuigan,Cindy G. Boer,Klaus Bønnelykke,Stuart H. Ralston,John A Robbins,John P. Walsh,John P. Walsh,M. Carola Zillikens,Claudia Langenberg,Ruifang Li-Gao,Frances M K Williams,Tamara B. Harris,Kristina Åkesson,Rebecca D. Jackson,Gunnar Sigurdsson,Martin den Heijer,Martin den Heijer,Bram C. J. van der Eerden,Jeroen van de Peppel,Tim D. Spector,Craig E. Pennell,Bernardo L. Horta,Janine F. Felix,Jing Hua Zhao,Scott Wilson,Scott Wilson,Scott Wilson,Renée de Mutsert,Hans Bisgaard,Unnur Styrkarsdottir,Vincent W. V. Jaddoe,Eric S. Orwoll,Timo A. Lakka,Robert A. Scott,Struan F.A. Grant,Mattias Lorentzon,Cornelia M. van Duijn,James F. Wilson,Kari Stefansson,Bruce M. Psaty,Bruce M. Psaty,Douglas P. Kiel,Claes Ohlsson,Evangelia E. Ntzani,Andre J. van Wijnen,Vincenzo Forgetta,Mohsen Ghanbari,Mohsen Ghanbari,John G. Logan,Graham R. Williams,J. H. Duncan Bassett,Peter I. Croucher,Evangelos Evangelou,Evangelos Evangelou,André G. Uitterlinden,Cheryl L. Ackert-Bicknell,Jonathan H Tobias,David M. Evans,David M. Evans,Fernando Rivadeneira +103 more
TL;DR: TB-BMD is revealed as a relevant trait for genetic studies of osteoporosis, enabling the identification of variants and pathways influencing different bone compartments and their effect can be captured throughout the life course.
Journal ArticleDOI
Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis
Eleni Zengini,Konstantinos Hatzikotoulas,Ioanna Tachmazidou,Julia Steinberg,Julia Steinberg,Fernando Pires Hartwig,Fernando Pires Hartwig,Lorraine Southam,Lorraine Southam,Sophie Hackinger,Cindy G. Boer,Unnur Styrkarsdottir,Arthur Gilly,Daniel Suveges,Britt Kilian,Thorvaldur Ingvarsson,Thorvaldur Ingvarsson,Helgi Jonsson,George C. Babis,Andrew McCaskie,André G. Uitterlinden,Joyce B. J. van Meurs,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Kari Stefansson,Kari Stefansson,George Davey Smith,George Davey Smith,Jeremy Mark Wilkinson,Eleftheria Zeggini +29 more
TL;DR: A genome-wide association study using data from UK Biobank identifies loci for knee- and hip-specific disease and establishes causal effects on osteoarthritis for higher body mass index but not for triglyceride levels or genetic predisposition to type 2 diabetes.
Journal ArticleDOI
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations
Cindy G. Boer,Konstantinos Hatzikotoulas,Lorraine Southam,Lilja Stefansdottir,Yanfei Zhang,Rodrigo Coutinho de Almeida,Tian T Wu,Jie Zheng,April Hartley,Maris Teder-Laving,Anne Heidi Skogholt,Chikashi Terao,Eleni Zengini,George Alexiadis,Andrei Barysenka,Gyda Bjornsdottir,Maiken Elvestad Gabrielsen,Arthur Gilly,Thorvaldur Ingvarsson,Marianne B Johnsen,Helgi Jonsson,Margreet Kloppenburg,Almut Luetge,Sigrun H. Lund,Reedik Mägi,Massimo Mangino,Rob G H H Nelissen,Manu Shivakumar,Julia Steinberg,Hiroshi Takuwa,Laurent F. Thomas,Margo Tuerlings,Hunt All-In Pain,George C. Babis,Jason Pui Yin Cheung,Jae Hee Kang,Peter Kraft,Steven A Lietman,Dino Samartzis,P. Eline Slagboom,Kari Stefansson,Unnur Thorsteinsdottir,Jonathan H Tobias,André G. Uitterlinden,Bendik S. Winsvold,John-Anker Zwart,George Davey Smith,Pak C. Sham,Gudmar Thorleifsson,Tom R. Gaunt,Andrew P. Morris,Ana M. Valdes,Aspasia Tsezou,Kathryn S.E. Cheah,Shiro Ikegawa,Kristian Hveem,Tõnu Esko,J. Mark Wilkinson,Ingrid Meulenbelt,Ming Ta Michael Lee,Joyce B. J. van Meurs,Unnur Styrkarsdottir,Eleftheria Zeggini +62 more
TL;DR: A genome-wide association study meta-analysis across 826,690 individuals and identifies 100 independently associated risk variants across 11 osteoarthritis phenotypes, 52 of which have not been associated with the disease before.
Journal ArticleDOI
Intestinal microbiome composition and its relation to joint pain and inflammation
Cindy G. Boer,Djawad Radjabzadeh,Carolina Medina-Gomez,Sanzhima Garmaeva,Dieuwke Schiphof,Pascal P. Arp,Thomas Koet,Alexander Kurilshikov,Jingyuan Fu,M. Arfan Ikram,Sita M A Bierma-Zeinstra,André G. Uitterlinden,Robert Kraaij,Alexandra Zhernakova,Joyce B. J. van Meurs +14 more
TL;DR: The authors analyze microbiomes from a large population based cohort and show positive correlations between abundance of Streptococcus spp.