D
Douglas C. Wallace
Researcher at Children's Hospital of Philadelphia
Publications - 495
Citations - 77420
Douglas C. Wallace is an academic researcher from Children's Hospital of Philadelphia. The author has contributed to research in topics: Mitochondrial DNA & Mitochondrion. The author has an hindex of 134, co-authored 475 publications receiving 72035 citations. Previous affiliations of Douglas C. Wallace include University of California & Stanford University.
Papers
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Patent
Inherited mitochondrial dna mutations in cancer
John A. Petros,Amanda K. Baumann,Douglas C. Wallace,Carrie Q. Sun,Muta M. Issa,Fray F. Marshall +5 more
TL;DR: In this article, a method for identifying a subject likely to have, or at risk of developing a disease condition correlated with increased reactive oxygen species (ROS), including cancer, by identifying in the subject a missense mutation in a nucleic acid of Complex III, IV and/or V of the OXPHOS system was provided.
Book ChapterDOI
Clinical Spectrum of VCP Myopathy, Paget Disease, and fronTotemporal Dementia: Experimental Models and Potential Treatments
Virginia Kimonis,Eric Dec,Mallikarjun Badadani,Angèle Nalbandian,Jouni Vesa,Vincent J. Caiozzo,Douglas C. Wallace,Barbara Martin,Charles D. Smith,Giles D. J. Watts +9 more
Journal ArticleDOI
Mitochondrial Redox Signaling in Aging-Related Diseases--In Honor of Dr. Bruce N. Ames: A Pioneer in Mitochondrial Redox Signaling on Aging Research.
Jiankang Liu,Douglas C. Wallace +1 more
Patent
Souris proteiniquement carencee en adenine de translocation nucleotidique myocardiale
TL;DR: In this article, a transgenique modifiee pour etre proteiniquement carencee en isoforme de l'adenine de translocation nucleotidique myocardiale (Ant1) is presented.
Why Do We Still Have a Maternally Inherited
TL;DR: Human mtDNA analysis has revealed these genes frequently contain region-specific adaptive polymorphisms, and the mtDNA with its energy controlling genes may have been retained to permit rapid adaptation to new environments.