Douglas Tjandra

TL;DR: Management guidelines for Lynch syndrome may require revision in light of these different gene and gender-specific risks and the good prognosis for the most commonly associated cancers.

TL;DR: The CRC stage and interval since last colonoscopy were not correlated, which is in conflict with the accelerated adenoma-carcinoma paradigm, and raises the possibility that some CRCs in path_MMR carriers may spontaneously disappear.

TL;DR: In path_MLH1 and path_MSH2 carriers, more advanced colon cancer stage was associated with poorer survival, whereas time since previous colonoscopy was not, and these results may be in conflict with the view that follow-up of path_MMR variant carriers with Colonoscopy intervals of less than 3 years provides significant benefit.

TL;DR: Findings may aid decision making for women with LS who are considering RRS and little benefit is gained by performing RRS before 40 years of age and premenopausal BSO in path_MSH6 and path_PMS2 heterozygotes has no measurable benefit for mortality.

TL;DR: Cold snare polypectomy is safe and efficacious for removing polyps <10 mm with reduced rates of delayed postpolypectomy bleeding and postpolypectsomy syndrome; however, further evidence is required to establish its safety.