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Ingrid Winship
Researcher at Royal Melbourne Hospital
Publications - 320
Citations - 11139
Ingrid Winship is an academic researcher from Royal Melbourne Hospital. The author has contributed to research in topics: Cancer & Lynch syndrome. The author has an hindex of 46, co-authored 281 publications receiving 9237 citations. Previous affiliations of Ingrid Winship include National Institutes of Health & Royal Children's Hospital.
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Clinical and molecular genetic features of pulmonary hypertension in patients with hereditary hemorrhagic telangiectasia
Richard C. Trembath,Jennifer R. Thomson,Rajiv D. Machado,Neil V. Morgan,Carl Atkinson,Ingrid Winship,G. Simonneau,Nazzareno Galiè,James E. Loyd,Marc Humbert,William C. Nichols,Nicholas W. Morrell,Jonathan Berg,Alessandra Manes,Julie McGaughran,Michael W. Pauciulo,Lisa Wheeler +16 more
TL;DR: Pulmonary hypertension in association with hereditary hemorrhagic telangiectasia can involve mutations in ALK1, a member of the transforming growth factor beta (TGF-beta) superfamily of receptors, which is associated with diverse effects, including the vascular dilatation characteristic of hereditary hemorrhage.
Journal ArticleDOI
International Nosology of Heritable Disorders of Connective Tissue, Berlin, 1986.
Peter Beighton,A. De Paepe,David M. Danks,G. Finidori,T. Gedde-Dahl,R. M. Goodman,Judith G. Hall,David W. Hollister,William A. Horton,Victor A. McKusick,John M. Opitz,F. M. Pope,Reed E. Pyeritz,David L. Rimoin,David Sillence,J. Spranger,Elizabeth Thompson,Petros Tsipouras,Denis Viljoen,Ingrid Winship,I. D. Young,James F. Reynolds +21 more
TL;DR: A group of experts participated in a Workshop held during the 7th International Congress of Human Genetics, Berlin, in September, 1986 as discussed by the authors, where overviews were given of the uses and limitations of nosology, diagnostic criteria (Pyeritz), and practical issues in biochemical and molecular diagnosis.
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A Prospective Study of Sudden Cardiac Death among Children and Young Adults
Richard D. Bagnall,Robert G. Weintraub,Jodie Ingles,Jodie Ingles,Johan Duflou,Johan Duflou,Laura Yeates,Laura Yeates,Lien Lam,Andrew M. Davis,T. Thompson,V. Connell,Jennie Wallace,Charles Naylor,Jackie Crawford,Donald R. Love,Lavinia Hallam,Jodi White,Christopher Lawrence,Matthew J Lynch,Natalie Morgan,Paul A. James,Desirée du Sart,Rajesh Puranik,Rajesh Puranik,Neil E. I. Langlois,Jitendra K. Vohra,Ingrid Winship,John Atherton,Julie McGaughran,Jonathan R. Skinner,Christopher Semsarian,Christopher Semsarian +32 more
TL;DR: The addition of genetic testing to autopsy investigation substantially increased the identification of a possible cause of sudden cardiac death among children and young adults.
Journal ArticleDOI
The clinical phenotype of Lynch syndrome due to germ-line PMS2 mutations
Leigha Senter,Mark Clendenning,Kaisa Sotamaa,Heather Hampel,Jane Green,John D. Potter,Annika Lindblom,Kristina Lagerstedt,Stephen N. Thibodeau,Noralane M. Lindor,Joanne P. Young,Ingrid Winship,James G. Dowty,Darren M. White,John L. Hopper,Laura Baglietto,Mark A. Jenkins,Albert de la Chapelle +17 more
TL;DR: PMS2 mutations contribute significantly to Lynch syndrome, but the penetrance for monoallelic mutation carriers appears to be lower than that for the other mismatch repair genes.
Journal ArticleDOI
Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
Mev Dominguez-Valentin,Julian R. Sampson,Toni T. Seppälä,Sanne W. ten Broeke,John-Paul Plazzer,Sigve Nakken,Christoph Engel,Stefan Aretz,Mark A. Jenkins,Lone Sunde,Lone Sunde,Inge Bernstein,Gabriel Capellá,Francesc Balaguer,Huw D. Thomas,D. Gareth Evans,D. Gareth Evans,John Burn,Marc S. Greenblatt,Eivind Hovig,Wouter H. de Vos tot Nederveen Cappel,Rolf H. Sijmons,Lucio Bertario,Maria Grazia Tibiletti,Giulia Martina Cavestro,Annika Lindblom,Adriana Della Valle,Francisco López-Köstner,Nathan Gluck,Lior H. Katz,Karl Heinimann,Carlos A. Vaccaro,Reinhard Büttner,Heike Görgens,Elke Holinski-Feder,Monika Morak,Stefanie Holzapfel,Robert Hüneburg,Magnus von Knebel Doeberitz,Magnus von Knebel Doeberitz,Markus Loeffler,Nils Rahner,Hans K. Schackert,Verena Steinke-Lange,Wolff Schmiegel,Deepak Vangala,Kirsi Pylvänäinen,Laura Renkonen-Sinisalo,Laura Renkonen-Sinisalo,John L. Hopper,Aung Ko Win,Robert W. Haile,Noralane M. Lindor,Steven Gallinger,Loic Le Marchand,Polly A. Newcomb,Jane C. Figueiredo,Stephen N. Thibodeau,Karin Wadt,Christina Therkildsen,Henrik Okkels,Zohreh Ketabi,Leticia Moreira,Ariadna Sánchez,Miquel Serra-Burriel,Marta Pineda,Matilde Navarro,Ignacio Blanco,Kate Green,Fiona Lalloo,Emma J Crosbie,James Hill,Oliver G. Denton,Ian M. Frayling,Einar Andreas Rødland,Hans F. A. Vasen,Miriam Mints,Florencia Neffa,Patricia Esperon,Karin Alvarez,Revital Kariv,Guy Rosner,Tamara Alejandra Piñero,María Laura Gonzalez,Pablo Kalfayan,Douglas Tjandra,Ingrid Winship,Ingrid Winship,Finlay A. Macrae,Finlay A. Macrae,Gabriela Möslein,Jukka-Pekka Mecklin,Maartje Nielsen,Pål Møller,Pål Møller +94 more
TL;DR: Management guidelines for Lynch syndrome may require revision in light of these different gene and gender-specific risks and the good prognosis for the most commonly associated cancers.