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Erwin W. Gelfand
Researcher at University of Colorado Denver
Publications - 679
Citations - 37565
Erwin W. Gelfand is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Immunoglobulin E & T cell. The author has an hindex of 99, co-authored 675 publications receiving 36059 citations. Previous affiliations of Erwin W. Gelfand include University of Colorado Hospital & University of Virginia.
Papers
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Journal ArticleDOI
Spectrum of T-lymphocyte activities regulating allergic lung inflammation.
TL;DR: Only by carefully defining mechanistic pathways, delineating their sensitivity to corticosteroids, and determining the balance between regulatory and effector pathways will precision medicine become a reality with selective and effective application of targeted therapies.
Journal Article
Serum levels of surfactant protein D are increased in mice with lung tumors.
Feijie Zhang,William Pao,Sarah M. Umphress,Sonia B. Jakowlew,Amy M. Meyer,Lori D. Dwyer-Nield,Larry D. Nielsen,Katsuyuki Takeda,Erwin W. Gelfand,James H. Fisher,Lening Zhang,Alvin M. Malkinson,Robert J. Mason +12 more
TL;DR: In this paper, the authors found that serum surfactant protein (SP)-D was increased in mice bearing lung tumors and that the SP-D level correlated with tumor volume.
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Fas deficiency delays the resolution of airway hyperresponsiveness after allergen sensitization and challenge
TL;DR: The results suggest that Fas expression can regulate the onset and resolution of AHR through an increase in eosinophil apoptosis.
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The Critical Role of Complement Alternative Pathway Regulator Factor H in Allergen-Induced Airway Hyperresponsiveness and Inflammation
Katsuyuki Takeda,Joshua M. Thurman,Stephen Tomlinson,Masakazu Okamoto,Yoshiki Shiraishi,Viviana P. Ferreira,Claudio Cortes,Michael K. Pangburn,V. Michael Holers,Erwin W. Gelfand +9 more
TL;DR: Although endogenous factor H does play a role in limiting the development of AHR, strategies to deliver the complement-regulatory region of factor H specifically to the site of inflammation provide greater protection than that afforded by endogenous regulators.
Journal ArticleDOI
Abnormal Lymphocyte Capping in a Patient with Severe Combined Immunodeficiency Disease
TL;DR: The theory that plasma-membrane-cytoskeleton interactions have a role in the expression of specific immunity is supported and new areas that should be considered in trying to understand the primary immunodeficiency diseases are identified.