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Erwin W. Gelfand
Researcher at University of Colorado Denver
Publications - 679
Citations - 37565
Erwin W. Gelfand is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Immunoglobulin E & T cell. The author has an hindex of 99, co-authored 675 publications receiving 36059 citations. Previous affiliations of Erwin W. Gelfand include University of Colorado Hospital & University of Virginia.
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Journal ArticleDOI
Negative regulation of airway responsiveness that is dependent on gammadelta T cells and independent of alphabeta T cells.
Michael Lahn,Arihiko Kanehiro,Katsuyuki Takeda,Anthony Joetham,Jürgen Schwarze,Gabriele Köhler,Rebecca L. O'Brien,Erwin W. Gelfand,Willi K. Born +8 more
TL;DR: It is demonstrated that γδ T cells can regulate airway function in an αβ T cell-independent manner, identifying them as important cells in pulmonary homeostasis.
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Effector CD8^+ T cells mediate inflammation and airway hyper-responsiveness
Nobuaki Miyahara,Bradley J. Swanson,Katsuyuki Takeda,Christian Taube,Satoko Miyahara,Taku Kodama,Azzeddine Dakhama,Vanessa L. Ott,Erwin W. Gelfand +8 more
TL;DR: Data suggest an important role for effector CD8+ T cells in the development of AHR and airway inflammation, which may be associated with their Tc2-type cytokine production and their capacity to migrate into the lung.
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In vitro and in vivo effects of deferoxamine in neonatal acute leukemia
Zeev Estrov,Akio Tawa,Xin-Hua Wang,Ian D. Dubé,Hassan Sulh,Amos Cohen,Erwin W. Gelfand,Melvin H. Freedman +7 more
TL;DR: The findings indicate that DFO has antileukemic properties by virtue of its effects on proliferation and differentiation, and they prompt further experimental and clinical studies with this agent.
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Selective activation of c-Jun kinase mitogen-activated protein kinase by CD40 on human B cells.
Naoki Sakata,Hiren R. Patel,Naohiro Terada,Alejandro Aruffo,Gary L. Johnson,Erwin W. Gelfand +5 more
TL;DR: Results suggest that independent, parallel protein kinase response pathways are involved in the integration of sIgM and CD40 control of B cell phenotype and function.
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Temporal association between airway hyperresponsiveness and airway eosinophilia in ovalbumin-sensitized mice.
Adrian Tomkinson,G Cieslewicz,Catherine Duez,Kirsten A. Larson,James J. Lee,Erwin W. Gelfand +5 more
TL;DR: A temporal association between Th2 cytokine production, tissue eosinophil infiltration and activation, and, importantly, both the development and resolution kinetics of AHR is identified.