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Erwin W. Gelfand
Researcher at University of Colorado Denver
Publications - 679
Citations - 37565
Erwin W. Gelfand is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Immunoglobulin E & T cell. The author has an hindex of 99, co-authored 675 publications receiving 36059 citations. Previous affiliations of Erwin W. Gelfand include University of Colorado Hospital & University of Virginia.
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Journal ArticleDOI
Inhibition of Spleen Tyrosine Kinase Prevents Mast Cell Activation and Airway Hyperresponsiveness
Shigeki Matsubara,Guiming Li,Katsuyuki Takeda,Joan E. Loader,Polly Pine,Esteban Masuda,Nobuaki Miyahara,Satoko Miyahara,Joseph J. Lucas,Azzeddine Dakhama,Erwin W. Gelfand +10 more
TL;DR: A functional role for Syk is delineated in the development of mast cell- and IgE-mediated AHR and airway inflammation, and these results indicate that inhibition of Syk may be a target in the treatment of allergic asthma.
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Distribution and leukocyte contacts of γδ T cells in the lung
J. M. Wands,Christina L. Roark,M. Kemal Aydintug,Niyun Jin,Youn Soo Hahn,Laura Cook,Xiang Yin,Joseph Dal Porto,Michael Lahn,Dallas M. Hyde,Erwin W. Gelfand,Robert J. Mason,Rebecca L. O'Brien,Willi K. Born +13 more
TL;DR: It is shown that γδ and αβ T cells are distributed differently in the normal mouse lung, and the �γδ T cells have a bias for nonalveolar locations, with the exception of the airway mucosa.
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Do NHLBI lung function criteria apply to children? A cross‐sectional evaluation of childhood asthma at National Jewish Medical and Research Center, 1999–2002
TL;DR: The majority of asthmatic children attending a tertiary care facility had FEV1 values within normal range, suggesting impaired airway but not lung growth in children with asthma.
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Selective toxicity of purine deoxynucleosides for human lymphocyte growth and function
TL;DR: Some initial understanding is provided for the selective loss of specific lymphocyte functions in individuals with inborn errors of purine metabolism in the context of inherited deficiencies of these enzymes.
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Demonstration of an intrathymic defect in a case of severe combined immunodeficiency disease.
TL;DR: The experimental results suggest that in this case, lymphoid precursor cells were present in the bone marrow but failed to differentiate to functional maturity due to a defect in maturation of thymic tissue.