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Erwin W. Gelfand
Researcher at University of Colorado Denver
Publications - 679
Citations - 37565
Erwin W. Gelfand is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Immunoglobulin E & T cell. The author has an hindex of 99, co-authored 675 publications receiving 36059 citations. Previous affiliations of Erwin W. Gelfand include University of Colorado Hospital & University of Virginia.
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Journal Article
Inactivation of NF-κB by EBV BZLF-1-Encoded ZEBRA Protein in Human T Cells
TL;DR: Observations suggest that inactivation of NF-κB transcription by ZEBRA in EBV-infected T cells may be a novel mechanism of viral pathogenesis analogous in part to over-expression of the endogenous cytoplasmic inhibitor of NF -κB, IκBα.
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Reduced thymic output, cell cycle abnormalities, and increased apoptosis of T lymphocytes in patients with cartilage-hair hypoplasia
Miguel Angel de la Fuente,Mike Recher,Nicholas L. Rider,Kevin A. Strauss,Kevin A. Strauss,D. Holmes Morton,D. Holmes Morton,Margaret Adair,Francisco A. Bonilla,Hans D. Ochs,Erwin W. Gelfand,Itai M. Pessach,Jolan E. Walter,Alejandra King,Silvia Giliani,Sung-Yun Pai,Luigi D. Notarangelo +16 more
TL;DR: These data confirm that RMRP mutations result in significant defects of cell-mediated immunity and provide a link between the cellular phenotype and the immunodeficiency in CHH.
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Impact of a novel nutritional formula on asthma control and biomarkers of allergic airway inflammation in children
Ronina A. Covar,Melanie Gleason,B. Macomber,L. Stewart,P. Szefler,K. Engelhardt,James Murphy,Andrew H. Liu,S. Wood,S. DeMichele,Erwin W. Gelfand,Stanley J. Szefler +11 more
TL;DR: A novel nutritional formula enriched in eicosapentaenoic and γ‐linolenic fatty acids and antioxidants reduces airway inflammation and improves clinical outcomes in critically ill patients, but NNF has not been evaluated in chronic inflammatory diseases such as persistent asthma.
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Combined blockade of the histamine H1 and H4 receptor suppresses peanut‐induced intestinal anaphylaxis by regulating dendritic cell function
TL;DR: Signaling through histamine receptors on dendritic cells (DCs) may be involved in the effector phase of peanut‐induced intestinal anaphylaxis.
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Inhibition of Pim1 kinase prevents peanut allergy by enhancing Runx3 expression and suppressing TH2 and TH17 T-cell differentiation
Meiqin Wang,Masakazu Okamoto,Joanne Domenico,Junyan Han,Shigeru Ashino,Yoo Seob Shin,Erwin W. Gelfand +6 more
TL;DR: In sensitized and challenged Runx3(+/-) mice, inhibition of Pim1 kinase had less effect on the development of the full spectrum of intestinal allergic responses, and data support a novel regulatory axis involving Pim 1 kinase and Runx 3 in the control of food-induced allergic reactions through the regulation of T(H)2 and T( H)17 differentiation.