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Erwin W. Gelfand
Researcher at University of Colorado Denver
Publications - 679
Citations - 37565
Erwin W. Gelfand is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Immunoglobulin E & T cell. The author has an hindex of 99, co-authored 675 publications receiving 36059 citations. Previous affiliations of Erwin W. Gelfand include University of Colorado Hospital & University of Virginia.
Papers
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Journal Article
Antagonistic effects of calcium ionophores and phorbol esters on T cell receptor mRNA levels in human thymocytes.
TL;DR: The results provide the first evidence for antagonistic actions of protein kinase C and cytosolic-free Ca2+ on gene expression.
Journal ArticleDOI
Pulmonary Manifestations of Common Variable Immunodeficiency
Tami J. Bang,John Caleb Richards,Amy L. Olson,Steve D. Groshong,Erwin W. Gelfand,David A. Lynch +5 more
TL;DR: The purpose of this paper was to describe the clinical, radiologic, and pathologic findings of CVID-associated lung diseases, which include airways' disease, interstitial lung disease, lymphoma, and mucosa-associated lymphoid tissue lymphoma.
Journal ArticleDOI
Phenotypic features of selective T cell deficiency characterized by absence of CD8+ T lymphocytes and undetectable mRNA for ZAP-70 kinase.
Bruce Mazer,Ronald J. Harbeck,Ronald J. Harbeck,Richard A. Franklin,Richard A. Franklin,Reinhart Schwinzer,Reinhart Schwinzer,Ralph T. Kubo,Ralph T. Kubo,Anthony R. Hayward,Anthony R. Hayward,Erwin W. Gelfand,Erwin W. Gelfand +12 more
TL;DR: The data support the concept that the defect in signal transduction resulting from the absence of Zap-70 is primarily manifested following export of T lymphocytes from the thymus and that selection of CDS-positive T cells is dependent on the presence of ZAP-70.
Journal ArticleDOI
Immunomodulatory Effects of Ambroxol on Airway Hyperresponsiveness and Inflammation
Katsuyuki Takeda,Nobuaki Miyahara,Shigeki Matsubara,Christian Taube,Kenichi Kitamura,Astushi Hirano,Mitsune Tanimoto,Erwin W. Gelfand +7 more
TL;DR: Ambroxol was effective in preventing AHR and airway inflammation through upregulation of Th1 cytokines and protection from oxidative stress in the airways.
Book ChapterDOI
Sensitivity of T-Leukemic Cells to Deoxyguanosine and Arabinosyl Guanine
TL;DR: This work has shown that following incubation with GdR, immature T-cells fail to proliferate, rapidly accumulate deoxyGTP, and fail to eliminate the nucleotide.