Franco Berrino

TL;DR: In this paper, a two-stage genome-wide association study of pancreatic cancer, a cancer with one of the lowest survival rates worldwide, was conducted, where 558,542 SNPs were genotyped in 1,896 individuals and 1,939 controls drawn from 12 prospective cohorts plus one hospital-based case-control study.

TL;DR: An association between a locus on 9q34 and pancreatic cancer marked by the SNP rs505922 is identified, consistent with earlier epidemiologic evidence suggesting that people with blood group O may have a lower risk of pancreaticcancer than those with groups A or B.

TL;DR: In western Europe, an important proportion of cases of cancer can be attributable to alcohol consumption, especially consumption higher than the recommended upper limits, which support current political efforts to reduce or to abstain from alcohol consumption to reduce the incidence of cancer.

TL;DR: The findings indicate that specific plasma phospholipid fatty acids are suitable biomarkers of some food intakes in the EPIC Study and suggest complex interactions between alcohol intake and fatty acid metabolism, which warrants further attention in epidemiologic studies relating dietary fatty acids to alcohol-related cancers and other chronic diseases.

TL;DR: It is confirmed that hyperinsulinemia, as determined by C‐peptide levels, is associated with an increased colorectal cancer risk.