Fusano Todokoro

TL;DR: The latest version of the RAP-DB contains a variety of annotation data as follows: clone positions, structures and functions of 31 439 genes validated by cDNAs, RNA genes detected by massively parallel signature sequencing (MPSS) technology and sequence similarity, flanking sequences of mutant lines, transposable elements, etc.

TL;DR: The results suggest that natural selection may have played a role for duplicated genes in both species, so that duplication was suppressed or favored in a manner that depended on the function of a gene.

TL;DR: H-InvDB as mentioned in this paper is a comprehensive annotation resource for human genes and transcripts, including gene structures, gene functions, alternative splicing variants, functional non-protein-coding RNAs, functional domains, predicted sub cellular localizations, metabolic pathways, predictions of protein 3D structure, mapping of SNPs and microsatellite repeat motifs, co-localization with orphan diseases, gene expression profiles, orthologous genes, protein-protein interactions (PPI) and annotation for gene families.

TL;DR: The extended database and data mining resources newly released in the H-Invitational Database, including ‘Navigation search’, ‘H-InvDB Enrichment Analysis Tool (HEAT)’ and web service APIs.

TL;DR: A fully curated database of evolutionary features of human genes, called ‘Evola’, which provides amino acid sequence alignments and phylogenetic trees of orthologs and homologs, and is expected to serve as a comprehensive and reliable database to be utilized in comparative analyses for obtaining new knowledge about human genes.