G
Greg L Medlock
Researcher at University of Virginia
Publications - 4
Citations - 175
Greg L Medlock is an academic researcher from University of Virginia. The author has contributed to research in topics: Microbiome & Environmental enteropathy. The author has an hindex of 4, co-authored 4 publications receiving 135 citations.
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Journal ArticleDOI
Protein- and zinc-deficient diets modulate the murine microbiome and metabolic phenotype
Jordi Mayneris-Perxachs,David T. Bolick,Joy Leng,Greg L Medlock,Glynis L. Kolling,Jason A. Papin,Jonathan R. Swann,Richard L. Guerrant +7 more
TL;DR: The results show that the metabolic consequences of malnutrition in the mouse can be modeled to help dissect relevant pathways involved in the effects of undernutrition and their contribution to environmental enteric dysfunction.
Posted ContentDOI
Memote: A community-driven effort towards a standardized genome-scale metabolic model test suite
Christian Lieven,Moritz Emanuel Beber,Brett G. Olivier,Frank Bergmann,Meriç Ataman,Parizad Babaei,Jennifer A. Bartell,Lars M. Blank,Siddharth Chauhan,Kevin Correia,Christian Diener,Andreas Dräger,Birgitta E. Ebert,Janaka N. Edirisinghe,José P. Faria,Adam M. Feist,Georgios Fengos,Ronan M. T. Fleming,Beatriz García-Jiménez,Vassily Hatzimanikatis,Wout van Helvoirt,Christopher S. Henry,Henning Hermjakob,Markus J. Herrgård,Hyun Uk Kim,Zachary A. King,Jasper J. Koehorst,Steffen Klamt,Edda Klipp,Meiyappan Lakshmanan,Nicolas Le Novère,Dong-Yup Lee,Sang Yup Lee,Sunjae Lee,Nathan E. Lewis,Hongwu Ma,Daniel Machado,Radhakrishnan Mahadevan,Paulo Maia,Adil Mardinoglu,Greg L Medlock,Jonathan M. Monk,Jens Nielsen,Lars K. Nielsen,Juan Nogales,Intawat Nookaew,Osbaldo Resendis,Bernhard O. Palsson,Jason A. Papin,Kiran Raosaheb Patil,Nathan D. Price,Anne Richelle,Isabel Rocha,Benjamin Sanchez,Peter J. Schaap,Rahuman S. Malik Sheriff,Saeed Shoaie,Nikolaus Sonnenschein,Bas Teusink,Paulo Vilaça,Jon Olav Vik,Judith A. H. Wodke,Joana C. Xavier,Qianqian Yuan,Maksim Zakhartsev,Cheng Zhang +65 more
TL;DR: For example, Memote as mentioned in this paper is an open-source software containing a community-maintained, standardized set of metabolic model tests, which can be extended to include experimental datasets for automatic model validation.
Journal ArticleDOI
Mucosal Genomics Implicate Lymphocyte Activation and Lipid Metabolism in Refractory Environmental Enteric Dysfunction.
Yael Haberman,Yael Haberman,Najeeha Talat Iqbal,Sudhir Ghandikota,Indika Mallawaarachchi,Tzipi Braun,Phillip J. Dexheimer,Najeeb Rahman,Rotem Hadar,Kamran Sadiq,Zubair Ahmad,Romana Idress,Junaid Iqbal,Sheraz Ahmed,Aneeta Hotwani,Fayyaz Umrani,Lubaina Ehsan,Greg L Medlock,Sana Syed,Sana Syed,Chris Moskaluk,Jennie Z. Ma,Anil G. Jegga,Anil G. Jegga,Sean R. Moore,Syed Asad Ali,Lee A. Denson +26 more
TL;DR: The study of Environmental Enteropathy and Malnutrition (SEEM) followed 416 children from birth to 24 months in a rural district in Pakistan and measured at 9 months and tested for association with growth at 24 months as discussed by the authors.
Journal ArticleDOI
Increased Urinary Trimethylamine N-Oxide Following Cryptosporidium Infection and Protein Malnutrition Independent of Microbiome Effects.
David T. Bolick,Jordi Mayneris-Perxachs,Greg L Medlock,Glynis L. Kolling,Jason A. Papin,J. Swann,Richard L. Guerrant +6 more
TL;DR: It is concluded that cryptosporidial infection in protein-deficient mice can mimic some metabolic changes seen in malnourished children and may help elucidate the understanding of long-term metabolic consequences of early childhood enteric infections.