Qianqian Yuan

TL;DR: A community effort to develop a test suite named MEMOTE (for metabolic model tests) to assess GEM quality, and advocate adoption of the latest version of the Systems Biology Markup Language level 3 flux balance constraints (SBML3FBC) package as the primary description and exchange format.

TL;DR: In this paper, a chemical-biochemical hybrid pathway for starch synth synthesis was proposed, which is a major source of calories in the human diet and a primary feedstock for bio-industry.

TL;DR: For example, Memote as mentioned in this paper is an open-source software containing a community-maintained, standardized set of metabolic model tests, which can be extended to include experimental datasets for automatic model validation.

TL;DR: Memote is presented, an open-source software containing a community-maintained, standardized set of metabolic model tests that provides a measure for model quality that is consistent across reconstruction platforms and analysis software and simplifies collaboration within the community by establishing workflows for publicly hosted and version controlled models.

TL;DR: Wang et al. improve the methanol tolerance for the synthetic methylotroph, Corynebacterium glutamicum, and generate 3 new strains by directed evolution and use biochemical, transcriptomic, and genetic approaches to characterize the pathways underlying the enhanced meethanol metabolism.