Hong Dang

TL;DR: The nasal susceptibility to SARS-CoV-2 with likely subsequent aspiration-mediated virus seeding to the lung in SARS/COVID-19 pathogenesis is highlighted and reagents provide a foundation for investigations into virus-host interactions in protective immunity, host susceptibility, and virus pathogenesis.

TL;DR: This paper used genome-wide association analysis to identify genetic modifiers of CF lung disease, the primary cause of mortality, and provided new insights into potential targets for modulating lung disease severity in CF.

TL;DR: In normal/healthy human airways, MUC5B is the dominant secretory mucin in the superficial epithelium and glands, with distal airways being a major site of expression.

TL;DR: Chronic vaping exerts marked biological effects on the lung and these effects may in part be mediated by the PG/VG base, likely not harmless and may have clinical implications for the development of chronic lung disease.

TL;DR: Bronchial epithelial cells grew exponentially in feeders plus Y, dramatically surpassing the numbers of conventionally grown cells, and CRC technology expands the supply of functional primary CF HBE cells for testing CFTR modulators in Ussing chambers.