I
Irena Martinović Klarić
Publications - 39
Citations - 1960
Irena Martinović Klarić is an academic researcher. The author has contributed to research in topics: Population & Haplogroup. The author has an hindex of 20, co-authored 39 publications receiving 1806 citations.
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Journal ArticleDOI
SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout
Veronique Vitart,Igor Rudan,Igor Rudan,Caroline Hayward,Nicola K. Gray,Nicola K. Gray,James A B Floyd,Colin N. A. Palmer,Sara Knott,Ivana Kolcic,Ozren Polasek,Ozren Polasek,Juergen Graessler,James F. Wilson,Anthony M. Marinaki,Philip Riches,Xinhua Shu,Branka Janićijević,Nina Smolej-Narančić,Barbara Gorgoni,Barbara Gorgoni,Joanne E. Morgan,Susan Campbell,Zrinka Biloglav,Lovorka Barac-Lauc,Marijana Peričić,Irena Martinović Klarić,Lina Zgaga,Tatjana Škarić-Jurić,Sarah H. Wild,William A. Richardson,Peter Hohenstein,Charley H Kimber,Albert Tenesa,Louise A. Donnelly,Lynette D. Fairbanks,Martin Aringer,Paul M. McKeigue,Stuart H. Ralston,Andrew D. Morris,Pavao Rudan,Nicholas D. Hastie,Harry Campbell,Alan F. Wright +43 more
TL;DR: Genetic variants within a transporter gene, SLC2A9, that explain 1.7–5.3% of the variance in serum uric acid concentrations are identified following a genome-wide association scan in a Croatian population sample and it is shown that it has strong uric Acid transport activity in Xenopus laevis oocytes.
Journal ArticleDOI
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways
Lisette Stolk,John R. B. Perry,John R. B. Perry,Daniel I. Chasman,Chunyan He,Massimo Mangino,Patrick Sulem,Maja Barbalić,Linda Broer,Enda M. Byrne,Florian Ernst,Tmu Esko,Nora Franceschini,Daniel F. Gudbjartsson,Jouke-Jan Hottenga,Peter Kraft,Peter Kraft,Patrick F. McArdle,Eleonora Porcu,So-Youn Shin,Albert V. Smith,Sophie H. Van Wingerden,Guangju Zhai,Guangju Zhai,Wei V. Zhuang,Eva Albrecht,Behrooz Z. Alizadeh,Thor Aspelund,Stefania Bandinelli,Lovorka Barać Lauc,Jacques S. Beckmann,Mladen Boban,Eric Boerwinkle,Frank J.M. Broekmans,Andrea Burri,Harry Campbell,Stephen J. Chanock,Constance Chen,Marilyn C. Cornelis,Tanguy Corre,Andrea D. Coviello,Pio D'Adamo,Gail Davies,Ulf de Faire,Eco J. C. de Geus,Ian J. Deary,George Dedoussis,Panagiotis Deloukas,Shah Ebrahim,Gudny Eiriksdottir,Valur Emilsson,Johan G. Eriksson,Bart C.J.M. Fauser,Liana Ferreli,Luigi Ferrucci,Krista Fischer,Aaron R. Folsom,Melissa E. Garcia,Paolo Gasparini,Christian Gieger,Nicole L. Glazer,Diederick E. Grobbee,Per Hall,Toomas Haller,Susan E. Hankinson,Merli Hass,Caroline Hayward,Andrew C. Heath,Albert Hofman,Erik Ingelsson,A. Cecile J.W. Janssens,Andrew D. Johnson,David Karasik,David Karasik,Sharon L.R. Kardia,Jules J. Keyzer,Douglas P. Kiel,Douglas P. Kiel,Ivana Kolcic,Z. Kutalik,Z. Kutalik,Jari Lahti,Sandra Lai,Triin Laisk,Joop S.E. Laven,Debbie A Lawlor,Jianjun Liu,Lorna M. Lopez,Yvonne V. Louwers,Patrik K. E. Magnusson,Mara Marongiu,Nicholas G. Martin,Irena Martinović Klarić,Corrado Masciullo,Barbara McKnight,Sarah E. Medland,David Melzer,Vincent Mooser,Pau Navarro,Anne B. Newman,Dale R. Nyholt,N. Charlotte Onland-Moret,Aarno Palotie,Guillaume Paré,Guillaume Paré,Alexander N. Parker,Nancy L. Pedersen,Petra H.M. Peeters,Giorgio Pistis,Andrew S. Plump,Ozren Polasek,Victor J M Pop,Bruce M. Psaty,Bruce M. Psaty,Katri R Currency Signikkönen,Emil Rehnberg,Jerome I. Rotter,Igor Rudan,Igor Rudan,Cinzia Sala,Andres Salumets,Angelo Scuteri,Andrew B. Singleton,Jennifer A. Smith,Harold Snieder,Nicole Soranzo,Nicole Soranzo,Simon N. Stacey,John M. Starr,Maria G. Stathopoulou,Kathleen Stirrups,Ronald P. Stolk,Unnur Styrkarsdottir,Yan V. Sun,Albert Tenesa,Barbara Thorand,Daniela Toniolo,Laufey Tryggvadottir,Kim Tsui,Sheila Ulivi,Rob M. van Dam,Rob M. van Dam,Yvonne T. van der Schouw,Carla H. van Gils,Peter Van Nierop,Jacqueline M. Vink,Peter M. Visscher,Peter M. Visscher,Marlies Voorhuis,Gérard Waeber,Henri Wallaschofski,H.-Erich Wichmann,Elisabeth Widen,Colette J M Wijnands-van Gent,Gonneke Willemsen,James F. Wilson,Bruce H. R. Wolffenbuttel,Alan F. Wright,Laura M. Yerges-Armstrong,Tatijana Zemunik,Lina Zgaga,Lina Zgaga,M. Carola Zillikens,Marek Zygmunt,Alice M. Arnold,Dorret I. Boomsma,Julie E. Buring,Laura Crisponi,Ellen W. Demerath,Ellen W. Demerath,Vilmundur Gudnason,Tamara B. Harris,Frank B. Hu,David J. Hunter,David J. Hunter,Lenore J. Launer,Andres Metspalu,Grant W. Montgomery,Ben A. Oostra,Paul M. Ridker,Serena Sanna,David Schlessinger,Tim D. Spector,Kari Stefansson,Kari Stefansson,Elizabeth A. Streeten,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Manuela Uda,André G. Uitterlinden,Cornelia M. van Duijn,Henry Völzke,Anna Murray,Anna Murray,Joanne M. Murabito,Jenny A. Visser,Jenny A. Visser,Kathryn L. Lunetta,Kathryn L. Lunetta +198 more
TL;DR: A meta-analysis of 22 genome-wide association studies in 38,968 women of European descent identified 13 loci newly associated with age at natural menopause, including genes implicated in DNA repair, immune function and immune function.
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways
Lisette Stolk,John R. B. Perry,Daniel I. Chasman,Chunyan He,Massimo Mangino,Patrick Sulem,Maja Barbalić,Linda Broer,Enda M. Byrne,Florian Ernst,Tõnu Esko,Nora Franceschini,Daniel F. Gudbjartsson,Jouke-Jan Hottenga,P. Kraft,Patrick F. McArdle,Eleonora Porcu,So-Youn Shin,Albert V. Smith,S. van Wingerden,Guangju Zhai,Wei V. Zhuang,Eva Albrecht,Behrooz Z. Alizadeh,Thor Aspelund,Stefania Bandinelli,Lovorka Barać Lauc,Jacques S. Beckmann,Mladen Boban,Eric Boerwinkle,Frank J.M. Broekmans,Andrea Burri,Harry Campbell,Stephen J. Chanock,Constance Chen,Marilyn C. Cornelis,Tanguy Corre,Andrea D. Coviello,Pio D'Adamo,Gail Davies,U de Faire,E.J.C. de Geus,Ian J. Deary,George Dedoussis,Panagiotis Deloukas,Shah Ebrahim,G. Eiriksdottir,Valur Emilsson,Johan G. Eriksson,B. C. Fauser,Liana Ferreli,Luigi Ferrucci,Krista Fischer,Aaron R. Folsom,Melissa E. Garcia,Paolo Gasparini,Christian Gieger,Nicole L. Glazer,D. E. Grobbee,Per Hall,T. Haller,Susan E. Hankinson,M. Hass,Caroline Hayward,A. C. Heath,Albert Hofman,Erik Ingelsson,A. C. J. W. Janssens,Andrew D. Johnson,David Karasik,Sharon L.R. Kardia,Jules J. Keyzer,Douglas P. Kiel,Ivana Kolcic,Zoltán Kutalik,Jari Lahti,Sandra Lai,Triin Laisk,Joop S.E. Laven,Debbie A Lawlor,Jianjun Liu,Lorna M. Lopez,Yvonne V. Louwers,Patrik K. E. Magnusson,Mara Marongiu,Nicholas G. Martin,Irena Martinović Klarić,Corrado Masciullo,Barbara McKnight,S. E. Medland,David Melzer,Vincent Mooser,Pau Navarro,Anne B. Newman,Dale R. Nyholt,N. C. Onland-Moret,Aarno Palotie,Guillaume Paré,Alex Parker,N. L. Pedersen,P. H. M. Peeters,Giorgio Pistis,Andrew S. Plump,Ozren Polasek,Victor J M Pop,Bruce M. Psaty,Katri Räikkönen,Emil Rehnberg,Jerome I. Rotter,Igor Rudan,Cinzia Sala,Andres Salumets,Angelo Scuteri,AB Singleton,Jennifer A. Smith,Harold Snieder,Nicole Soranzo,Simon N. Stacey,John M. Starr,Maria G. Stathopoulou,Kathy Stirrups,Ronald P. Stolk,Unnur Styrkarsdottir,Yan V. Sun,Albert Tenesa,Barbara Thorand,Daniela Toniolo,Laufey Tryggvadottir,Kim Tsui,S. Ulivi,R. M. van Dam,Y. T. van der Schouw,C. H. van Gils,P. van Nierop,Jacqueline M. Vink,Peter M. Visscher,Marlies Voorhuis,G. Waeber,Henri Wallaschofski,H. E. Wichmann,Elisabeth Widen,C. J. Wijnands-van Gent,Gonneke Willemsen,James F. Wilson,Bruce H. R. Wolffenbuttel,A. F. Wright,Laura M. Yerges-Armstrong,Tatijana Zemunik,Lina Zgaga,M. C. Zillikens,Marek Zygmunt,T. L. Study,Alice M. Arnold,Dorret I. Boomsma,Julie E. Buring,Laura Crisponi,Ellen W. Demerath,Vilmundur Gudnason,Tamara B. Harris,Frank B. Hu,David J. Hunter,Lenore J. Launer,Andres Metspalu,Grant W. Montgomery,Ben A. Oostra,Paul M. Ridker,Serena Sanna,David Schlessinger,Tim D. Spector,Kari Stefansson,Elizabeth A. Streeten,Unnur Thorsteinsdottir,Manuela Uda,André G. Uitterlinden,C M van Duijn,Henry Völzke,Anna Murray,Joanne M. Murabito,Jenny A. Visser,Kathryn L. Lunetta +179 more
TL;DR: A meta-analysis of genome-wide association studies in 38,968 women of European descent identified 13 loci newly associated with age at natural menopause, and candidate genes located at these newly associated loci include genes implicated in DNA repair and immune function.
Journal ArticleDOI
High-Resolution Phylogenetic Analysis of Southeastern Europe Traces Major Episodes of Paternal Gene Flow Among Slavic Populations
Marijana Peričić,Lovorka Barać Lauc,Irena Martinović Klarić,Siiri Rootsi,Branka Janićijević,Igor Rudan,Rifet Terzić,Ivanka Čolak,Ante Kvesić,Dan Popović,Ana Šijački,Ibrahim Behluli,Dobrivoje Đorđević,Ljudmila Efremovska,Đorđe D. Bajec,Branislav D. Stefanović,Richard Villems,Pavao Rudan +17 more
TL;DR: The extent and nature of southeastern Europe (SEE) paternal genetic contribution to the European genetic landscape were explored based on a high-resolution Y chromosome analysis involving 681 males from seven populations in the region, finding that five major haplogroups comprise more than 70% of SEE total genetic variation.
Journal ArticleDOI
Y chromosomal heritage of Croatian population and its island isolates
Lovorka Barać,Marijana Peričić,Irena Martinović Klarić,Siiri Rootsi,Branka Janićijević,Toomas Kivisild,Jüri Parik,Igor Rudan,Richard Villems,Pavao Rudan +9 more
TL;DR: High frequency of haplogroup I in Croatian populations and the phylogeographic pattern in its background STR diversity over Europe make Adriatic coast one likely source of the recolonization of Europe following the Last Glacial Maximum.