J
Joern Piel
Researcher at ETH Zurich
Publications - 11
Citations - 2007
Joern Piel is an academic researcher from ETH Zurich. The author has contributed to research in topics: Microbiome & Polyketide synthase. The author has an hindex of 8, co-authored 11 publications receiving 1651 citations. Previous affiliations of Joern Piel include University of Bonn.
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Journal ArticleDOI
Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature
Paul G. Arnison,Mervyn J. Bibb,Gabriele Bierbaum,Albert A. Bowers,Tim S. Bugni,Grzegorz Bulaj,Julio A. Camarero,Dominic J. Campopiano,Gregory L. Challis,Jon Clardy,Paul D. Cotter,David J. Craik,Michael J. Dawson,Elke Dittmann,Stefano Donadio,Pieter C. Dorrestein,K. D. Entian,Michael A. Fischbach,John S. Garavelli,Ulf Göransson,Christian W. Gruber,Daniel H. Haft,Thomas Hemscheidt,Christian Hertweck,Colin Hill,Alexander R. Horswill,Marcel Jaspars,Wendy L. Kelly,Judith P. Klinman,Oscar P. Kuipers,A. James Link,Wen Liu,Mohamed A. Marahiel,Douglas A. Mitchell,Gert N. Moll,Bradley S. Moore,Rolf Müller,Satish K. Nair,Ingolf F. Nes,Gillian E. Norris,Baldomero M. Olivera,Hiroyasu Onaka,Mark L. Patchett,Joern Piel,Joern Piel,Martin J. T. Reaney,Sylvie Rebuffat,R. Paul Ross,Hans-Georg Sahl,Eric W. Schmidt,Michael E. Selsted,Konstantin Severinov,Ben Shen,Kaarina Sivonen,Leif Smith,Torsten Stein,Roderich D. Süssmuth,John R. Tagg,Gong-Li Tang,Andrew W. Truman,John C. Vederas,Christopher T. Walsh,Jonathan D. Walton,Silke C. Wenzel,Joanne M. Willey,Wilfred A. van der Donk +65 more
TL;DR: This review presents recommended nomenclature for the biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs), a rapidly growing class of natural products.
Journal ArticleDOI
Complex microbiome underlying secondary and primary metabolism in the tunicate-Prochloron symbiosis
Mohamed S. Donia,W. Florian Fricke,Frédéric Partensky,James E. Cox,Sherif I. Elshahawi,James R. White,Adam M. Phillippy,Michael C. Schatz,Michael C. Schatz,Joern Piel,Margo G. Haygood,Jacques Ravel,Eric W. Schmidt +12 more
TL;DR: In this paper, the authors present metagenomes, chemistry, and microbiomes of four related Lissoclinum patella tunicate samples from a wide geographical range of the tropical Pacific.
Journal ArticleDOI
Oxidative dearomatisation: the key step of sorbicillinoid biosynthesis
Ahmed al Fahad,Amira Abood,Katja M. Fisch,Anna Osipow,Jack R. Davison,Marija Avramovic,Craig P. Butts,Joern Piel,Joern Piel,Thomas J. Simpson,Russell J. Cox,Russell J. Cox +11 more
TL;DR: In this article, an FAD-dependent monooxygenase encoding gene (SorbC) was cloned from Penicillium chrysogenum E01-10/3 and expressed as a soluble protein in Escherichia coli.
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Single-bacterial genomics validates rich and varied specialized metabolism of uncultivated Entotheonella sponge symbionts
Tetsushi Mori,Tetsushi Mori,Jackson K. B. Cahn,Micheal C. Wilson,Roy A. Meoded,Vincent Wiebach,Ana Flavia Canovas Martinez,Eric J. N. Helfrich,Andreas Albersmeier,Daniel Wibberg,Steven M. Dätwyler,Ray Keren,Adi Lavy,Christian Rückert,Micha Ilan,Jörn Kalinowski,Shigeki Matsunaga,Haruko Takeyama,Joern Piel +18 more
TL;DR: In this paper, a single symbiont, the filamentous, multicellular organism "Candidatus Entotheonella factor," produces almost all of these compounds, including misakinolide and theonellamide.
Journal ArticleDOI
A close look at a ketosynthase from a trans-acyltransferase modular polyketide synthase.
Abram Axelrod,Matthew Jenner,Christoph Kohlhaas,Annette Kampa,Neil J. Oldham,Joern Piel,Adrian T. Keatinge-Clay +6 more
TL;DR: The structure of the cysteine-to-serine mutant of the ketosynthase acylated by its natural substrate provides high-resolution details of how a native polyketide intermediate is bound and helps explain the basis of ketoslynthase substrate specificity.