S
Sylvie Rebuffat
Researcher at Centre national de la recherche scientifique
Publications - 158
Citations - 8487
Sylvie Rebuffat is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Peptaibol & Microcin. The author has an hindex of 43, co-authored 151 publications receiving 7068 citations. Previous affiliations of Sylvie Rebuffat include French Institute of Health and Medical Research & University of Marburg.
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Journal ArticleDOI
Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature
Paul G. Arnison,Mervyn J. Bibb,Gabriele Bierbaum,Albert A. Bowers,Tim S. Bugni,Grzegorz Bulaj,Julio A. Camarero,Dominic J. Campopiano,Gregory L. Challis,Jon Clardy,Paul D. Cotter,David J. Craik,Michael J. Dawson,Elke Dittmann,Stefano Donadio,Pieter C. Dorrestein,K. D. Entian,Michael A. Fischbach,John S. Garavelli,Ulf Göransson,Christian W. Gruber,Daniel H. Haft,Thomas Hemscheidt,Christian Hertweck,Colin Hill,Alexander R. Horswill,Marcel Jaspars,Wendy L. Kelly,Judith P. Klinman,Oscar P. Kuipers,A. James Link,Wen Liu,Mohamed A. Marahiel,Douglas A. Mitchell,Gert N. Moll,Bradley S. Moore,Rolf Müller,Satish K. Nair,Ingolf F. Nes,Gillian E. Norris,Baldomero M. Olivera,Hiroyasu Onaka,Mark L. Patchett,Joern Piel,Joern Piel,Martin J. T. Reaney,Sylvie Rebuffat,R. Paul Ross,Hans-Georg Sahl,Eric W. Schmidt,Michael E. Selsted,Konstantin Severinov,Ben Shen,Kaarina Sivonen,Leif Smith,Torsten Stein,Roderich D. Süssmuth,John R. Tagg,Gong-Li Tang,Andrew W. Truman,John C. Vederas,Christopher T. Walsh,Jonathan D. Walton,Silke C. Wenzel,Joanne M. Willey,Wilfred A. van der Donk +65 more
TL;DR: This review presents recommended nomenclature for the biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs), a rapidly growing class of natural products.
Journal ArticleDOI
Microcins, gene-encoded antibacterial peptides from enterobacteria
TL;DR: This review provides an updated overview of microcin structures, antibacterial activities, genetic systems and biosyntheses, as well as of their mechanisms of action.
Journal ArticleDOI
New developments in RiPP discovery, enzymology and engineering
Manuel Montalbán-López,Thomas A Scott,Sangeetha Ramesh,Imran R Rahman,Auke J. van Heel,Jakob H Viel,Vahe Bandarian,Elke Dittmann,Olga Genilloud,Yuki Goto,María José Grande Burgos,Colin Hill,Seokhee Kim,Jesko Koehnke,John A. Latham,A. James Link,Beatriz Martínez,Satish K. Nair,Yvain Nicolet,Sylvie Rebuffat,Hans-Georg Sahl,Dipti Sareen,Eric W. Schmidt,Lutz Schmitt,Konstantin Severinov,Roderich D. Süssmuth,Andrew W. Truman,Huan Wang,Jing-Ke Weng,Gilles P. van Wezel,Qi Zhang,Jin Zhong,Jörn Piel,Douglas A. Mitchell,Oscar P. Kuipers,Wilfred A. van der Donk +35 more
TL;DR: The review discusses the new classes of RiPPs that have been discovered, the advances in the understanding of the installation of both primary and secondary post-translational modifications, and the mechanisms by which the enzymes recognize the leader peptides in their substrates.
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Structural changes of region 1-16 of the Alzheimer disease amyloid beta-peptide upon zinc binding and in vitro aging.
Séverine Zirah,Sergey A. Kozin,Alexey K. Mazur,Alain Blond,Michel Cheminant,Isabelle Ségalas-Milazzo,Pascale Debey,Sylvie Rebuffat +7 more
TL;DR: The solution structure of the Aβ-(1-16)-Zn2+ complex in aqueous solution at pH 6.5 was determined from NMR data and the potentiality of the region 1-16 of Aβ to be used as a therapeutic target was identified.
Journal ArticleDOI
Identification of peptaibols from Trichoderma virens and cloning of a peptaibol synthetase
Aric Wiest,Darlene Grzegorski,Biwen Xu,Christophe Goulard,Sylvie Rebuffat,Daniel J. Ebbole,Bernard Bodo,Charles M. Kenerley +7 more
TL;DR: Preliminary characterization of a 62.8-kb continuous open reading frame encoding a peptaibol synthetase from T. virens shows the predicted protein structure consists of 18 peptide synthetases modules with additional modifying domains at the N- and C-termini.