J
Joseph A.C. Delaney
Researcher at University of Manitoba
Publications - 187
Citations - 6620
Joseph A.C. Delaney is an academic researcher from University of Manitoba. The author has contributed to research in topics: Population & Cohort. The author has an hindex of 36, co-authored 174 publications receiving 5623 citations. Previous affiliations of Joseph A.C. Delaney include Johns Hopkins University & Food and Drug Administration.
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Journal ArticleDOI
Use of gastric acid-suppressive agents and the risk of community-acquired Clostridium difficile-associated disease
TL;DR: The use of acid-suppressive therapy, particularly proton pump inhibitors, is associated with an increased risk of community-acquired C difficile and the unexpected increase in risk with nonsteroidal anti-inflammatory drug use should be investigated further.
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HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.
Daniel I. Swerdlow,David Preiss,Karoline Kuchenbaecker,Michael V. Holmes,Jorgen Engmann,Tina Shah,Reecha Sofat,Stefan Stender,Paul C. D. Johnson,Robert A. Scott,Maarten Leusink,Niek Verweij,Stephen J. Sharp,Yiran Guo,Claudia Giambartolomei,Christina Chung,Anne Peasey,Antoinette Amuzu,KaWah Li,Jutta Palmen,Philip N. Howard,Jackie A. Cooper,Fotios Drenos,Yun Li,Gordon D.O. Lowe,John Gallacher,Marlene C. W. Stewart,Ioanna Tzoulaki,Sarah G. Buxbaum,Daphne L. van der A,Nita G. Forouhi,N. Charlotte Onland-Moret,Yvonne T. van der Schouw,Renate B. Schnabel,Jaroslav A. Hubacek,Ruzena Kubinova,Migle Baceviciene,Abdonas Tamosiunas,Andrzej Pajak,Romanvan Topor-Madry,Urszula Stepaniak,Sofia Malyutina,Damiano Baldassarre,Bengt Sennblad,Elena Tremoli,Ulf de Faire,Fabrizio Veglia,Ian Ford,J. Wouter Jukema,Rudi G. J. Westendorp,Gert J. de Borst,Pim A. de Jong,Ale Algra,Wilko Spiering,Anke H. Maitland-van der Zee,Olaf H. Klungel,Anthonius de Boer,Pieter A. Doevendans,Charles B. Eaton,Jennifer G. Robinson,David Duggan,John Kjekshus,John R. Downs,Antonio M. Gotto,Anthony C Keech,Roberto Marchioli,Gianni Tognoni,Peter S. Sever,Neil R Poulter,David D. Waters,Terje R. Pedersen,Pierre Amarenco,Haruo Nakamura,John J.V. McMurray,James Lewsey,Daniel I. Chasman,Paul M. Ridker,Aldo P. Maggioni,Luigi Tavazzi,Kausik K. Ray,Sreenivasa Rao Kondapally Seshasai,JoAnn E. Manson,Jackie F. Price,Peter H. Whincup,Richard W Morris,Debbie A Lawlor,George Davey Smith,Yoav Ben-Shlomo,Pamela J. Schreiner,Myriam Fornage,David S. Siscovick,Mary Cushman,Meena Kumari,Nicholas J. Wareham,W M Monique Verschuren,Susan Redline,Sanjay R. Patel,John C. Whittaker,Anders Hamsten,Joseph A.C. Delaney,Caroline Dale,Tom R. Gaunt,Andrew Wong,Diana Kuh,Rebecca Hardy,Sekar Kathiresan,Berta Almoguera Castillo,Pim van der Harst,Eric J. Brunner,Anne Tybjærg-Hansen,Michael Marmot,Ronald M. Krauss,Michael Y. Tsai,Josef Coresh,Ron C. Hoogeveen,Bruce M. Psaty,Leslie A. Lange,Hakon Hakonarson,Frank Dudbridge,Steve E. Humphries,Philippa J. Talmud,Mika Kivimäki,Nicholas J. Timpson,Claudia Langenberg,Folkert W. Asselbergs,Mikhail Voevoda,Martin Bobak,Hynek Pikhart,James G. Wilson,Alexander P. Reiner,Brendan J. Keating,Aroon D. Hingorani,Naveed Sattar +132 more
TL;DR: The increased risk of type 2 diabetes noted with statins is at least partially explained by HMGCR inhibition.
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Preclinical atherosclerosis due to HIV infection: carotid intima-medial thickness measurements from the FRAM study.
Carl Grunfeld,Joseph A.C. Delaney,Christine Wanke,Judith S. Currier,Rebecca Scherzer,Mary L. Biggs,Phyllis C. Tien,Michael G. Shlipak,Stephen Sidney,Joseph F. Polak,Daniel H. O'Leary,Peter Bacchetti,Richard A. Kronmal +12 more
TL;DR: The stronger association of HIV infection with IMT in the internal/bulb region compared with the common carotid may explain previous discrepancies in the literature and was similar to that of traditional CVD risk factors, such as smoking.
Journal ArticleDOI
Comparison of coronary artery calcium presence, carotid plaque presence, and carotid intima-media thickness for cardiovascular disease prediction in the Multi-Ethnic Study of Atherosclerosis.
Adam D. Gepner,Rebekah Young,Joseph A.C. Delaney,Matthew C. Tattersall,Michael J. Blaha,Wendy S. Post,Rebecca F. Gottesman,Richard A. Kronmal,Matthew J. Budoff,Gregory L. Burke,Aaron R. Folsom,Kiang Liu,Joel D. Kaufman,James H. Stein +13 more
TL;DR: In adults without CVD, CAC presence improves prediction of CVD and CHD more than carotid plaque presence or high IMT orCarotid ultrasound parameters performed similarly for stroke/transient ischemic attack event prediction.
Journal ArticleDOI
Drug–drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding
TL;DR: Drug combinations involving antiplatelets and anticoagulants are associated with a high risk of gastrointestinal bleeding beyond that associated with each drug used alone, and Physicians should be aware of these risks to better assess their patients' therapeutic risk–benefit profiles.