K
Kannanganattu V. Prasanth
Researcher at University of Illinois at Urbana–Champaign
Publications - 88
Citations - 9579
Kannanganattu V. Prasanth is an academic researcher from University of Illinois at Urbana–Champaign. The author has contributed to research in topics: RNA & Chromatin. The author has an hindex of 38, co-authored 80 publications receiving 8291 citations. Previous affiliations of Kannanganattu V. Prasanth include Cold Spring Harbor Laboratory & Banaras Hindu University.
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Journal ArticleDOI
The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation.
Vidisha Tripathi,Jonathan D. Ellis,Zhen Shen,David Y. Song,Qun Pan,Andrew T. Watt,Susan M. Freier,C. Frank Bennett,Alok Sharma,Paula A. Bubulya,Benjamin J. Blencowe,Supriya G. Prasanth,Kannanganattu V. Prasanth +12 more
TL;DR: Evidence is provided for a role for the long nuclear-retained regulatory RNA, MALAT1 in AS regulation and for the role for an nrRNA in the regulation of gene expression, which suggests that MALat1 regulates AS by modulating the levels of active SR proteins.
Journal ArticleDOI
Regulating Gene Expression through RNA Nuclear Retention
Kannanganattu V. Prasanth,Supriya G. Prasanth,Zhenyu Xuan,Stephen Hearn,Susan M. Freier,C. Frank Bennett,Michael Q. Zhang,David L. Spector +7 more
TL;DR: A role of the cell nucleus in harboring RNA molecules that are not immediately needed to produce proteins but whose cytoplasmic presence is rapidly required upon physiologic stress is revealed.
Journal ArticleDOI
From silencing to gene expression: real-time analysis in single cells.
Susan M. Janicki,Toshiro Tsukamoto,Simone E Salghetti,William P. Tansey,Ravi Sachidanandam,Kannanganattu V. Prasanth,Thomas Ried,Yaron Shav-Tal,Edouard Bertrand,Robert H. Singer,David L. Spector +10 more
TL;DR: An inducible system to visualize gene expression at the levels of DNA, RNA and protein in living cells is developed, able to correlate changes in chromatin structure with the progression of transcriptional activation allowing for a real-time integrative view of gene expression.
Journal ArticleDOI
Long noncoding RNA MALAT1 controls cell cycle progression by regulating the expression of oncogenic transcription factor B-MYB.
Vidisha Tripathi,Zhen Shen,Arindam Chakraborty,Sumanprava Giri,Susan M. Freier,Xiaolin Wu,Yongqing Zhang,Myriam Gorospe,Supriya G. Prasanth,Ashish Lal,Kannanganattu V. Prasanth +10 more
TL;DR: It is demonstrated that MALAT1 levels are regulated during normal cell cycle progression, and mechanistic insights on the role of MALat1 in regulating cellular proliferation are provided.
Journal ArticleDOI
A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression.
Delphine Bernard,Kannanganattu V. Prasanth,Kannanganattu V. Prasanth,Vidisha Tripathi,Sabrina Colasse,Tetsuya Nakamura,Zhenyu Xuan,Michael Q. Zhang,Frédéric Sedel,Laurent Jourdren,Fanny Coulpier,Antoine Triller,David L. Spector,Alain Bessis +13 more
TL;DR: DNA microarray analysis in Malat1‐depleted neuroblastoma cells indicates that Malat 1 controls the expression of genes involved not only in nuclear processes, but also in synapse function, suggesting that Mal at1 regulates synapse formation by modulating the expressionof genes involved in synapses formation and/or maintenance.