Ling Lu

TL;DR: Vitamin D deficiency is common in the middle-aged and elderly Chinese population, and a low 25(OH)D level is significantly associated with an increased risk of having metabolic syndrome and insulin resistance.

TL;DR: A meta-analysis of associations between BMI and ∼2.5 million genotyped or imputed single nucleotide polymorphisms among 86 757 individuals of Asian ancestry, followed by in silico and de novo replication among 7488-47 352 additional Asian-ancestry individuals finds the association of BMI with rs2237892, rs671 and rs12229654 was significantly stronger among men than among women.

TL;DR: Two novel type 2 diabetes loci are identified, including G-protein–coupled receptor kinase 5 (GRK5) and RASGRP1, of which the association signal at GRK5 seems to be specific to East Asians, which may shed light on the ethnic differences in T2D susceptibility.

TL;DR: A meta-analysis of GWASs of blood pressure and hypertension in 11 816 subjects followed by replication studies including 69 146 additional individuals identified genome-wide significant associations with blood pressure, which included variants at three new loci and a newly discovered variant near SLC4A7.

TL;DR: Depressive symptoms are not associated with 25(OH)D concentrations in middle-aged and elderly Chinese, and the association was substantially attenuated after controlling for various confounding factors, and disappeared after including geographic location in the model.