Yong Gao

TL;DR: To identify genetic susceptibility loci for hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) in the Chinese population, a genome-wide association study in 2,514 chronic HBV carriers followed by a 2-stage validation among 6 independent populations of chronicHBV carriers showed that HCC risk was significantly associated with two independent loci.

TL;DR: A meta-analysis of associations between BMI and ∼2.5 million genotyped or imputed single nucleotide polymorphisms among 86 757 individuals of Asian ancestry, followed by in silico and de novo replication among 7488-47 352 additional Asian-ancestry individuals finds the association of BMI with rs2237892, rs671 and rs12229654 was significantly stronger among men than among women.

TL;DR: An inverse association of serum osteocalcin levels with MetS is identified, independent from the well-known MetS risk factors, which may represent a further mechanism for the elevated cardiovascular disease or type 2 diabetes mellitus risk in a Chinese male population.

TL;DR: The present meta-analysis provides support for the hypothesis that aspirin use is inversely related to PCa incidence and PCa-specific mortality.

TL;DR: Results suggest that AMPK activation with clinically approved agents, such as metformin, may facilitate bacterial eradication in sepsis and other inflammatory conditions associated with inhibition of neutrophil activation and chemotaxis.