Naoyuki Takashima

TL;DR: The existence of higher stroke rates and lower CHD rates in Asian countries than in Western countries and the respective risk factors for this are discussed on the basis of extensive reviews of cohort studies and whether these risk factors differ from those of Western countries are discussed.

TL;DR: A meta-analysis of associations between BMI and ∼2.5 million genotyped or imputed single nucleotide polymorphisms among 86 757 individuals of Asian ancestry, followed by in silico and de novo replication among 7488-47 352 additional Asian-ancestry individuals finds the association of BMI with rs2237892, rs671 and rs12229654 was significantly stronger among men than among women.

TL;DR: A large-scale genome-wide association study of 168,228 individuals of Japanese ancestry with genotype imputation with genotypes imputation detected eight new susceptibility loci and Japanese-specific rare variants contributing to disease severity and increased cardiovascular mortality, and a trans-ancestry meta-analysis found 35 additional new loci.

TL;DR: It is demonstrated that increased baPWV is an independent predictor of all-cause mortality in the Japanese population.

TL;DR: Serum RBP4 levels did not correlate with the fasting blood glucose level, waist-to-hip ratio, body-mass index (BMI), systolic blood pressure, or fasting insulin level, and it seems unlikely thatRBP4 will be useful for assessing the risk of type 2 diabetes in Japanese people.