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Mercedes Villena
Researcher at Higher University of San Andrés
Publications - 59
Citations - 4652
Mercedes Villena is an academic researcher from Higher University of San Andrés. The author has contributed to research in topics: Population & Effects of high altitude on humans. The author has an hindex of 23, co-authored 58 publications receiving 3981 citations. Previous affiliations of Mercedes Villena include International Business Broker's Association.
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Journal ArticleDOI
Ancient human genomes suggest three ancestral populations for present-day Europeans
Iosif Lazaridis,Iosif Lazaridis,Nick Patterson,Alissa Mittnik,Gabriel Renaud,Swapan Mallick,Swapan Mallick,Karola Kirsanow,Peter H. Sudmant,Joshua G. Schraiber,Joshua G. Schraiber,Sergi Castellano,Mark Lipson,Bonnie Berger,Bonnie Berger,Christos Economou,Ruth Bollongino,Qiaomei Fu,Kirsten I. Bos,Susanne Nordenfelt,Susanne Nordenfelt,Heng Li,Heng Li,Cesare de Filippo,Kay Prüfer,Susanna Sawyer,Cosimo Posth,Wolfgang Haak,Fredrik Hallgren,Elin Fornander,Nadin Rohland,Nadin Rohland,Dominique Delsate,Michael Francken,Jean-Michel Guinet,Joachim Wahl,George Ayodo,Hamza A. Babiker,Hamza A. Babiker,Graciela Bailliet,Elena Balanovska,Oleg Balanovsky,Ramiro Barrantes,Gabriel Bedoya,Haim Ben-Ami,Judit Bene,Fouad Berrada,Claudio M. Bravi,Francesca Brisighelli,George B.J. Busby,Francesco Calì,Mikhail Churnosov,David E. C. Cole,Daniel Corach,Larissa Damba,George van Driem,Stanislav Dryomov,Jean-Michel Dugoujon,Sardana A. Fedorova,Irene Gallego Romero,Marina Gubina,Michael F. Hammer,Brenna M. Henn,Tor Hervig,Ugur Hodoglugil,Aashish R. Jha,Sena Karachanak-Yankova,Rita Khusainova,Elza Khusnutdinova,Rick A. Kittles,Toomas Kivisild,William Klitz,Vaidutis Kučinskas,Alena Kushniarevich,Leila Laredj,Sergey Litvinov,Theologos Loukidis,Theologos Loukidis,Robert W. Mahley,Béla Melegh,Ene Metspalu,Julio Molina,Joanna L. Mountain,Klemetti Näkkäläjärvi,Desislava Nesheva,Thomas B. Nyambo,Ludmila P. Osipova,Jüri Parik,Fedor Platonov,Olga L. Posukh,Valentino Romano,Francisco Rothhammer,Francisco Rothhammer,Igor Rudan,Ruslan Ruizbakiev,Hovhannes Sahakyan,Hovhannes Sahakyan,Antti Sajantila,Antonio Salas,Elena B. Starikovskaya,Ayele Tarekegn,Draga Toncheva,Shahlo Turdikulova,Ingrida Uktveryte,Olga Utevska,René Vasquez,Mercedes Villena,Mikhail Voevoda,Cheryl A. Winkler,Levon Yepiskoposyan,Pierre Zalloua,Pierre Zalloua,Tatijana Zemunik,Alan Cooper,Cristian Capelli,Mark G. Thomas,Andres Ruiz-Linares,Sarah A. Tishkoff,Lalji Singh,Kumarasamy Thangaraj,Richard Villems,Richard Villems,Richard Villems,David Comas,Rem I. Sukernik,Mait Metspalu,Matthias Meyer,Evan E. Eichler,Joachim Burger,Montgomery Slatkin,Svante Pääbo,Janet Kelso,David Reich,David Reich,David Reich,Johannes Krause,Johannes Krause +136 more
TL;DR: It is shown that most present-day Europeans derive from at least three highly differentiated populations: west European hunter-gatherers, who contributed ancestry to all Europeans but not to Near Easterners; ancient north Eurasians related to Upper Palaeolithic Siberians; and early European farmers, who were mainly of Near Eastern origin but also harboured west Europeanhunter-gatherer related ancestry.
Journal ArticleDOI
Reconstructing Native American population history
David Reich,David Reich,Nick Patterson,Desmond Campbell,Desmond Campbell,Arti Tandon,Arti Tandon,Stéphane Mazières,Stéphane Mazières,Nicolas Ray,María Victoria Parra,María Victoria Parra,Winston Rojas,Winston Rojas,Constanza Duque,Constanza Duque,Natalia Mesa,Natalia Mesa,Luis F. García,Omar Triana,Silvia Blair,Amanda Maestre,Juan Carlos Dib,Claudio M. Bravi,Claudio M. Bravi,Graciela Bailliet,Daniel Corach,Tábita Hünemeier,Tábita Hünemeier,Maria Cátira Bortolini,Francisco M. Salzano,Maria Luiza Petzl-Erler,Victor Acuña-Alonzo,Carlos A. Aguilar-Salinas,Samuel Canizales-Quinteros,Teresa Tusié-Luna,Laura Riba,Maricela Rodríguez-Cruz,Mardia López-Alarcón,Ramón Mauricio Coral-Vázquez,Thelma Canto-Cetina,Irma Silva-Zolezzi,Juan Carlos Fernández-López,Alejandra V. Contreras,Gerardo Jimenez-Sanchez,María José Gómez-Vázquez,Julio Molina,Angel Carracedo,Antonio Salas,Carla Gallo,Giovanni Poletti,David B. Witonsky,Gorka Alkorta-Aranburu,Rem I. Sukernik,Ludmila P. Osipova,Sardana A. Fedorova,René Vasquez,Mercedes Villena,Claudia Moreau,Ramiro Barrantes,David L. Pauls,Laurent Excoffier,Laurent Excoffier,Gabriel Bedoya,Francisco Rothhammer,Jean-Michel Dugoujon,Georges Larrouy,William Klitz,Damian Labuda,Judith R. Kidd,Kenneth K. Kidd,Anna Di Rienzo,Nelson B. Freimer,Alkes L. Price,Alkes L. Price,Andres Ruiz-Linares +75 more
TL;DR: It is shown that the initial peopling followed a southward expansion facilitated by the coast, with sequential population splits and little gene flow after divergence, especially in South America.
Ancient human genomes suggest three ancestral populations for present-day Europeans
Iosif Lazaridis,Iosif Lazaridis,Nick Patterson,Alissa Mittnik,Gabriel Renaud,Swapan Mallick,Swapan Mallick,Karola Kirsanow,Peter H. Sudmant,Joshua G. Schraiber,Joshua G. Schraiber,Sergi Castellano,Mark Lipson,Bonnie Berger,Bonnie Berger,Christos Economou,Ruth Bollongino,Qiaomei Fu,Kirsten I. Bos,Susanne Nordenfelt,Susanne Nordenfelt,Heng Li,Heng Li,Cesare de Filippo,Kay Prüfer,Susanna Sawyer,Cosimo Posth,Wolfgang Haak,Fredrik Hallgren,Elin Fornander,Nadin Rohland,Nadin Rohland,Dominique Delsate,Michael Francken,Jean-Michel Guinet,Joachim Wahl,George Ayodo,Hamza A. Babiker,Hamza A. Babiker,Graciela Bailliet,Elena Balanovska,Oleg Balanovsky,Ramiro Barrantes,Gabriel Bedoya,Haim Ben-Ami,Judit Bene,Fouad Berrada,Claudio M. Bravi,Francesca Brisighelli,George B.J. Busby,Francesco Calì,Mikhail Churnosov,David E. C. Cole,Daniel Corach,Larissa Damba,George van Driem,Stanislav Dryomov,Jean-Michel Dugoujon,Sardana A. Fedorova,Irene Gallego Romero,Marina Gubina,Michael F. Hammer,Brenna M. Henn,Tor Hervig,Ugur Hodoglugil,Aashish R. Jha,Sena Karachanak-Yankova,Rita Khusainova,Elza Khusnutdinova,Rick A. Kittles,Toomas Kivisild,William Klitz,Vaidutis Kučinskas,Alena Kushniarevich,Leila Laredj,Sergey Litvinov,Theologos Loukidis,Theologos Loukidis,Robert W. Mahley,Béla Melegh,Ene Metspalu,Julio Molina,Joanna L. Mountain,Klemetti Näkkäläjärvi,Desislava Nesheva,Thomas B. Nyambo,Ludmila P. Osipova,Jüri Parik,Fedor Platonov,Olga L. Posukh,Valentino Romano,Francisco Rothhammer,Francisco Rothhammer,Igor Rudan,Ruslan Ruizbakiev,Hovhannes Sahakyan,Hovhannes Sahakyan,Antti Sajantila,Antonio Salas,Elena B. Starikovskaya,Ayele Tarekegn,Draga Toncheva,Shahlo Turdikulova,Ingrida Uktveryte,Olga Utevska,René Vasquez,Mercedes Villena,Mikhail Voevoda,Cheryl A. Winkler,Levon Yepiskoposyan,Pierre Zalloua,Pierre Zalloua,Tatijana Zemunik,Alan Cooper,Cristian Capelli,Mark G. Thomas,Andres Ruiz-Linares,Sarah A. Tishkoff,Lalji Singh,Kumarasamy Thangaraj,Richard Villems,Richard Villems,Richard Villems,David Comas,Rem I. Sukernik,Mait Metspalu,Matthias Meyer,Evan E. Eichler,Joachim Burger,Montgomery Slatkin,Svante Pääbo,Janet Kelso,David Reich,David Reich,David Reich,Johannes Krause,Johannes Krause +136 more
TL;DR: The authors showed that most present-day Europeans derive from at least three highly differentiated populations: west European hunter-gatherers, ancient north Eurasians related to Upper Palaeolithic Siberians, who contributed to both Europeans and Near Easterners; and early European farmers, who were mainly of Near Eastern origin but also harboured west European hunters-gatherer related ancestry.
Journal ArticleDOI
Hemoglobin concentration of high-altitude tibetans and bolivian aymara
Cynthia M. Beall,Gary M. Brittenham,Kingman P. Strohl,John Blangero,Sarah Williams-Blangero,Melvyn C. Goldstein,Michael J. Decker,Enrique Vargas,Mercedes Villena,Rudy Soria,Ana Maria Alarcon,Cristina Gonzales +11 more
TL;DR: The present study tested the null hypothesis of no difference in mean hemoglobin concentration of Tibetan and Aymara native residents at 3,800-4,065 meters by using healthy samples that were screened for iron deficiency, abnormal hemoglobins, and thalassemias, recruited and assessed using the same techniques.
Journal ArticleDOI
Pulmonary and Systemic Vascular Dysfunction in Young Offspring of Mothers With Preeclampsia
Pierre-Yves Jayet,Stefano F. Rimoldi,Thomas Stuber,Carlos Salinas Salmòn,Damian Hutter,Emrush Rexhaj,Sébastien Thalmann,Marcos Schwab,Pierre Turini,Céline Sartori-Cucchia,Pascal Nicod,Mercedes Villena,Yves Allemann,Urs Scherrer,Claudio Sartori +14 more
TL;DR: Preeclampsia leaves a persistent defect in the systemic and the pulmonary circulation of the offspring that predisposes to exaggerated hypoxic pulmonary hypertension already during childhood and may contribute to premature cardiovascular disease in the systems circulation later in life.