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Michael A. Matthay

Researcher at University of California, San Francisco

Publications -  1063
Citations -  110857

Michael A. Matthay is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Lung injury & Lung. The author has an hindex of 151, co-authored 998 publications receiving 98687 citations. Previous affiliations of Michael A. Matthay include University of California & Cardiovascular Institute of the South.

Papers
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Mesenchymal stem cells and acute lung injury.

TL;DR: Basic properties of MSCs, their use in preclinical models of lung injury and ARDS, and potential therapeutic mechanisms are reviewed.
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Bench to bedside: targeting coagulation and fibrinolysis in acute lung injury.

TL;DR: Therapies targeted at both activation of coagulations through the extrinsic coagulation cascade and modulation of coAGulation through the protein C system have the potential to favorably impact clinical ALI/acute respiratory distress syndrome.
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Comparison of transesophageal echocardiographic and scintigraphic estimates of left ventricular end-diastolic volume index and ejection fraction in patients following coronary artery bypass grafting

TL;DR: The authors conclude that immediately following CABG, a single cross-sectional TEE image provides a reasonable estimate of EF but not LVEDVI, a commonly used monitor of left ventricular function and filling during cardiac surgery.
Journal Article

Anti-IL-8 autoantibodies in alveolar fluid from patients with the adult respiratory distress syndrome.

TL;DR: It is reported that a major portion of IL-8 in bronchoalveolar fluids from patients with ARDS is associated with anti-IL-8 autoantibody (anti-IL -8:IL- 8 complexes), and the results suggest that anti-il-8Autoantibodies may regulate IL- 8 activity.
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Clinical review: Early treatment of acute lung injury - paradigm shift toward prevention and treatment prior to respiratory failure

TL;DR: Current strategies that target prevention of ALI and some of the most promising pharmacologic agents for early treatment ofALI prior to the onset of respiratory failure that requires mechanical ventilation are discussed.