M
Michael A. Matthay
Researcher at University of California, San Francisco
Publications - 1063
Citations - 110857
Michael A. Matthay is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Lung injury & Lung. The author has an hindex of 151, co-authored 998 publications receiving 98687 citations. Previous affiliations of Michael A. Matthay include University of California & Cardiovascular Institute of the South.
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Journal ArticleDOI
The severity of shock is associated with impaired rates of net alveolar fluid clearance in clinical acute lung injury.
TL;DR: It is suggested that vasopressor use may be a marker of alveolar-capillary barrier permeability in ALI and provide justification for new therapies that enhanceAlveolar epithelial and endothelial barrier integrity in ALi, particularly in patients with shock.
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Diabetes mellitus: a negative predictor for the development of acute respiratory distress syndrome from septic shock.
TL;DR: The first prospective study that identifies a clinical disorder associated with a decreased incidence of acute respiratory distress syndrome (ARDS)— diabetes mellitus and the mechanisms of protection against ARDS in diabetic patients are identified.
Journal ArticleDOI
Hemodynamic Management in the Adult Respiratory Distress Syndrome
TL;DR: In this article, the guiding principles of cardiovascular management of patients with acute respiratory failure (ARDS) should be to maintain adequate cardiac output and tissue oxygenation without worsening the degree of pulmonary edema.
Journal ArticleDOI
The ABO histo-blood group, endothelial activation, and acute respiratory distress syndrome risk in critical illness
John P. Reilly,Nuala J. Meyer,Michael G.S. Shashaty,Brian J. Anderson,Caroline A. G. Ittner,Thomas G. Dunn,Brian Lim,Caitlin M. Forker,Michael Bonk,Ethan D. Kotloff,Rui Feng,Edward Cantu,Nilam S. Mangalmurti,Carolyn S. Calfee,Michael A. Matthay,Carmen Mikacenic,Keith R. Walley,James A. Russell,David C. Christiani,Mark M. Wurfel,Paul N. Lanken,Muredach P. Reilly,Jason D. Christie +22 more
TL;DR: A replicable association between ABO blood type A1 and risk of ARDS among the critically ill possibly mediated through microvascular dysfunction and coagulation is identified.